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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
Genomic
-
NG_009775.3 RefSeqGene
- Range
-
5063..244662
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
NM_000056.5 → NP_000047.1 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial isoform 1 precursor
See identical proteins and their annotated locations for NP_000047.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) lacks an alternate segment in the 3' UTR compared to transcript variant 1. Both variants 1 and 2 encode the same protein (isoform 1).
- Source sequence(s)
-
CA447889, U50708
- Consensus CDS
-
CCDS4994.1
- UniProtKB/Swiss-Prot
- P21953, Q5T2J3, Q9BQL0
- UniProtKB/TrEMBL
- A0A0K2GN21, A0A140VKB3
- Related
- ENSP00000348880.5, ENST00000356489.9
- Conserved Domains (1) summary
-
- PTZ00182
Location:66 → 390
- PTZ00182; 3-methyl-2-oxobutanate dehydrogenase; Provisional
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NM_001318975.1 → NP_001305904.1 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial isoform 2
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) uses an alternate splice site in the 5' region and initiates translation at a downstream start codon compared to variant 1. The encoded isoform (2) is shorter than isoform 1. Variants 3 and 13 both encode the same isoform (2).
- Source sequence(s)
-
AK304353, AL049696, CA447889, DC422376, M55575
- UniProtKB/TrEMBL
- B4E2N3, B7ZB80
- Conserved Domains (1) summary
-
- PTZ00182
Location:1 → 320
- PTZ00182; 3-methyl-2-oxobutanate dehydrogenase; Provisional
-
NM_001424035.1 → NP_001410964.1 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial isoform 3 precursor
Status: REVIEWED
- Description
- Transcript Variant: This variant (5) encodes the longest isoform (3).
- Source sequence(s)
-
AL049696, AL359715, AL391595
-
NM_001424036.1 → NP_001410965.1 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial isoform 1 precursor
Status: REVIEWED
- Source sequence(s)
-
AL049696, AL359715, AL391595
- UniProtKB/Swiss-Prot
- P21953, Q5T2J3, Q9BQL0
- UniProtKB/TrEMBL
-
A0A140VKB3
-
NM_001424037.1 → NP_001410966.1 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial isoform 4 precursor
Status: REVIEWED
- Source sequence(s)
-
AL049696, AL359715, AL391595
-
NM_001424038.1 → NP_001410967.1 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial isoform 5 precursor
Status: REVIEWED
- Source sequence(s)
-
AL049696, AL391595
-
NM_001424039.1 → NP_001410968.1 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial isoform 6 precursor
Status: REVIEWED
- Source sequence(s)
-
AL049696, AL391595
-
NM_001424040.1 → NP_001410969.1 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial isoform 7 precursor
Status: REVIEWED
- Source sequence(s)
-
AL049696, AL391595
-
NM_001424041.1 → NP_001410970.1 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial isoform 8 precursor
Status: REVIEWED
- Source sequence(s)
-
AL049696, AL391595
-
NM_001424042.1 → NP_001410971.1 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial isoform 9 precursor
Status: REVIEWED
- Source sequence(s)
-
AL049696, AL391595
-
NM_001424043.1 → NP_001410972.1 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial isoform 2
Status: REVIEWED
- Source sequence(s)
-
AL049696, AL391595
- UniProtKB/TrEMBL
-
B7ZB80
-
NM_001424044.1 → NP_001410973.1 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial isoform 10 precursor
Status: REVIEWED
- Source sequence(s)
-
AL391595
-
NM_001424045.1 → NP_001410974.1 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial isoform 11 precursor
Status: REVIEWED
- Source sequence(s)
-
AL391595
- Related
- ENSP00000358775.4, ENST00000369760.8
-
NM_183050.4 → NP_898871.1 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial isoform 1 precursor
See identical proteins and their annotated locations for NP_898871.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) encodes isoform 1. Both variants 1 and 2 encode the same protein (isoform 1).
- Source sequence(s)
-
AL049696, CA447889, DC372349, M55575
- Consensus CDS
-
CCDS4994.1
- UniProtKB/Swiss-Prot
- P21953, Q5T2J3, Q9BQL0
- UniProtKB/TrEMBL
- A0A0K2GN21, A0A140VKB3
- Related
- ENSP00000318351.5, ENST00000320393.9
- Conserved Domains (1) summary
-
- PTZ00182
Location:66 → 390
- PTZ00182; 3-methyl-2-oxobutanate dehydrogenase; Provisional
RNA
-
NR_134945.2 RNA Sequence
Status: REVIEWED
- Description
- Transcript Variant: This variant (4) contains an alternate internal exon compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
- Source sequence(s)
-
AL049696, BC034481, CA447889
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NR_187561.1 RNA Sequence
Status: REVIEWED
- Source sequence(s)
-
AL049696, AL391595
-
NR_187562.1 RNA Sequence
Status: REVIEWED
- Source sequence(s)
-
AL049696, AL391595
-
NR_187563.1 RNA Sequence
Status: REVIEWED
- Source sequence(s)
-
AL049696, AL391595
-
NR_187564.1 RNA Sequence
Status: REVIEWED
- Source sequence(s)
-
AL049696, AL391595
-
NR_187565.1 RNA Sequence
Status: REVIEWED
- Source sequence(s)
-
AL049696, AL391595
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000006.12 Reference GRCh38.p14 Primary Assembly
- Range
-
80106610..80466676
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_047419211.1 → XP_047275167.1 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial isoform X9
-
XM_047419212.1 → XP_047275168.1 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial isoform X9
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XM_047419210.1 → XP_047275166.1 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial isoform X8
-
XM_047419207.1 → XP_047275163.1 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial isoform X1
- UniProtKB/Swiss-Prot
- P21953, Q5T2J3, Q9BQL0
- UniProtKB/TrEMBL
-
A0A140VKB3
-
XM_005248756.6 → XP_005248813.1 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial isoform X3
- UniProtKB/TrEMBL
-
A0A0K2GN21
- Conserved Domains (2) summary
-
- cd07036
Location:75 → 241
- TPP_PYR_E1-PDHc-beta_like; Pyrimidine (PYR) binding domain of the beta subunits of the E1 components of human pyruvate dehydrogenase complex (E1- PDHc) and related proteins
- pfam02780
Location:262 → 346
- Transketolase_C; Transketolase, C-terminal domain
-
XM_047419213.1 → XP_047275169.1 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial isoform X5
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XM_047419214.1 → XP_047275170.1 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial isoform X7
- UniProtKB/TrEMBL
-
B7ZB80
RNA
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XR_001743546.3 RNA Sequence
Alternate T2T-CHM13v2.0
Genomic
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NC_060930.1 Alternate T2T-CHM13v2.0
- Range
-
81315017..81677450
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_054356140.1 → XP_054212115.1 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial isoform X1
- UniProtKB/Swiss-Prot
- P21953, Q5T2J3, Q9BQL0
- UniProtKB/TrEMBL
-
A0A140VKB3
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XM_054356143.1 → XP_054212118.1 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial isoform X3
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XM_054356145.1 → XP_054212120.1 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial isoform X5
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XM_054356147.1 → XP_054212122.1 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial isoform X7
- UniProtKB/TrEMBL
-
B7ZB80
RNA
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XR_008487369.1 RNA Sequence
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XR_008487371.1 RNA Sequence
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XR_008487372.1 RNA Sequence
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XR_008487373.1 RNA Sequence
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XR_008487370.1 RNA Sequence