Single cell transcriptomic analysis (10x Genomics) of mouse colon LP CD4+ Tcells cells isolated from mouse under different infection conditions

Aire regulates chromatin looping by evicting CTCF from domain boundaries and favoring accumulation of cohesin on super-enhancers [ChIP-seq]

FoxP3 associates with enhancer-promoter loops to regulate Treg-specific gene expression [ATAC-seq]

FoxP3 associates with enhancer-promoter loops to regulate Treg-specific gene expression

Thymic epithelial cells co-opt lineage-defining transcription factors to eliminate autoreactive T cells

Single-cell epigenomics and high-density genetic variation resolve the architecture of the Treg regulatory network [scATAC-seq]

Mutations from IPEX patients elicit a range of phenotypes in mice [scATAC-Seq]

Mutations from IPEX patients elicit a range of phenotypes in mice

Homeostatic, repertoire and transcriptional relationships between colon T regulatory cell subsets