Polycomb Mediated Chromatin Organization Reveals Transcriptional Silencers Required for Embryonic Development

CTCF Functions as an Insulator for Somatic Genes and a Structural Regulator for Pluripotent Genes during Reprogramming

RNA interactions are essential for proper CTCF function

A distal super enhancer mediates estrogen-dependent mouse uterine–specific gene transcription of Insulin-like growth factor 1 (Igf1)

H4K20me3 methyltransferase SUV420H2 shapes the three-dimensional chromatin landscape of pluripotent embryonic stem cells

Defining the relative and combined contribution of CTCF and CTCFL to genomic regulation

Histone 1 deficiency drives lymphomagenesis through disruption of 3D chromatin architecture

Balancing cohesin eviction and retention prevents aberrant chromosomal interactions, Polycomb-mediated repression, and X-inactivation

CTCF Mediates Dosage and Sequence-context-dependent Transcriptional Insulation through Formation of Local Chromatin Domains

CRISPR and biochemical screens identify MAZ as a co-factor in CTCF-mediated insulation at Hox clusters

Architectural role of cell-fate-instructive transcription factor MyoD in orchestrating 3D genome organization in muscle cells.

Hijacking of transcriptional condensates by endogenous retroviruses

Single-cell transcriptome and 3D genome atlas of the developing mouse brain

NEURON-SPECIFIC CHROMOSOMAL MEGADOMAIN ORGANIZATION IS ADAPTIVE TO RECENT RETROTRANSPOSON EXPANSIONS

Tcf1 is essential for initiation of oncogenic Notch1-driven chromatin topology.

SETDB1/NSD dependent H3K9me3/H3K36me3 dual heterochromatin maintains gene expression profiles by bookmarking poised enhancers

Topologically Associating Domain Boundaries are Required for Normal Genome Function

The spliceosome component Usp39 controls B cell development by regulating immunoglobulin gene rearrangement

NicE-C efficiently reveals open chromatin associated chromosome interactions at high resolution

TCF-1 mediates 3D genome reconfiguration during T cell development