Single-cell profiling of histone modifications and transcription in developmental systems with EpiDamID

ARID1A and PI3-Kinase pathway mutations in the endometrium drive epithelial transdifferentiation and collective invasion

Satb1 integrates DNA sequence, shape, motif density and torsional stress to selectively bind a subset of putative targets in nucleosome-dense regions of the genome

An evolutionarily conserved function of polycomb silences the MHC class I antigen presentation pathway and enables immune evasion in cancer [ChIP-Seq]

An evolutionarily conserved function of polycomb silences the MHC class I antigen presentation pathway and enables immune evasion in cancer

Che-1/AATF-induced transcriptionally active chromatin promotes cell proliferation in Multiple Myeloma

SWI/SNF inactivation in the endometrial epithelium leads to loss of epithelial integrity

Single-cell profiling of histone modifications and transcription in developmental systems with EpiDamID [bulk ChIP-seq]

CRISPR-ChIP to identify mechanisms of chromatin regulation [ChIP-seq]

Stepwise activities of mSWI/SNF family chromatin remodeling complexes direct T cell activation and exhaustion [ATAC-seq]

Stepwise activities of mSWI/SNF family chromatin remodeling complexes direct T cell activation and exhaustion

Cooperative super-enhancer inactivation caused by heterozygous loss of CREBBP and KMT2D skews B-cell fate decisions and accelerates development of T-cell depleted lymphomas.