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    septin2.L septin 2 L homeolog [ Xenopus laevis (African clawed frog) ]

    Gene ID: 398203, updated on 2-May-2024

    Summary

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    Official Symbol
    septin2.L
    Official Full Name
    septin 2 L homeolog
    Primary source
    Xenbase:XB-GENE-865354
    Locus tag
    XELAEV_18027820mg
    See related
    EnsemblRapid:ENSXLAG00005015599
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Xenopus laevis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
    Also known as
    diff6; nedd5; sept2; septa; pnutl3; sept2-a; sept2-b; sept2.L; xlsepta; Septin-A; Septin-2A
    NEW
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    Genomic context

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    See septin2.L in Genome Data Viewer
    Location:
    chromosome: 5L
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 5L NC_054379.1 (135133330..135157335, complement)
    100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 5L NC_030732.1 (124057833..124081936, complement)

    Chromosome 5L - NC_054379.1Genomic Context describing neighboring genes Neighboring gene 5S ribosomal RNA Neighboring gene serine/threonine kinase 25 L homeolog Neighboring gene FERM, ARH/RhoGEF and pleckstrin domain protein 2 L homeolog Neighboring gene high density lipoprotein binding protein (vigilin) L homeolog Neighboring gene protein phosphatase 1 regulatory subunit 7 L homeolog

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. GTP binding induces filament assembly of a recombinant septin. Mendoza M, et al. Curr Biol, 2002 Oct 29. PMID 12419187
    2. Planar cell polarity acts through septins to control collective cell movement and ciliogenesis. Kim SK, et al. Science, 2010 Sep 10. PMID 20671153, Free PMC Article
    3. A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning. Kırlı K, et al. Elife, 2015 Dec 17. PMID 26673895, Free PMC Article
    4. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by Xenbase

    Function Evidence Code Pubs
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables molecular adaptor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within cell division IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within cilium assembly IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within cilium assembly ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    acts_upstream_of_or_within cytoskeleton-dependent cytokinesis IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within regulation of exocytosis IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within smoothened signaling pathway ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    colocalizes_with cell cortex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cell division site IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cell projection IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in ciliary membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in ciliary membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in cleavage furrow IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in microtubule cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in midbody IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of septin complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in septin ring IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in spindle IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in synaptic vesicle IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    septin-2A
    Names
    septin A

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001088592.1 → NP_001082061.1  septin-2A

      See identical proteins and their annotated locations for NP_001082061.1

      Status: PROVISIONAL

      Source sequence(s)
      AF212298
      UniProtKB/Swiss-Prot
      A0JMX2, Q63ZQ1, Q9DE33
      UniProtKB/TrEMBL
      A0A974CX07, B7ZR20
      Conserved Domains (1) summary
      pfam00735
      Location:34 → 305
      Septin

    RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Xenopus_laevis_v10.1 Primary Assembly

    Genomic

    1. NC_054379.1 Reference Xenopus_laevis_v10.1 Primary Assembly

      Range
      135133330..135157335 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_018261729.2 → XP_018117218.1  septin-2A isoform X2

      UniProtKB/Swiss-Prot
      Q63ZQ1
      UniProtKB/TrEMBL
      A0A8J0V9A4
      Related
      ENSXLAP00005045860.1, ENSXLAT00005046959.1

    2. XM_018261725.2 → XP_018117214.1  septin-2A isoform X1

      UniProtKB/Swiss-Prot
      A0JMX2, Q63ZQ1, Q9DE33
      UniProtKB/TrEMBL
      A0A974CX07, B7ZR20
      Related
      ENSXLAP00005045866.1, ENSXLAT00005046965.1
      Conserved Domains (1) summary
      pfam00735
      Location:34 → 305
      Septin

    3. XM_041562103.1 → XP_041418037.1  septin-2A isoform X3

      UniProtKB/Swiss-Prot
      Q63ZQ1
      UniProtKB/TrEMBL
      A0A8J1KMT5
      Conserved Domains (1) summary
      cd01850
      Location:31 → 304
      CDC_Septin; CDC/Septin GTPase family

    4. XM_018261726.2 → XP_018117215.1  septin-2A isoform X1

      UniProtKB/Swiss-Prot
      A0JMX2, Q63ZQ1, Q9DE33
      UniProtKB/TrEMBL
      A0A974CX07, B7ZR20
      Conserved Domains (1) summary
      pfam00735
      Location:34 → 305
      Septin

    5. XM_041562102.1 → XP_041418036.1  septin-2A isoform X1

      UniProtKB/Swiss-Prot
      A0JMX2, Q63ZQ1, Q9DE33
      UniProtKB/TrEMBL
      A0A974CX07, B7ZR20
      Conserved Domains (1) summary
      pfam00735
      Location:34 → 305
      Septin

    6. XM_018261728.2 → XP_018117217.1  septin-2A isoform X1

      UniProtKB/Swiss-Prot
      A0JMX2, Q63ZQ1, Q9DE33
      UniProtKB/TrEMBL
      A0A974CX07, B7ZR20
      Conserved Domains (1) summary
      pfam00735
      Location:34 → 305
      Septin

    7. XM_041562104.1 → XP_041418038.1  septin-2A isoform X3

      UniProtKB/Swiss-Prot
      Q63ZQ1
      UniProtKB/TrEMBL
      A0A8J1KMT5
      Related
      ENSXLAP00005045854.1, ENSXLAT00005046948.1
      Conserved Domains (1) summary
      cd01850
      Location:31 → 304
      CDC_Septin; CDC/Septin GTPase family
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9DE33.1 GenPept UniProtKB/Swiss-Prot:Q9DE33

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials