LSD1 ablation stimulates anti-tumor immunity and enables checkpoint blockade

Histone Variant H2A.Z Defines Cell Identity in Vascular Smooth Muscle Cells as Revealed by Single-Cell Transcriptomics

Joint profiling of chromatin accessibility and gene expression in thousands of single cells

PTEN interacts with the transcription machinery on chromatin and regulates RNA polymerase II-mediated transcription.[RNA-seq and ChIP-seq]

TNF promotes SREBP activity to regulate macrophage polarization and tissue repair

MAFG-driven astrocytes promote CNS inflammation

WDR5 is a conserved regulator of protein synthesis gene expression

RNA-seq and ChIP-seq studies identify multiple pathways relevant for T cell-mediated tumor immunity regulated by SOX4.

An Integrated Epigenomic and Transcriptomic Map of Mouse and Human ab T Cell Development

Disruption of developmental enhancer and PRC2 function by K27M in childhood glioma

Epigenetic Silencing by SETDB1 Suppresses Tumor-cell Intrinsic Immunogenicity

Simple oligonucleotide-based multiplexing of single-cell chromatin accessibility

Retinoic Acid Signaling Drives Differentiation towards Enterocytes in Colorectal Cancer

A primed immune transcriptional program is activated in oligodendroglia in multiple sclerosis

Integration of M. tuberculosis phenotype with single cell RNA-seq to interrogate host macrophage heterogeneity in vivo.

Nucleotide depletion promotes cell fate transitions by inducing DNA replication stress

Elucidation of differential TF binding and epigenome in response to MYCi975.

Transcriptional programs dictating Schwann cell transformation in MPNST

PRMT5 Promotes Progression of Chronic Lymphocytic Leukemia

Mutant-SETBP1 activates transcription of Myc programs to accelerate CSF3R-driven myeloproliferative neoplasms