Genome

Trichomonas vaginalis This protozoan parasite is the causal agent of human trichomoniasis, a sexually transmitted infection. Lineage: Eukaryota[15557]; Metamonada[18]; Parabasalia[5]; Trichomonadida[3]; Trichomonadidae[3]; Trichomonas[3]; Trichomonas vaginalis[1]

Trichomonas vaginalis is a flagellated protozoan parasite that is the causal agent of human trichomoniasis. This infection is typically transmitted by sexual intercourse and accounts for approximately 170 million cases per year worldwide, making it one of the most prevalent non-viral sexually transmitted diseases in the world. This is an extracellular More...parasite that adheres to the epithelium of the urogenital tract of both men and women and is responsible for urethritis, prostatitis or vaginitis, respectively. In North America alone, T. vaginalis is responsible for approximately 5 million cases of vaginitis annually. Furthermore, this organism has been associated with increased risk of HIV infection. T. vaginalis appears to exist only as a trophozoite which divides by binary fission. Because T. vaginalis is anaerobic, it does not contain mitochondria in its cytoplasm. Instead, it possesses specialized granule-like organelles called the hydrogenosomes which are involved in the parasite's carbohydrate metabolism. A new predicted function for the hydrogenosomes recently revealed by the genome sequence of T. vaginalis is involvement in aminoacid metabolism. Less...

Summary Sequence data:  genome assemblies: 3; sequence reads: 1  (See  Genome Assembly and Annotation report) Statistics:  median total length (Mb): 176.42  median protein count: 65985  median GC%: 32.7104 Publications (limited to 20 most recent records) Draft genome sequence of the sexually transmitted pathogen Trichomonas vaginalis. Carlton JM, et al. Science 2007 Jan 12  Representative (genome information for reference and representative genomes) Reference genome:   Trichomonas vaginalis G3 Submitter: New York University Loc Type Name RefSeq INSDC Size (Mb) GC% Protein rRNA tRNA Other RNA Gene Pseudogene Chr I NC_067203.1 CM044617.1 27.73 32.6 11,195 1 103 - 13,526 - Chr II NC_067204.1 CM044618.1 26.08 32.6 10,463 63 42 - 12,503 - Chr III NC_067205.1 CM044619.1 27.74 32.5 10,919 29 78 - 13,109 - Chr IV NC_067206.1 CM044620.1 40.21 32.8 15,719 36 89 - 19,579 - Chr V NC_067207.1 CM044621.1 34.66 32.8 13,923 14 119 - 16,626 - Chr VI NC_067208.1 CM044622.1 20.33 32.8 8,536 - 68 - 10,137 - Un - . - 4.72 33.4 1,535 - 1 - 2,676 1,140 Chromosomes Click on chromosome name to open Genome Data Viewer External Resources Dalhousie University, Dr. Roger Laboratory TIGR