Genome

Pan troglodytes (chimpanzee) The chimpanzee genome sequence is an important tool in understanding primate evolution Lineage: Eukaryota[15558]; Metazoa[7784]; Chordata[3583]; Craniata[3548]; Vertebrata[3548]; Euteleostomi[3503]; Mammalia[873]; Eutheria[699]; Euarchontoglires[338]; Primates[190]; Haplorrhini[138]; Catarrhini[64]; Hominidae[7]; Pan[2]; Pan troglodytes[1]

Pan troglodytes, or chimpanzee, is a primate very closely related to humans. The chimpanzee and other apes are most closely related to humans, followed by Old World monkeys; including the rhesus macaque and baboon. The chimpanzee is an important model to study biology, disease, and evolution. Research with Pan troglodytes has provided More...important insights into cognition, AIDs, hepatitis, diabetes, and other diseases.The genome sequence of the chimpanzee provides an important resource for comparative sequence analysis. Differences between chimpanzee and human genomes will help define the genetic basis of traits that distinguish the human species from other primates. The Pan troglodytes diploid genome is organized in 23 pairs of autosomes and two sex chromosomes. Less...

Summary Sequence data:  genome assemblies: 10; sequence reads: 5  (See  Genome Assembly and Annotation report) Statistics:  median total length (Mb): 3101.54  median protein count: 80679  median GC%: 40.7 NCBI Annotation Release:  107 Publications (limited to 20 most recent records) Structurally divergent and recurrently mutated regions of primate genomes. Mao Y, et al. bioRxiv 2023 Mar 7 A mitogenomic phylogeny of living primates. Finstermeier K, et al. PLoS One 2013 Comparative analysis of chimpanzee and human Y chromosomes unveils complex evolutionary pathway. Kuroki Y, et al. Nat Genet 2006 Feb Initial sequence of the chimpanzee genome and comparison with the human genome. Chimpanzee Sequencing and Analysis Consortium Nature 2005 Sep 1 Conservation of Y-linked genes during human evolution revealed by comparative sequencing in chimpanzee. Hughes JF, et al. Nature 2005 Sep 1 DNA sequence and comparative analysis of chimpanzee chromosome 22. Watanabe H, et al. Nature 2004 May 27 Recent African origin of modern humans revealed by complete sequences of hominoid mitochondrial DNAs. Horai S, et al. Proc Natl Acad Sci U S A 1995 Jan 17 Man's place in Hominoidea revealed by mitochondrial DNA genealogy. Horai S, et al. J Mol Evol 1992 Jul Comparisons of ape and human sequences that regulate mitochondrial DNA transcription and D-loop DNA synthesis. Foran DR, et al. Nucleic Acids Res 1988 Jul 11 A comparison of the small ribosomal RNA genes from the mitochondrial DNA of the great apes and humans: sequence, structure, evolution, and phylogenetic implications. Hixson JE, et al. Mol Biol Evol 1986 Jan More...  Representative (genome information for reference and representative genomes) Reference genome:   Pan troglodytes NHGRI_mPanTro3-v2.0_pri Submitter: National Human Genome Research Institute, National Institutes of Health Loc Type Name RefSeq INSDC Size (Mb) GC% Protein rRNA tRNA Other RNA Gene Pseudogene master WGS - JAQQLN000000000.2 3,177.74 40.5 - - - - - - Chr 1 NC_072398.2 CM054434.2 231.3 41.8 10,724 113 163 2,281 4,241 647 Chr 2 NC_086015.1 CM068905.1 201.58 39.6 6,758 1 4 1,563 2,294 445 Chr 3 NC_072401.2 CM054437.2 191.67 38.3 4,452 - 1 1,197 1,783 340 Chr 4 NC_072402.2 CM054438.2 178.96 39.6 4,462 - 18 1,243 1,995 371 Chr 5 NC_072403.2 CM054439.2 183.32 39.3 5,296 1 156 1,464 2,431 441 Chr 6 NC_072404.2 CM054440.2 174.65 40.5 5,483 - 17 1,316 2,115 381 Chr 7 NC_072405.2 CM054441.2 155.69 40.1 3,856 - 6 1,110 1,703 298 Chr 8 NC_072406.2 CM054442.2 146.29 41.1 5,010 - 3 966 1,609 273 Chr 9 NC_072407.2 CM054443.2 136.99 41.4 6,324 - 13 1,096 2,311 375 Chr 10 NC_072408.2 CM054444.2 140.16 40.5 5,967 - 7 1,254 1,999 314 Chr 11 NC_072409.2 CM054445.2 118.86 41.3 4,547 1 3 945 1,535 279 Chr 12 NC_072410.2 CM054446.2 122.85 40.5 3,737 1 4 1,083 1,357 205 Chr 13 NC_072411.2 CM054447.2 144.48 39.2 4,350 1 4 1,068 1,402 257 Chr 14 NC_072412.2 CM054448.2 120.15 38.5 2,190 24 4 826 1,026 210 Chr 15 NC_072413.2 CM054449.2 104.7 39.8 3,345 22 19 984 1,497 269 Chr 16 NC_072414.2 CM054450.2 93.85 41.6 3,610 - 9 991 1,404 262 Chr 17 NC_072415.2 CM054451.2 90.7 39.4 1,790 44 1 566 841 154 Chr 18 NC_072416.2 CM054452.2 94.53 43.8 4,731 - 28 923 1,582 189 Chr 19 NC_072417.2 CM054453.2 99.6 44.1 5,960 - 33 1,191 2,079 256 Chr 20 NC_072418.2 CM054454.2 68.09 46.2 6,429 - 8 950 2,033 198 Chr 21 NC_072419.2 CM054455.2 78.12 42.4 2,643 1 - 696 1,016 131 Chr 22 NC_072420.2 CM054456.2 51.35 39.9 1,098 8 - 388 537 106 Chr 23 NC_086016.1 CM068906.1 59.52 42.7 2,619 11 1 561 896 123 Chr X NC_072421.2 CM054457.2 153.9 39.5 3,663 1 2 793 1,778 424 Chr Y NC_072422.2 CM054458.2 36.45 41.3 255 3 - 126 314 137 MT NC_001643.1 - 0.02 43.7 13 2 22 - 37 - Chromosomes Click on chromosome name to open Genome Data Viewer External Resources Washington University Genome Sequencing Center Broad Institute CHGCS CHORI BAC library Ensembl Great Ape Genome Project IPBIR KRIBB National Primate Research Centers Primate Cytogenetics UCSC browser White Paper #1 White Paper #2