Loss of Ezh2 cooperates with Jak2V617F in the development of myelofibrosis in a mouse model of myeloproliferative neoplasm

Enhancer invasion shapes MYCN dependent transcriptional amplification in neuroblastoma

KDM4B epigenetically protects against obesity and metabolic dysfunction

Srf destabilizes cell identity

Safeguard function of PU.1 shapes the inflammatory epigenome of neutrophils

The Transcription factor Zeb2 ia required to maintain tissue-specific identities of macrophages

E-C coupling structural protein junctophilin-2 encodes a stress-adaptive transcription regulator

Molecular function of stress-dependent epigenetic regulator ATF7 in paternal inheritance of dietary effect on offspring phenotype

CD69+ memory T lymphocytes of the bone marrow and spleen express the signature transcripts of tissue-resident memory T lymphocytes

Stellate cells, hepatocytes and endothelial cells imprint the Kupffer cell identity on monocytes colonizing the liver macrophage niche

LMO3 reprogramms viseral adipocyte metabolism during obesity

Transcriptional down-regulation of metabolic genes by Gdown1 ablation induces quiescent cell re-entry into the cell cycle

Distinct signature, origin and dynamics of macrophages in the peripheral and central nervous system

IL-27 driven transcriptional network identifies regulators of IL-10 expression across T helper cell subsets

Primordial germ cells identified as one potential cell of origin of MYC rhabdoid tumors

Tumor educated Gr1+CD11b+ myeloid cells instigate breast cancer cells plasticity, and trigger metastasis via OSM/IL6 JAK signaling

An alternative pluripotent state confers interspecies chimaeric competency

Single-cell sequencing reveals PDFGRα+ stromal cell subpopulations that promote proacinar differentiation in embryonic salivary gland organoids

Lymphatic endothelial cell identity is controlled by a GATA2 bound enhancer

Hepatic p53 protein level governs liver s sensitivity to drug-induced liver injury