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    KMT2D lysine methyltransferase 2D [ Myotis lucifugus (little brown bat) ]

    Gene ID: 102434400, updated on 30-Mar-2024

    Summary

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    Gene symbol
    KMT2D
    Gene description
    lysine methyltransferase 2D
    See related
    Ensembl:ENSMLUG00000011179
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Myotis lucifugus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Chiroptera; Yangochiroptera; Vespertilionidae; Myotis
    Orthologs
    human mouse all
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    Genomic context

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    See KMT2D in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    56
    Annotation release Status Assembly Chr Location
    102 current Myoluc2.0 (GCF_000147115.1) Unplaced Scaffold NW_005871139.1 (2904321..2944414, complement)

    NW_005871139.1Genomic Context describing neighboring genes Neighboring gene dendrin Neighboring gene protein kinase AMP-activated non-catalytic subunit gamma 1 Neighboring gene RHEB like 1 Neighboring gene desert hedgehog signaling molecule

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_005871139 Unplaced Scaffold Reference Myoluc2.0

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables histone H3K4 methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables histone binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables transcription coactivator activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in positive regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of MLL3/4 complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    histone-lysine N-methyltransferase 2D

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Myotis lucifugus Annotation Release 102 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Myoluc2.0

    Genomic

    1. NW_005871139.1 Reference Myoluc2.0

      Range
      2904321..2944414 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006091577.3 → XP_006091639.1  histone-lysine N-methyltransferase 2D

      UniProtKB/TrEMBL
      G1PHU9
      Related
      ENSMLUP00000010258.2, ENSMLUT00000011258.2
      Conserved Domains (11) summary
      smart00398
      Location:1748 → 1799
      HMG; high mobility group
      smart00542
      Location:5006 → 5093
      FYRC; FY-rich domain, C-terminal region
      smart00317
      Location:5163 → 5285
      SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
      cd15509
      Location:228 → 273
      PHD1_KMT2C_like; PHD finger 1 found in Histone-lysine N-methyltransferase 2C (KMT2C) and 2D (KMT2D)
      cd15513
      Location:1156 → 1202
      PHD5_KMT2C_like; PHD finger 5 found in Histone-lysine N-methyltransferase 2C (KMT2C) and PHD finger 4 found in KMT2D
      cd15595
      Location:275 → 320
      PHD2_KMT2D; PHD finger 2 found in Histone-lysine N-methyltransferase 2D (KMT2D)
      cd15597
      Location:1105 → 1155
      PHD3_KMT2D; PHD finger 3 found in Histone-lysine N-methyltransferase 2D (KMT2D)
      cd15601
      Location:1233 → 1283
      PHD5_KMT2D; PHD finger 5 found in Histone-lysine N-methyltransferase 2D (KMT2D)
      cd15695
      Location:134 → 217
      ePHD1_KMT2D; Extended PHD finger 1 found in histone-lysine N-methyltransferase 2D (KMT2D)
      cd15698
      Location:4798 → 4904
      ePHD2_KMT2D; Extended PHD finger 2 found in histone-lysine N-methyltransferase 2D (KMT2D)
      pfam05964
      Location:4948 → 4998
      FYRN; F/Y-rich N-terminus
    Nucleotide Protein
    Heading Accession and Version

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