IFNG interferon gamma [Felis catus (domestic cat)] - Gene

Summary

Official Symbol: IFNG
Official Full Name: interferon gamma
Primary source: VGNC:VGNC:67703
See related: EnsemblRapid:ENSFCTG00005007021
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Felis catus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Felis
Orthologs: human mouse all
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Genomic context

Location:: chromosome: B4

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
105	current	F.catus_Fca126_mat1.0 (GCF_018350175.1)	B4	NC_058374.1 (93137484..93141840, complement)
104	previous assembly	Felis_catus_9.0 (GCF_000181335.3)	B4	NC_018729.3 (95329479..95334070, complement)

Chromosome B4 - NC_058374.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

demonstration that Foxp3 inhibits IL2, TNFalpha, and IFNgamma transcription by binding to their promoter regions in lentivirus-specific CD8(+) T cells; this is the first description of this process during the course of AIDS lentiviral infection
Title: T Regulatory Cell Induced Foxp3 Binds the IL2, IFNγ, and TNFα Promoters in Virus-Specific CD8(+) T Cells from Feline Immunodeficiency Virus Infected Cats.
Among single nucleotide polymorphisms, the feline IFN-gamma gene + 428 T allele was shown to be a feline infectious peritonitis (FIP)-resistant allele, and the heterozygous genotypes 01C/T and +408C/T were found to be FIP-susceptible factors.
Title: Identification and genotyping of feline infectious peritonitis-associated single nucleotide polymorphisms in the feline interferon-γ gene.

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables type II interferon receptor binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in immune response	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in extracellular region	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: interferon gamma

Names: IFN-gamma

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001009873.1 → NP_001009873.1 interferon gamma precursor

See identical proteins and their annotated locations for NP_001009873.1

Status: PROVISIONAL

Source sequence(s)

D30619

UniProtKB/Swiss-Prot

P46402

UniProtKB/TrEMBL

A9UKW5

Related

ENSFCTP00005012764.1, ENSFCTT00005019456.1

Conserved Domains (1) summary

pfam00714
Location:15 → 153

IFN-gamma; Interferon gamma

RefSeqs of Annotated Genomes: Felis catus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference F.catus_Fca126_mat1.0 Primary Assembly

Genomic

NC_058374.1 Reference F.catus_Fca126_mat1.0 Primary Assembly

Range

93137484..93141840 complement

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GenBank, FASTA, Sequence Viewer (Graphics)