Uninfected, untreated, control organoids

Uninfected, 4-hydroxytamoxifen treated, control organoids

Dual guide RNA targeting Ppard infected, untreated, control organoids, 1

Dual guide RNA targeting Ppard infected, untreated, control organoids, 2

Ppard mutant organoid line 1: transduced with Ppard-targetting dual guide RNAs, treated with 4-hydroxytamoxifen, 1

Ppard mutant organoid line 1: transduced with Ppard-targetting dual guide RNAs, treated with 4-hydroxytamoxifen, 2

Dual guide RNA targeting Cdx1 infected, untreated, control organoids

Cdx1 mutant organoid line 1: transduced with Ppard-targetting dual guide RNAs, treated with 4-hydroxytamoxifen