U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    TNFSF15 TNF superfamily member 15 [ Homo sapiens (human) ]

    Gene ID: 9966, updated on 17-Jun-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    TL1A is an epithelial alarmin that cooperates with IL-33 for initiation of allergic airway inflammation.

    TL1A is an epithelial alarmin that cooperates with IL-33 for initiation of allergic airway inflammation.
    Schmitt P, Duval A, Camus M, Lefrançais E, Roga S, Dedieu C, Ortega N, Bellard E, Mirey E, Mouton-Barbosa E, Burlet-Schiltz O, Gonzalez-de-Peredo A, Cayrol C, Girard JP., Free PMC Article

    04/24/2024
    The Relation of VEGFA, VEGFR2, VEGI, and HIF1A Genetic Variants and Their Serum Protein Levels with Breast Cancer in Egyptian Patients.

    The Relation of VEGFA, VEGFR2, VEGI, and HIF1A Genetic Variants and Their Serum Protein Levels with Breast Cancer in Egyptian Patients.
    Abdelgalil AA, Monir R, Elmetwally M, Ghattas MH, Bazeed FB, Mesbah NM, Abo-Elmatty DM, Mehanna ET.

    03/4/2024
    Genetic architecture of the inflammatory bowel diseases across East Asian and European ancestries.

    Genetic architecture of the inflammatory bowel diseases across East Asian and European ancestries.
    Liu Z, Liu R, Gao H, Jung S, Gao X, Sun R, Liu X, Kim Y, Lee HS, Kawai Y, Nagasaki M, Umeno J, Tokunaga K, Kinouchi Y, Masamune A, Shi W, Shen C, Guo Z, Yuan K, FinnGen, International Inflammatory Bowel Disease Genetics Consortium, Chinese Inflammatory Bowel Disease Genetics Consortium, Zhu S, Li D, Liu J, Ge T, Cho J, Daly MJ, McGovern DPB, Ye BD, Song K, Kakuta Y, Li M, Huang H., Free PMC Article

    05/24/2023
    Increased Serum Levels of Tumor Necrosis Factor-like Ligand 1A in Atopic Dermatitis.

    Increased Serum Levels of Tumor Necrosis Factor-like Ligand 1A in Atopic Dermatitis.
    Hisamoto T, Suga H, Yoshizaki-Ogawa A, Sato S, Yoshizaki A., Free PMC Article

    02/16/2023
    Immune Checkpoint Inhibitor (ICI) Genes and Aging in Clear Cell Renal Cell Carcinoma (ccRCC): Clinical and Genomic Study.

    Immune Checkpoint Inhibitor (ICI) Genes and Aging in Clear Cell Renal Cell Carcinoma (ccRCC): Clinical and Genomic Study.
    Al-Danakh A, Safi M, Alradhi M, Chen Q, Baldi S, Zhu X, Yang D., Free PMC Article

    12/3/2022
    Role of TNFSF15 variants in oral cancer development and clinicopathologic characteristics.

    Role of TNFSF15 variants in oral cancer development and clinicopathologic characteristics.
    Lu HJ, Chuang CY, Su CW, Chen MK, Yang WE, Yeh CM, Tang CH, Lin CW, Yang SF., Free PMC Article

    11/12/2022
    Genome-wide association study identifies TNFSF15 associated with childhood asthma.

    Genome-wide association study identifies TNFSF15 associated with childhood asthma.
    Kim KW, Kim DY, Yoon D, Kim KK, Jang H, Schoettler N, Kim EG, Kim MN, Hong JY, Lee JK, Kim S, Ober C, Gee HY, Sohn MH., Free PMC Article

    04/16/2022
    Nonylphenol regulates TL1A through the AhR/HDAC2/HNF4alpha pathway in endothelial cells to promote the angiogenesis of colorectal cancer.

    Nonylphenol regulates TL1A through the AhR/HDAC2/HNF4α pathway in endothelial cells to promote the angiogenesis of colorectal cancer.
    Zhang T, Ning WW, Zhang J, Xu FJ, Wang XQ, Li ZB, Xie M.

    02/26/2022
    The relationship between TNF-like protein 1A and coronary artery aneurysms in children with Kawasaki disease.

    The relationship between TNF-like protein 1A and coronary artery aneurysms in children with Kawasaki disease.
    Zhang J, Weng H, Pei Q, Yang P, Fan W, Liu R, Yi Q.

    02/26/2022
    Effect and Mechanism of TL1A Expression on Epithelial-Mesenchymal Transition during Chronic Colitis-Related Intestinal Fibrosis.

    Effect and Mechanism of TL1A Expression on Epithelial-Mesenchymal Transition during Chronic Colitis-Related Intestinal Fibrosis.
    Wenxiu J, Mingyue Y, Fei H, Yuxin L, Mengyao W, Chenyang L, Jia S, Hong Z, Shih DQ, Targan SR, Xiaolan Z., Free PMC Article

    01/8/2022
    TNFSF15 Promotes Antimicrobial Pathways in Human Macrophages and These Are Modulated by TNFSF15 Disease-Risk Variants.

