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    FAM90A8 family with sequence similarity 90 member A8 [ Homo sapiens (human) ]

    Gene ID: 441324, updated on 10-Oct-2023

    Summary

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    Official Symbol
    FAM90A8provided by HGNC
    Official Full Name
    family with sequence similarity 90 member A8provided by HGNC
    Primary source
    HGNC:HGNC:32256
    See related
    Ensembl:ENSG00000285937 MIM:613045; AllianceGenome:HGNC:32256
    Gene type
    protein coding
    RefSeq status
    INFERRED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    FAM90A8P
    Summary
    FAM90A8 belongs to subfamily II of the primate-specific FAM90A gene family, which originated from multiple duplications and rearrangements (Bosch et al., 2007 [PubMed 17684299]). For background information on the FAM90A gene family, as well as information on the evolution of FAM90A genes, see FAM90A1 (MIM 613041).[supplied by OMIM, Oct 2009]
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    Genomic context

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    See FAM90A8 in Genome Data Viewer
    Location:
    8p23.1
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 8 NC_000008.11 (7738387..7741396)
    RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 8 NC_060932.1 (11884338..11887348)
    105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 8 NC_000008.10 (7595909..7598918)

    Chromosome 8 - NC_000008.11Genomic Context describing neighboring genes Neighboring gene translation initiation factor IF-2-like Neighboring gene family with sequence similarity 90 member A18 Neighboring gene family with sequence similarity 90 member A16 Neighboring gene family with sequence similarity 90 member A17 Neighboring gene family with sequence similarity 90 member A19

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Analysis of the multi-copy gene family FAM90A as a copy number variant in different ethnic backgrounds. Bosch N, et al. Gene, 2008 Sep 1. PMID 18602769
    2. Characterization and evolution of the novel gene family FAM90A in primates originated by multiple duplication and rearrangement events. Bosch N, et al. Hum Mol Genet, 2007 Nov 1. PMID 17684299

    GeneRIFs: Gene References Into Functions

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    General protein information

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    Preferred Names
    putative protein FAM90A8
    Names
    family with sequence similarity 90 member A8, pseudogene
    putative protein FAM90A8P

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001164450.1 → NP_001157922.1  putative protein FAM90A8

      Status: INFERRED

      Source sequence(s)
      AC084121
      UniProtKB/Swiss-Prot
      A6NJQ4, Q658T7
      Related
      ENSP00000498128.1, ENST00000647775.1
      Conserved Domains (1) summary
      pfam15288
      Location:41 → 80
      zf-CCHC_6; Zinc knuckle

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000008.11 Reference GRCh38.p14 Primary Assembly

      Range
      7738387..7741396
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060932.1 Alternate T2T-CHM13v2.0

      Range
      11884338..11887348
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NG_032083.2: Suppressed sequence

      Description
      NG_032083.2: This RefSeq was removed because it is now thought that this gene does encode a protein.
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A6NJQ4.1 GenPept UniProtKB/Swiss-Prot:A6NJQ4

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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