Activating mutations remodeled the chromatin accessibility landscape to drive distinct regulatory networks in KMT2A-rearranged acute leukemia

Deletion of a state-specific PD-1 enhancer modulates exhausted T cell fate and function [ATAC-seq]

Deletion of a state-specific PD-1 enhancer modulates exhausted T cell fate and function

Transcriptomic and epigenomic profiling of Tet TKO neural stem cells to study NSC specification and multipotency

CUT&Tag, ATAC-seq, bulk RNA-seq and single-nucleus RNA-seq analysis of histone variant H2BE in cortical neurons

EYA1/SIX1/HOXA9 form a trimeric complex that sustains acute myeloid leukaemia

A gene regulatory network of the endothelial-to-hematopoietic transition [ATAC-seq]

Reorganization of H3K9me heterochromatin leads the neuronal impairment via the cascading destruction of KDM3B-centered epigenomic network

ILC2 development requires GATA3-related super-enhancers after lineage commitment

scChIC-seq reveals focusing of global chromatin domains during differentiation

The E3 Ubiquitin Ligase Nedd4L Acts as a Checkpoint Against Activation in Quiescent Muscle Stem Cells

Nucleotide depletion promotes cell fate transitions by inducing DNA replication stress

EHF is an essential regulator of mammary alveolar lineage differentiation and putative suppressor of breast tumorigenesis

Position-dependent function of human sequence-specific transcription factors

Physical and functional interaction among Irf8 enhancers during dendritic cell differentiation

Epigenetic evolution of the Ly49 gene family

EVOLUTIONARY CO-OPTION OF AN ANCESTRAL CLOACAL REGULATORY LANDSCAPE WITH THE EMERGENCE OF DIGITS AND GENITALS

Condensate-promoting ENL mutation induces tumorigenesis via chromatin remodeling

Functionally distinct subset of monocytes in mouse and human blood [ATAC-Seq]

Functionally distinct subset of monocytes in mouse and human blood