Molecular and functional heterogeneity of IL-10-producing CD4+ T cells

Treatment of a metabolic liver disease by in vivo prime editing in mice

In vivo adenine base editing of PCSK9 in mice and macaques reduces LDL-cholesterol levels [amplicon-seq]

In vivo adenine base editing of PCSK9 in mice and macaques reduces LDL-cholesterol levels

Uncovering mechanisms of early human lineage specification by CRISPR/Cas9-mediated genome editing

Promoter of lncRNA gene *PVT1* is a tumor suppressor DNA element

Genome editing reveals a role for OCT4 in human preimplantation development [MiSeq]

A pliable mediator acts as a functional, rather than an architectural bridge, between promoters and enhancers

ASPSCR1-TFE3 reprograms transcription by organizing enhancers around hexameric VCP

SPLICER: A Highly Efficient Base Editing Toolbox That Enables in vivo Exon Skipping For Targeting Alzheimer’s Disease

SPLICER: A Highly Efficient Base Editing Toolbox That Enables in vivo Exon Skipping For Targeting Alzheimer’s Disease [miSeq]

TIME-Seq Enables Scalable and Inexpensive Epigenetic Age Predictions.

Phosphatidylinositol 3-Kinase (PI3K) delta blockade increases genomic instability in B cells

Targeting Duchenne Muscular Dystrophy by Skipping DMD Exon 45 with Base Editors

Trimannose-coupled antimiR-21 for macrophage-targeted inhalation treatment of acute inflammatory lung damage

In vivo CRISPR base editing for treatment of Huntington’s disease

Base editor induced mutation spectrum in GFP, human ATP1a1, human TP53BP1 and murine MyoD

HNRNPA2B1 regulates alternative RNA processing in the nervous system and accumulates in granules in ALS IPSC-derived motor neurons

Active DNA demethylation promotes cell fate specification and the DNA damage response

Small and large RNA sequencing of mouse livers receiving small hairpin RNAs