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    SMAD3 SMAD family member 3 [ Tursiops truncatus (common bottlenose dolphin) ]

    Gene ID: 101339651, updated on 8-Mar-2024

    Summary

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    Gene symbol
    SMAD3
    Gene description
    SMAD family member 3
    See related
    EnsemblRapid:ENSTTRG00000003030
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Tursiops truncatus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti; Delphinidae; Tursiops
    Orthologs
    human mouse all
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    Genomic context

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    See SMAD3 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    102 current mTurTru1.mat.Y (GCF_011762595.1) 2 NC_047035.1 (108997796..109117627)
    101 previous assembly NIST Tur_tru v1 (GCF_001922835.1) Unplaced Scaffold NW_017842395.1 (12998208..13031415)

    Chromosome 2 - NC_047035.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC109552329 Neighboring gene golgin subfamily A member 7-like Neighboring gene uncharacterized LOC117311106 Neighboring gene alpha and gamma adaptin binding protein Neighboring gene uncharacterized LOC109552341 Neighboring gene IQ motif containing H Neighboring gene chromosome 2 C15orf61 homolog

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables I-SMAD binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in BMP signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in SMAD protein signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in anatomical structure morphogenesis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell differentiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in transforming growth factor beta receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of heteromeric SMAD protein complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    mothers against decapentaplegic homolog 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Tursiops truncatus Annotation Release 102 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference mTurTru1.mat.Y Primary Assembly

    Genomic

    1. NC_047035.1 Reference mTurTru1.mat.Y Primary Assembly

      Range
      108997796..109117627
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_033851868.1 → XP_033707759.1  mothers against decapentaplegic homolog 3 isoform X1

      UniProtKB/TrEMBL
      A0A6J3QZT8
      Related
      ENSTTRP00000032224.1, ENSTTRT00000032037.1
      Conserved Domains (2) summary
      cd10491
      Location:8 → 132
      MH1_SMAD_2_3; N-terminal Mad Homology 1 (MH1) domain in SMAD2 and SMAD3
      cd10985
      Location:224 → 414
      MH2_SMAD_2_3; C-terminal Mad Homology 2 (MH2) domain in SMAD2 and SMAD3

    2. XM_033851869.1 → XP_033707760.1  mothers against decapentaplegic homolog 3 isoform X2

      UniProtKB/TrEMBL
      A0A6J3QZ19
      Conserved Domains (2) summary
      cd10985
      Location:195 → 385
      MH2_SMAD_2_3; C-terminal Mad Homology 2 (MH2) domain in SMAD2 and SMAD3
      cl00055
      Location:38 → 103
      MH1; N-terminal Mad Homology 1 (MH1) domain

    3. XM_033851870.1 → XP_033707761.1  mothers against decapentaplegic homolog 3 isoform X3

      UniProtKB/TrEMBL
      A0A6J3QZC7
      Conserved Domains (2) summary
      cd10985
      Location:157 → 347
      MH2_SMAD_2_3; C-terminal Mad Homology 2 (MH2) domain in SMAD2 and SMAD3
      cl00055
      Location:3 → 65
      MH1; N-terminal Mad Homology 1 (MH1) domain

    RNA

    1. XR_004525216.1 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version

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