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    mamld1 mastermind like domain containing 1 [ Xenopus tropicalis (tropical clawed frog) ]

    Gene ID: 100486942, updated on 6-Jul-2026
    Official Symbol
    mamld1provided by Xenbase
    Official Full Name
    mastermind like domain containing 1provided by Xenbase
    Primary source
    Xenbase:XB-GENE-6460427
    See related
    Ensembl:ENSXETG00000007743 AllianceGenome:Xenbase:XB-GENE-6460427
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Xenopus tropicalis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
    Also known as
    f18; hysp2; cxorf6
    Summary
    Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nuclear body. Human ortholog(s) of this gene implicated in hypospadias. Orthologous to human MAMLD1 (mastermind like domain containing 1). [provided by Alliance of Genome Resources, Jul 2025]
    Orthologs
    all
    Try the new Gene page
    Try the new Transcripts and proteins table
    See mamld1 in Genome Data Viewer
    Location:
    chromosome: 8
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    104 current UCB_Xtro_10.0 (GCF_000004195.4) 8 NC_030684.2 (57837822..57959594)
    103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 8 NC_030684.1 (36660171..36781069)

    Chromosome 8 - NC_030684.2Genomic Context describing neighboring genes Neighboring gene transmembrane protein 185A Neighboring gene iduronate 2-sulfatase Neighboring gene uncharacterized LOC116406926 Neighboring gene myotubularin 1 Neighboring gene myotubularin related protein 1

    Go to nucleotide: Graphics FASTA GenBank

    Related articles in PubMed

    1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Homology

    Gene Ontology Provided by Xenbase

    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Preferred Names
    mastermind-like domain-containing protein 1

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference UCB_Xtro_10.0 Primary Assembly

    Genomic

    1. NC_030684.2 Reference UCB_Xtro_10.0 Primary Assembly

      Range
      57837822..57959594
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_002934546.5 → XP_002934592.3  mastermind-like domain-containing protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A803JE16
      Related
      ENSXETP00000106144.1, ENSXETT00000120527.1
      Conserved Domains (1) summary
      PHA03247
      Location:178 → 439
      PHA03247; large tegument protein UL36; Provisional

    2. XM_012969490.3 → XP_012824944.2  mastermind-like domain-containing protein 1 isoform X2

      UniProtKB/TrEMBL
      F7D900
      Related
      ENSXETP00000016898.5, ENSXETT00000016898.5
      Conserved Domains (1) summary
      PHA03247
      Location:152 → 413
      PHA03247; large tegument protein UL36; Provisional
    Nucleotide Protein Strain
    Heading Accession and Version

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