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    ssp sunspot [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 39375, updated on 4-Apr-2024

    Summary

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    Official Symbol
    sspprovided by FlyBase
    Official Full Name
    sunspotprovided by FlyBase
    Primary source
    FLYBASE:FBgn0036248
    Locus tag
    Dmel_CG17153
    See related
    AllianceGenome:FB:FBgn0036248
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG17153; Dmel\CG17153; Ssp
    Summary
    Enables beta-catenin binding activity. Involved in positive regulation of DNA endoreduplication; positive regulation of imaginal disc growth; and positive regulation of transcription, DNA-templated. Located in nuclear body and nuclear envelope. Is expressed in organism. Orthologous to human MSANTD1 (Myb/SANT DNA binding domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    Location:
    68F4-68F4; 3-38 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (12118257..12119789)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (12111357..12112889)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene versatile Neighboring gene uncharacterized protein Neighboring gene ypsilon schachtel

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The BED finger, a novel DNA-binding domain in chromatin-boundary-element-binding proteins and transposases. Aravind L. Trends Biochem Sci, 2000 Sep. PMID 10973053
    2. Sunspot, a link between Wingless signaling and endoreplication in Drosophila. Taniue K, et al. Development, 2010 May. PMID 20430750
    3. Drak/STK17A Drives Neoplastic Glial Proliferation through Modulation of MRLC Signaling. Chen AS, et al. Cancer Res, 2019 Mar 15. PMID 30530503, Free PMC Article
    4. A network model of the molecular organization of chromatin in Drosophila. van Bemmel JG, et al. Mol Cell, 2013 Feb 21. PMID 23438860
    5. Genomics of Recombination Rate Variation in Temperature-Evolved Drosophila melanogaster Populations. Winbush A, et al. Genome Biol Evol, 2021 Jan 7. PMID 33247719, Free PMC Article

    See all (29) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables beta-catenin binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in positive regulation of DNA endoreduplication IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in positive regulation of DNA-templated transcription IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in positive regulation of DNA-templated transcription IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in positive regulation of imaginal disc growth IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in nuclear body IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nuclear body IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nuclear envelope IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    sunspot
    Names
    CG17153-PA
    ssp-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      12118257..12119789
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_140289.3 → NP_648546.1  sunspot [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_648546.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VTT3
      Related
      FBpp0075724
      Conserved Domains (1) summary
      pfam13837
      Location:120 → 198
      Myb_DNA-bind_4; Myb/SANT-like DNA-binding domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VTT3 Q9VTT3

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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