IFN-γ activates an immune-like regulatory network in the cardiac vascular endothelium

Cell cycle states of pluripotent cells dictate lineage decisions

Oncogenic lncRNAs alter epigenetic memory at a fragile chromosomal site in human cancer cells

CRISPR screens identify gene targets at breast cancer risk loci

Histone deacetylase 1 maintains lineage integrity through histone acetylome refinement during early embryogenesis

LNCaP prostate cancer cells

Dynamic enhancer landscapes in human craniofacial development

Role of nuclear p38 in the transcriptional response to oxidative stress in Drosophila

Enhancer engagement sustains oncogenic transformation and progression of B-cell precursor acute lymphoblastic leukemia

O-GlcNAcylation controls pro-fibrotic transcriptional regulatory signaling in hepatic stellate cells

A cell type-aware framework for nominating non-coding variants in Mendelian regulatory disorders

Single Cell Sequencing Reveals Early PGC-like Intermediates During Mouse Primed to Naïve Transition

Dor regulates alpha-KG metabolic pathways in mature oligodendrocytes to enhance myelination and reverse age-related remyelination decline

Regulatory Enhancer Profiling of Mesenchymal-type Gastric Cancer Reveals Subtype-Specific Epigenomic Landscapes and Targetable Vulnerabilities

Dependency of NELF-E-SLUG-KAT2B epigenetic axis in breast cancer carcinogenesis

Transcriptional repression by a secondary DNA binding surface of DNA topoisomerase I safeguards against hypertranscription

MYOCD is required for cardiomyocytes induction from human urine cells and fibroblasts through remodeling chromatin

Human Somitoids Generated by Reprogramming Pax8+ Urine Cells

Self-Renewing Presomitic Mesoderm Progenitor Lines Reprogrammed from human urine cells

Dissecting genetic components associated with eye disease using integrative genomic analysis