The chromatin accessibility landscape of T-Cell Acute Lymphoblastic Leukemia

ETV2/ER71 regulates hematovascular lineage generation and vascularization through an H3K9 demethylase, KDM4A

Regulation of sarcomere formation and function in the healthy heart requires a titin intronic enhancer.

Human cytomegalovirus infection coopts chromatin organization to modulate TEAD1 transcription factor activity

A lineage-specific nascent RNA assay unveils principles of gene regulation in tissue biology.

DNA hypomethylation promotes UHRF1- and SUV39H1/H2-dependent crosstalk between H3K18ub and H3K9me3 to reinforce heterochromatin states

DNA hypomethylation promotes UHRF1- and SUV39H1/H2-dependent crosstalk between H3K18ub and H3K9me3 to reinforce heterochromatin states

Viral oncogene manipulates YY1 to alter host 3D genome organization and promote B cell proliferation

DNA hypomethylation promotes UHRF1- and SUV39H1/H2-dependent crosstalk between H3K18ub and H3K9me3 to reinforce heterochromatin states [ChIP-Seq]

Origin of extra-embryonic mesenchyme points to evolutionary novelty in primate early development [ChIP-seq]

Structure-guided development of high-performance antibodies targeting site-specific post-translational modifications

Osmotic disruption of chromatin induces Topoisomerase 2 activity at sites of transcriptional stress [Mnase-Seq]

Stress response factor ATF4 drives liver fibrosis by governing a stress-independent enhancer program to activate hepatic stellate cells

Paired CRISPR screens to map gene regulation in cis and trans

ALKBH1-mediated DNA N6-methyladenine Modification Regulates H3K9me3-dependent Heterochromatin in Neural Tube Development [Cut & Tag]

Mechanosensing regulates plasmacytoid DCs activation in the skin through NRF2 activation

ASCL1 phospho-regulation during lineage restrictions of embryonic stem cells (ATAC-Seq)

Protein kinase N1 mediates phosphorylation of H3.3 serine 31 for rapid gene activation (ATAC-Seq I)

Protein kinase N1 mediates phosphorylation of H3.3 serine 31 for rapid gene activation (ATAC-Seq II)

NK cell cytotoxicity shapes the clonal evolution of B cell leukemia [ATAC-seq]