MYC dependent mRNA translation shapes gene expression and cell biology

Genome-wide characterization of BCL6/STAT5-switch target genes identifies reprogramming of DNA damage response as a novel branch of RAC1/PAK1 signalling

Systematic functional characterization of BAF mutations yields novel intra-complex synthetic lethalities [ATAC-Seq]

Systematic functional characterization of BAF mutations yields novel intra-complex synthetic lethalities [ChIP-Seq]

Systematic functional characterization of BAF mutations yields novel intra-complex synthetic lethalities [RNA-Seq]

Targeting FGFR overcomes EMT-mediated resistance in EGFR mutant non-small cell lung cancer

Reprogramming of Tumor-infiltrating Immune Cells in Early Stage of NSCLC

CUT&Tag for efficient epigenomic profiling of small samples and single cells

Non-coding and coding transcriptional profiles are significantly altered in pediatric Retinoblastoma tumors

CRISPR screens are feasible in TP53 wild-type cells

miR-450a acts as a tumor suppressor in ovarian cancer by readjusting energy metabolism

Gene Specific Activation Driven by Small Molecules

Genome wide CRISPR screen for Venetoclax resisatnce in MOLM13 cells using Y. Kosuke library

Genome wide CRISPR screen for Venetoclax resisatnce in MOLM13 cells using Brunello library

Hominid-specific transposable elements and KRAB-ZFPs facilitate human embryonic genome activation and transcription in naïve hESCs [RNA-seq]

Hominid-specific transposable elements and KRAB-ZFPs facilitate human embryonic genome activation and transcription in naïve hESCs [ChIP-seq]

Hominid-specific transposable elements and KRAB-ZFPs facilitate human embryonic genome activation and transcription in naïve hESCs [ATAC-seq]

Transcriptome profiles in MRC5 and CS1AN cell lines upon UV irradiation