Klebsiella pneumoniae. This organism is the most medically important organism within the genus
Klebsiella. It is an environmental organism found in water, soil, and on the surface of plants. Several strains have been isolated from plant tissues and are nitrogen-fixing endophytes that may be a source of nitrogen for the plant. Other
More...strains can become opportunistic pathogens which infect humans, and typically causes hospital-acquired infections in immunocompromised patients. Major sites of infection include the lungs, where it causes a type of pneumonia, and urinary tract infections. Klebsiella can also enter the bloodstream (bacterimia) and cause sepsis. The pathogen can also infect animals and cause inflammation of the uterus in horses as well as more generalized infections in other mammals.This organism expresses numerous pathogenicity factors, including multiple adhesins, capsular polysaccharide, siderophores, and lipopolysaccharide for the evasion of host defenses. Capsular polysaccharide (K antigen), for example, prevents phagocytosis. The multiple antibiotic resistance genes carried on the chromosome inhibit efforts to clear the organism from infected patients via antibiotic use. Many of the virulence factors remain to be elucidated. Less...- MuDoGeR: Multi-Domain Genome recovery from metagenomes made easy. Rocha U, et al. Mol Ecol Resour 2024 Feb
- Cross-contamination of carbapenem-resistant Gram-negative bacteria between patients and the hospital environment in the first year of a newly built surgical ward. Boutin S, et al. J Hosp Infect 2024 Feb
- CTX-M-15/27-positive Escherichia coli and VIM-2-producing Pseudomonas putida in free-living pigeons (Columba livia) in Tunisia. Souguir M, et al. J Glob Antimicrob Resist 2024 Mar
- First detection in Spain of NDM-1-producing Pseudomonas aeruginosa in two patients transferred from Ukraine to a university hospital. Hernández-García M, et al. J Glob Antimicrob Resist 2024 Mar
- Clinical, microbiological and genomic characterization of Gram-negative bacteria with dual carbapenemases as identified by rapid molecular testing. Mushtaq A, et al. JAC Antimicrob Resist 2024 Feb
- Dynamic within-host cefiderocol heteroresistance caused by bla(SHV-12) amplification in pandrug-resistant and hypervirulent Klebsiella pneumoniae sequence type 11. Liu C, et al. Drug Resist Updat 2024 Mar
- In-patient evolution of a high-persister Escherichia coli strain with reduced in vivo antibiotic susceptibility. Parsons JB, et al. Proc Natl Acad Sci U S A 2024 Jan 16
- Genomic and epidemiological insight of an outbreak of carbapenemase-producing Enterobacterales in a Portuguese hospital with the emergence of the new KPC-124. Manageiro V, et al. J Infect Public Health 2024 Mar
- Genome-centric analyses of 165 metagenomes show that mobile genetic elements are crucial for the transmission of antimicrobial resistance genes to pathogens in activated sludge and wastewater. Abdulkadir N, et al. Microbiol Spectr 2024 Mar 5
- Molecular identification and whole genome sequence analyses of methicillin-resistant and mastitis-associated Staphylococcus aureus sequence types 6 and 2454 isolated from dairy cows. Rahman MH, et al. J Genomics 2024
- Draft genome sequences of Bacillus licheniformis strains MEZBL63 and MEZBL64 harboring the lichenysin toxin operon isolated from livestock in South Africa. El Zowalaty ME, et al. Microbiol Resour Announc 2024 Mar 12
- Emergence of tet(X4)-positive Enterobacterales in retail eggs and the widespread of IncFIA(HI1)-HI1A-HI1B(R27) plasmids carrying tet(X4). Yue C, et al. Int J Food Microbiol 2024 Apr 2
- ST218 Klebsiella pneumoniae became a high-risk clone for multidrug resistance and hypervirulence. Yang P, et al. BMC Microbiol 2024 Feb 12
- Establishment of a non-Westernized gut microbiota in men who have sex with men is associated with sexual practices. Huang KD, et al. Cell Rep Med 2024 Mar 19
- Bacterial and Candida Colonization of Neonates in a Regional Hospital in South Africa. Mabena FC, et al. Pediatr Infect Dis J 2024 Mar 1
- Occurrence and mechanisms of tigecycline resistance in carbapenem- and colistin-resistant Klebsiella pneumoniae in Thailand. Chirabhundhu N, et al. Sci Rep 2024 Mar 3
- Occurrence and persistence of multidrug-resistant Enterobacterales isolated from urban, industrial and surface water in Monastir, Tunisia. Ncir S, et al. Sci Total Environ 2024 May 20
- Molecular epidemiology and mechanisms of carbapenem and colistin resistance in Klebsiella and other Enterobacterales from treated wastewater in Croatia. Puljko A, et al. Environ Int 2024 Mar
- Cataloging the phylogenetic diversity of human bladder bacterial isolates. Du J, et al. Genome Biol 2024 Mar 21
- Draft genome sequences of clinical mastitis-associated Enterococcus faecalis and Enterococcus faecium carrying multiple antimicrobial resistance genes isolated from dairy cows. Rahman MH, et al. J Glob Antimicrob Resist 2024 May 23
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Reference genome:  
Klebsiella pneumoniae subsp. pneumoniae HS11286
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