Pharmaceutical reversal of Dkk1-induced LRP6 endocytosis prevents cancer cachexia and prolongs survival

Ablation of the Sost gene prevents hallmarks of calcific aortic valve disease in a high-cholesterol mouse model

Cytokine-sensing primary enhancer cluster launches secondary enhancers to activate multi-gene locus [4C-seq]

Cytokine-sensing primary enhancer cluster launches secondary enhancers to activate multi-gene locus [Hi-C]

MRAP mediated adipocyte differentiation by thymic mesenchymal stromal cells contributes to thymic involution

The role of cadherin-11 in Unx/AngII induced kidney injury [Huffstater_AA]

The role of cadherin-11 in Unx/AngII induced kidney injury [Huffstater_Unx]

ChIP-DIP maps binding of hundreds of proteins to DNA simultaneously and identifies diverse gene regulatory elements

RNA sequencing of wild type or calcineurin-deficient mouse bone marrow-derived dendritic cells stimulated with or without lipoarabinomannan (LAM) from Mycobacterium tuberculosis Aoyama-B

CUT&RUN to map WT1 binding in M15 cell lines that are genome edited for the KTS isoforms.

Bulk RNA sequencing and analysis of sorted Common Lymphoid Progenitor (CLP) cells from WT, Notch1+/-, and Notch1+/ΔTAD adult mouse bone marrow

Epithelial deletion of CUL4B increased myeloid-derived suppressor cells-mediated immunosuppression to promote ApcMin/+ tumor formation

Setd2 reprograns lipid metabolism for the resolution of inflammation via H3K36me3 modification

Transcriptome analysis of ear cartilage lipochondrocytes at multiple stages of differentiation.

High-mobility group box1 peptide ameliorates bronchopulmonary dysplasia (BPD) via suppressing inflammation and fibrosis in a mouse model.

Metastasis of colon cancer requires Dickkopf-2 to generate cancer cells with Paneth cell properties

Metastasis of colon cancer requires Dickkopf-2 to generate cancer cells with Paneth cell properties [RNA-seq]

H3K27me3 regulates macrophage cytokine transcription and impacts on Collagen Induced Arthritis [ATAC-Seq]

H3K27me3 regulates macrophage cytokine transcription and impacts on Collagen Induced Arthritis [ChIP-Seq]

To explore the functional consequences of ZBTB7A Overexpression in rodent OFC astrocytes in the context of a mild stressor