Droplet-based genome-wide forward genetic screening of astrocyte-microglia communication mechanisms

Analysis of diversity in barcoded plasmid library

Analysis of diversity in barcoded virus library

Barcoded viral tracing of single-cell interactions in CNS inflammation

RABID barcodes from naive astrocyte networks

RABID transcriptome from peak EAE astrocyte networks

RABID transcriptome from naive astrocyte networks

RABID barcodes from peak EAE astrocyte networks

Microglial Semaphorin4D and astrocyte PlexinB1-B2 knockdown in EAE

RABID barcodes from priming EAE astrocyte networks

RABID transcriptome from priming EAE astrocyte networks

Genome-wide analysis of the transcriptional profile of TRAIL+LAMP1+ astrocytes and LAMP1+ astrocytes during EAE in Aldh1l1CreERT2-TdTomato mice by scRNA-seq

Genome-wide analysis of the transcriptional profile of WT and Lamp1 KD astrocytes during EAE in B6 mice

Analysis of astrocyte interferon gamma signaling during EAE.

Analysis of microglia responses following astrocyte knockdown of interferon gamma signaling during EAE.

Genome-wide analysis of the transcriptional profile of astrocytes during EAE in Gfap-TdTomato mice by scRNA-seq.

IFN-gamma+ NK cells control TRAIL+ anti-inflammatory astrocytes

Genome-wide analysis of DNA methylation profile in astrocytes isolated from naïve mice or EAE mice transduced with astrocyte-specific Mafg-targeting or non-targeting lentiviruses [WGBS]

Genome-wide analysis of MAFG binding in astrocytes during EAE [ChIP-seq]

Genome-wide analysis of chromatin profile in astrocytes isolated from EAE mice transduced with astrocyte-specific Mafg-targeting or non-targeting lentiviruses [ATAC-seq]