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    CCL2 chemokine (C-C motif) ligand 2 [ Equus caballus (horse) ]

    Gene ID: 100034136, updated on 15-Aug-2024

    Summary

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    Gene symbol
    CCL2
    Gene description
    chemokine (C-C motif) ligand 2
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Equus caballus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
    Also known as
    MCP1; MCP-1; SCYA2
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    Genomic context

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    See CCL2 in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_08 current EquCab3.0 (GCF_002863925.1) 11 NC_009154.3 (38886881..38888824, complement)

    Chromosome 11 - NC_009154.3Genomic Context describing neighboring genes Neighboring gene C-C motif chemokine 7 Neighboring gene chemokine (C-C motif) ligand 11 Neighboring gene uncharacterized LOC111775694 Neighboring gene acid sensing ion channel subunit 2 Neighboring gene uncharacterized LOC111775693

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_009154.3 Chromosome 11 Reference EquCab3.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Cloning of equine chemokines eotaxin, monocyte chemoattractant protein (MCP)-1, MCP-2 and MCP-4, mRNA expression in tissues and induction by IL-4 in dermal fibroblasts. Benarafa C, et al. Vet Immunol Immunopathol, 2000 Oct 31. PMID 11044560
    2. Annotation of the Protein Coding Regions of the Equine Genome. Hestand MS, et al. PLoS One, 2015. PMID 26107351, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables chemokine activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in eosinophil chemotaxis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in immune response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    C-C motif chemokine 2
    Names
    monocyte chemoattractant protein 1
    monocyte chemotactic protein 1
    small-inducible cytokine A2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001081931.2 → NP_001075400.1  C-C motif chemokine 2 precursor

      See identical proteins and their annotated locations for NP_001075400.1

      Status: VALIDATED

      Source sequence(s)
      AJ251189, BM734875
      UniProtKB/Swiss-Prot
      Q9TTQ3
      UniProtKB/TrEMBL
      B1AB87, B3VMR2
      Conserved Domains (1) summary
      pfam00048
      Location:33 → 88
      IL8; Small cytokines (intecrine/chemokine), interleukin-8 like

    RefSeqs of Annotated Genomes: GCF_002863925.1-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference EquCab3.0 Primary Assembly

    Genomic

    1. NC_009154.3 Reference EquCab3.0 Primary Assembly

      Range
      38886881..38888824 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9TTQ3.1 GenPept UniProtKB/Swiss-Prot:Q9TTQ3

    Gene LinkOut

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