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    Rpp30 RNaseP protein p30 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 44392, updated on 27-Mar-2024

    Summary

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    Official Symbol
    Rpp30provided by FlyBase
    Official Full Name
    RNaseP protein p30provided by FlyBase
    Primary source
    FLYBASE:FBgn0283652
    Locus tag
    Dmel_CG11606
    See related
    AllianceGenome:FB:FBgn0283652
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    #19/1; CG11606; coconut; Dmel\CG11606; l(2)k01901; RNase P; Rpp1
    Summary
    Predicted to enable ribonuclease P RNA binding activity. Involved in tRNA processing. Predicted to be part of nucleolar ribonuclease P complex and ribonuclease MRP complex. Orthologous to human RPP30 (ribonuclease P/MRP subunit p30). [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See Rpp30 in Genome Data Viewer
    Location:
    21B5-21B5; 2-0.5 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (251039..252373, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (251039..252373, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene kismet Neighboring gene mir-965 stem loop Neighboring gene long non-coding RNA:CR44218 Neighboring gene Dihydrouridine synthase 1 Neighboring gene long non-coding RNA:CR44219 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The effects of matrices of paired substitutions in mid-acceptor stem on Drosophila tRNA(His) structure and end-processing. Mohan A, et al. J Mol Biol, 2000 Nov 3. PMID 11054295
    2. Serotonin synchronises convergent extension of ectoderm with morphogenetic gastrulation movements in Drosophila. Colas JF, et al. Mech Dev, 1999 Sep. PMID 10495273
    3. Biogenesis of RNase P RNA from an intron requires co-assembly with cognate protein subunits. Palsule G, et al. Nucleic Acids Res, 2019 Sep 19. PMID 31287870, Free PMC Article
    4. tRNA processing defects induce replication stress and Chk2-dependent disruption of piRNA transcription. Molla-Herman A, et al. EMBO J, 2015 Dec 14. PMID 26471728, Free PMC Article
    5. Inventory and analysis of the protein subunits of the ribonucleases P and MRP provides further evidence of homology between the yeast and human enzymes. Rosenblad MA, et al. Nucleic Acids Res, 2006. PMID 16998185, Free PMC Article

    See all (34) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables ribonuclease P RNA binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in tRNA 5'-leader removal ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in tRNA processing IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in tRNA processing IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in tRNA processing IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of multimeric ribonuclease P complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    part_of nucleolar ribonuclease P complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of ribonuclease MRP complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    RNaseP protein p30
    Names
    CG11606-PA
    CG11606-PB
    Rpp30-PA
    Rpp30-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      251039..252373 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001272879.1 → NP_001259808.1  RNaseP protein p30, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001259808.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VPM0
      Conserved Domains (1) summary
      pfam01876
      Location:8 → 226
      RNase_P_p30; RNase P subunit p30

    2. NM_080010.4 → NP_524749.1  RNaseP protein p30, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_524749.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VPM0
      Related
      FBpp0077802
      Conserved Domains (1) summary
      pfam01876
      Location:8 → 226
      RNase_P_p30; RNase P subunit p30
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VPM0 Q9VPM0

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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