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    oatx organic anion transporter X [ Danio rerio (zebrafish) ]

    Gene ID: 555218, updated on 12-Sep-2024

    Summary

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    Official Symbol
    oatxprovided by ZNC
    Official Full Name
    organic anion transporter Xprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-070115-1
    See related
    AllianceGenome:ZFIN:ZDB-GENE-070115-1
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    oat1; oatl
    Summary
    Enables organic anion transmembrane transporter activity. Predicted to act upstream of or within transmembrane transport. Located in plasma membrane. Is expressed in several structures, including eye; heart; liver; skeletal muscle; and testis. [provided by Alliance of Genome Resources, Apr 2022]
    Annotation information
    Annotation category: partial on reference assembly
    Orthologs
    all
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    Genomic context

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    See oatx in Genome Data Viewer
    Location:
    chromosome: 21
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 21 NC_007132.7 (44085722..44104697, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 21 NC_007132.6 (44090558..44109655, complement)

    Chromosome 21 - NC_007132.7Genomic Context describing neighboring genes Neighboring gene arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 Neighboring gene IK cytokine Neighboring gene fibroblast growth factor 1b Neighboring gene gamma-aminobutyric acid type A receptor subunit alpha3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Environmental contaminants modulate transport activity of zebrafish organic anion transporters Oat1 and Oat3. Dragojević J, et al. Comp Biochem Physiol C Toxicol Pharmacol, 2020 May. PMID 32165351
    2. A natural complex product Yaocha reduces uric acid level in a live zebrafish model. Xiong XY, et al. J Pharmacol Toxicol Methods, 2020 Mar-Apr. PMID 32087362
    3. The flounder organic anion transporter fOat has sequence, function, and substrate specificity similarity to both mammalian Oat1 and Oat3. Aslamkhan AG, et al. Am J Physiol Regul Integr Comp Physiol, 2006 Dec. PMID 16857889, Free PMC Article
    4. Zebrafish (Danio rerio) Oat1 and Oat3 transporters and their interaction with physiological compounds. Dragojević J, et al. Comp Biochem Physiol B Biochem Mol Biol, 2019 Oct. PMID 31255699
    5. Phylogenetic, syntenic, and tissue expression analysis of slc22 genes in zebrafish (Danio rerio). Mihaljevic I, et al. BMC Genomics, 2016 Aug 12. PMID 27519738, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. physiological roles of Oat1 and Oat3 transporters in zebrafish
      Title: Zebrafish (Danio rerio) Oat1 and Oat3 transporters and their interaction with physiological compounds.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables organic anion transmembrane transporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within organic anion transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within transmembrane transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    solute carrier family 22 member 20; solute carrier family 22 member 6-A

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007132.7 Reference GRCz11 Primary Assembly

      Range
      44085722..44104697 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017353039.3 → XP_017208528.1  solute carrier family 22 member 6-A

      UniProtKB/TrEMBL
      A0A8M6Z3Y7
    Nucleotide Protein Strain
    Heading Accession and Version

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