Extensive folding variability between homologous chromosomes in mammalian cells [ChIP-Seq]

Extensive folding variability between homologous chromosomes in mammalian cells

Histone H3.3 ensures cell proliferation and genomic stability during myeloid cell development [CUT&RUN]

The ChAHP chromatin remodelling complex regulates a network of neurodevelopmental disorder risk genes to scale the production of neocortical layers (cut&run-seq)

Interaction of methyl-CpG-binding protein 2 (MeCP2) with distinct enhancers in the mouse cortex.

Acetyl-CoA production by Mediator-bound 2-ketoacid dehydrogenases boosts de novo histone acetylation and is regulated by nitric oxide [Med1_Chipseq]

Inflammation switches the chemoattractant requirements for naïve lymphocyte entry into lymph nodes

Mutant IDH impairs chromatin binding by PDGFB to promote chromosome instability [scATAC-Seq]

Decoding Aging in the Heart via Single Cell Dual Omics of Non-Cardiomyocytes

H3.3K122A results in a neomorphic phenotype in mouse embryonic stem cells (CUT&RUN)

Nuclear Factor NFAT5 Governs Cellular Plasticity-Induced KRAS-Targeted Therapy Resistance in Pancreatic Cancer

The H3K9me3 heterochromatin integrity and function are sustained by H3K9me3 methyltransferases-HP1 dependencies [ATAC-Seq]

ATAC-seq of V-SVZ derived aNS cells

EZH2 deletion does not impact acinar cell regeneration but restricts progression to pancreatic cancer in mice [ChIP-seq]

EZH2 deletion does not impact acinar cell regeneration but restricts progression to pancreatic cancer in mice

Renin Regulatory Pathway Inhibition Epigenetically Silences *Ren1* (ChIP-Seq)

Multimodal Hox5 activity generates motor neuron diversity [ChIP-seq]

Antagonism between H3K27me3 and genome-lamina association drives atypical spatial genome organization in the totipotent embryo [scDam&T-seq]

Transcription factor Ikzf1 associates with Foxp3 to repress gene expression in Treg cells and limit autoimmunity and anti-tumor immunity

Transcription factor Ikzf1 associates with Foxp3 to repress gene expression in Treg cells and limit autoimmunity and anti-tumor immunity