Self-reporting transposons enable simultaneous readout of gene expression and transcription factor binding in single cells

Full-length dystrophin restoration via targeted genomic integration by AAV-CRISPR in a humanized mouse model of Duchenne muscular dystrophy

Genome-wide maps of gV sPLA2 binding sites in Raw 264.7 cells

The Dynamic Epigenetic Landscape of the Retina During Development, Reprogramming, and Tumorigenesis

UTX and 53BP1 co-regulate genetic programs for neural differentiation of human embryonic stem cells

Activation of HOTTIP lncRNA perturbs HSC function leading to AML like disease

HOXBLINC is aberrantly expressed in acute myeloid leukemia and functions as a potent oncogenic long non-coding RNA in leukemogenesis

Aberrant chromatin landscape upon loss of the H3.3 chaperone Daxx leads to Pu.1-mediated neutrophilia and inflammation [ATAC-Seq]

A neutropenia-associated transcription factor mutation differentially impacts target genes in the cell-states traversed during granulocyte specification and commitment

Promoter capture Hi-C identifies long-range promoter contact dynamics in response to diet and the development of non-alcoholic fatty liver disease

ChIP-seq and RNA-seq analysis of histone Kcr in the embryonic forebrain and neural stem/progenitor cells.

A conserved noncoding locus modulates random monoallelic Xist expression across a TAD boundary

Genome-wide methyl-cytosine competition by DNMT and TET

Histone 3 K9 and K27 acetylation of enhancers in response to thyroid hormone

Tox reinforces the phenotype and longevity of exhausted T-cells in chronic viral infection

Escape of hair follicle stem cells from a defective niche

ETV2 primes hematoendothelial gene enhancers prior to hematoendothelial fate commitment

Genome-wide chromatin analyses of liver cells upon YAP induction [Liver_ChIPSeq_LapTTA]

Genome-wide chromatin analyses and RNA-seq of liver cells upon YAP induction

Integrative single-cell chromatin and transcriptome profiling uncovers cell-type specific regulatory interactions