Glutamine antagonist DRP-104 suppresses tumor growth and enhances response to checkpoint blockade in KEAP1 mutant lung cancer

An Anterior Second Heart Field Enhancer Regulates the Gene Regulatory Network of the Cardiac Outflow Tract

Hedgehog signaling affects platelet-derived growth factor signaling mediated alveolar septum formation during postnatal lung development [bulk RNA-seq]

Apolipoprotein E4 Is Associated with a Distinct Transcriptomic Profile of Hippocampal Neurons and Attenuates Their Maturation In Vitro

Clonal lineage tracing reveals shared origin of conventional and plasmacytoid dendritic cells

PRC1 Sustains the Memory of Neuronal Fate Independent of PRC2 Function

The volume regulated anion channel LRRC8C suppresses T cell function by regulating cyclic dinucleotide transport and STING-p53 signaling

Combined Inhibition of SHP2 and CXCR1/2 Promotes Anti-Tumor T Cell Response in NSCLC

Targeting the Atf7ip-Setdb1 complex augments anti-tumor immunity by boosting tumor immunogenicity

Neural Cell Adhesion Molecule (NCAM-1) is Required for Ventricular Conduction System Development

β-carotene conversion to vitamin A delays atherosclerosis progression by decreasing hepatic lipid secretion in mice

RNA seq to compare gene expression profiles between Npm1 WT and Npm1 knockdown cells

PD-L1 Engagement on T cells Promotes Self-tolerance and Suppression of Neighboring Macrophages and Effector T cells in Cancer

RNA-seq to compare gene expression profiles between Asf1a WT and Asf1a KO cells

In vitro and in vivo epigenome-wide CRISPR screens in mouse KrasG12D/P53-/- (KP) lung adenocarcinoma model

Dpy30 Is Critical for Maintaining the Identity and Function of Adult Hematopoietic Stem Cells