An autocrine signaling circuit in hepatic stellate cells underlies advanced fibrosis in non-alcoholic steatohepatitis

A contamination focused approach for optimizing the single-cell RNA-seq experiment

Deep dynamical modelling of developmental trajectories with temporal transcriptomics

Longitudinal single-cell transcriptional dynamics throughout neurodegeneration in SCA1

Alveolar differentiation drives resistance to KRAS inhibition in lung adenocarcinoma

Single-cell and spatial profiling identify three response trajectories to pembrolizumab and radiation therapy in triple negative breast cancer

Open-ST: High-resolution spatial transcriptomics in 3D

Tabula Muris

Tabula Muris Senis

Rescuing voluntary motor behavior in a Parkinson´s disease model by aCRISPR mediated reprogramming of striatal astrocytes into induced GABAergic neurons

Single cell RNA seq of hepatic and renal p16 positive cells

Single-cell RNA sequencing of pancreatic islets from obese mice with different diabetes risk reveals diabetes-susceptible β cell clusters

Activity-dependent modulation of synapse-regulating genes in astrocytes

Single-cell RNA sequencing reveals a role of Phf2 in promoting the exit of postnatal neural stem cell from shallow quiescence.

Partial reprogramming restores youthful gene expression through transient suppression of cell identity

Reconstruction of dynamic regulatory networks reveals signaling-induced topology changes associated with germ layer specification

Heme-Nrf2 signaling shifts myeloid differentiation

Heme signaling shifts myeloid differentiation in GM-CSF BM cell cultures

Heme exposure shifts shifts myeloid differentiation in bone marrow derived mixed cell cultures.

Deviated myeloid differentiation in SCD mice under heme stress I.