Physical interaction with Spo11 mediates the localisation of Mre11 to chromatin in meiosis and promotes its nuclease activity

Spo11 generates gaps through concerted cuts at sites of topological stress [Top2]

Spo11 generates gaps through concerted cuts at sites of topological stress [dDSB]

Spo11 generates gaps through concerted cuts at sites of topological stress

Comparison of expression profiles of Ba/F3 cells transduced with human CALR or human CALR + Type 1 mutation (hCALR-del52) by RNA-seq