Spatial proteogenomics reveals distinct and evolutionarily-conserved hepatic macrophage niches (single cells)

Spatial proteogenomics reveals distinct and evolutionarily-conserved hepatic macrophage niches

Neuroinflammatory astrocyte subtypes in the mouse brain

Single cell RNA-seq of forebrain cells isolated from wild-type mouse, rat, and chimeric mouse

Assessment of Spatial Genomics for Oncology Discovery

Neonatal imprinting of mesenteric lymph node stroma modulates tolerogenic properties of dendritic cells [scRNA-seq]

Neonatally imprinted mesenteric lymph node stromal cell subsets induce tolerogenic dendritic cells

A neutropenia-associated transcription factor mutation differentially impacts target genes in the cell-states traversed during granulocyte specification and commitment

Opposing Wnt signals regulate cervical squamocolumnar homeostasis and emergence of metaplasia

Single-cell RNA-sequencing of full thickness mouse skin during anagen and telogen

mouse lung single cell RNA-seq

Senescence rather than apoptosis of alveolar progenitor cells drives pulmonary fibrosis (mouse scRNAseq)

Senescence rather than apoptosis of alveolar progenitor cells drives pulmonary fibrosis

Developmental Dieldrin Exposure Alters DNA Methylation at Genes Related to Dopaminergic Neuron Development and Parkinson’s Disease in Mouse Midbrain

Antigen-driven EGR2 expression is required for exhausted CD8+ T cell stability and maintenance

Time series single cell transcriptomics of cardiac inflammation after myocardial infarction in mice

Single cell RNAseq profiling of Tbx1 function in adult post myocardial infarction hearts [scRNA-seq]

Epigenetic adaptation prolongs photoreceptor survival during retinal degeneration

Tbx1 promotes neo-lymphangiogenesis and constraints the immune response to facilitate repair.

Cytotoxic CNS-associated T cells drive axon degeneration in aging and myelin disease