cGAS/STING drives ageing-related inflammation and neurodegeneration

Adamantinomatous craniopharyngioma cyst fluid can trigger inflammatory activation of microglia to damage the hypothalamic neurons by inducing the production of β-amyloid

Single Cell Transcriptomic Profiling of MYBPC3-associated Hypertrophic Cardiomyopathy Across Species Reveals Conserva-tion of Biological Process but Not Gene Expression

XCR1+ type 1 conventional dendritic cells drive liver pathology in Non-Alcoholic Steatohepatitis.

The transcriptional and regulatory identity of erythropoietin producing cells

Imaging and multi-omics datasets converge to define different neural progenitor origins for ATRT-SHH subgroups

Rational design of a SOCS1-edited tumor infiltrating lymphocyte therapy for solid tumors using CRISPR/Cas9 screens

Systematic Single Cell Pathway Analysis (SCPA) reveals novel pathways engaged during early T cell activation

YAP/TAZ activity in stromal cells prevents ageing by controlling cGAS/STING

Activated CD4 T cells in tuberculosis express OX40, a target for host-directed immunotherapy

BMPER: a novel adipose progenitor marker and adipogenic modulator

Choroid plexus mast cells drive tumor-associated hydrocephalus

G-CSF SECRETED BY EPIGENETICALLY REPROGRAMMED MUTANT IDH1 GLIOMA STEM CELLS, REVERSES THE MYELOID CELLS'-MEDIATED IMMUNOSUPPRESSIVE TUMOR MICROENVIRONMENT

IL-17 activates dermal reticular fibroblasts to promote neutrophil recruitment and host defense

Titration of RAS alters senescent state and influences tumour initiation

Genome editing by dual nucleases records deep lineage hierarchy with high fidelity.

Transcriptomics of skin reveal potential molecular mechanisms of psoriasis

Lipid-accumulated reactive astrocytes promote seizure activity in epilepsy

HuPSA and MoPSA Atlases Reveal Novel Cell Populations and Lineage Plasticity in Prostate Cancer at Single-Cell Level

Durable Alterations of Hematopoiesis and Chromatin post-COVID-19 [MultiomeATAC-seq]