    TNFSF15 Promotes Antimicrobial Pathways in Human Macrophages and These Are Modulated by TNFSF15 Disease-Risk Variants.
    Sun R, Hedl M, Abraham C., Free PMC Article

    12/25/2021
    Common risk variants in NPHS1 and TNFSF15 are associated with childhood steroid-sensitive nephrotic syndrome.

    Common risk variants in NPHS1 and TNFSF15 are associated with childhood steroid-sensitive nephrotic syndrome.
    Jia X, Yamamura T, Gbadegesin R, McNulty MT, Song K, Nagano C, Hitomi Y, Lee D, Aiba Y, Khor SS, Ueno K, Kawai Y, Nagasaki M, Noiri E, Horinouchi T, Kaito H, Hamada R, Okamoto T, Kamei K, Kaku Y, Fujimaru R, Tanaka R, Shima Y, Research Consortium on Genetics of Childhood Idiopathic Nephrotic Syndrome in Japan, Baek J, Kang HG, Ha IS, Han KH, Yang EM, Korean Consortium of Hereditary Renal Diseases in Children, Abeyagunawardena A, Lane B, Chryst-Stangl M, Esezobor C, Solarin A, Midwest Pediatric Nephrology Consortium (Genetics of Nephrotic Syndrome Study Group), Dossier C, Deschênes G, NEPHROVIR, Vivarelli M, Debiec H, Ishikura K, Matsuo M, Nozu K, Ronco P, Cheong HI, Sampson MG, Tokunaga K, Iijima K., Free PMC Article

    08/7/2021
    TNFSF15 Polymorphisms are Associated with Graves' Disease and Graves' Ophthalmopathy in a Han Chinese Population.

    TNFSF15 Polymorphisms are Associated with Graves' Disease and Graves' Ophthalmopathy in a Han Chinese Population.
    Zhang M, Liu S, Xu J, Lv S, Fan Y, Zhang Y, Zhang Y, Wu Y, Su Y, Yu H, Song S, He J, Li H.

    08/7/2021
    Polymorphism rs6478109 in the TNFSF15 gene contributes to the susceptibility to Crohn's disease but not ulcerative colitis: a meta-analysis.

    Polymorphism rs6478109 in the TNFSF15 gene contributes to the susceptibility to Crohn's disease but not ulcerative colitis: a meta-analysis.
    Zhou Y, Zhu Y, Jiang H, Chen Z, Lu B, Li J, Shen X., Free PMC Article

    07/24/2021
    Intraocular tumour necrosis factor ligand related molecule 1 A links disease progression of proliferative diabetic retinopathy after primary vitrectomy.

    Intraocular tumour necrosis factor ligand related molecule 1 A links disease progression of proliferative diabetic retinopathy after primary vitrectomy.
    Wang T, Li J, Xie R, Wang J, Zhang W, Jiang F, Du M, Wang X, Huang B, Brant R, Zhang C, Yan H.

    07/17/2021
    Circulating TNF-like protein 1A (TL1A) is elevated early in rheumatoid arthritis and depends on TNF.

    Circulating TNF-like protein 1A (TL1A) is elevated early in rheumatoid arthritis and depends on TNF.
    Song YJ, Choi IA, Meylan F, Demoruelle MK, Farley T, Richard AC, Hawley E, Botson J, Hong YJ, Lee EY, Mian SR, Hamilton BC, Thiele GM, Mikuls TR, Gara N, Ward CD, Lamberth S, Deane KD, Heller T, Ward MM, Lee DM, Migone TS, Stohl W, O'Dell JR, Norris JM, Holers VM, Gregersen P, Song YW, Siegel RM., Free PMC Article

    06/19/2021
    TL1A/TNFR2-mediated mitochondrial dysfunction of fibroblast-like synoviocytes increases inflammatory response in patients with rheumatoid arthritis via reactive oxygen species generation.

    TL1A/TNFR2-mediated mitochondrial dysfunction of fibroblast-like synoviocytes increases inflammatory response in patients with rheumatoid arthritis via reactive oxygen species generation.
    Al-Azab M, Qaed E, Ouyang X, Elkhider A, Walana W, Li H, Li W, Tang Y, Adlat S, Wei J, Wang B, Li X.

    05/15/2021
    TNFSF15 (rs3810936) in Behcet's disease.

    TNFSF15 (rs3810936) in Behçet's disease.
    Sediq AM, Esawy MM, Hassanin HM, Abdul-Maksoud RS, Salama MA, Abdelwahab SM.

    05/15/2021
    TNFSF15 facilitates human umbilical cord blood haematopoietic stem cell expansion by activating Notch signal pathway.

    TNFSF15 facilitates human umbilical cord blood haematopoietic stem cell expansion by activating Notch signal pathway.
    Ding Y, Gao S, Shen J, Bai T, Yang M, Xu S, Gao Y, Zhang Z, Li L., Free PMC Article

    05/8/2021
    TL1A-DR3 Plasma Levels Are Predictive of HIV-1 Disease Control, and DR3 Costimulation Boosts HIV-1-Specific T Cell Responses.

    TL1A-DR3 Plasma Levels Are Predictive of HIV-1 Disease Control, and DR3 Costimulation Boosts HIV-1-Specific T Cell Responses.
    Oriol-Tordera B, Olvera A, Duran-Castells C, Llano A, Mothe B, Massanella M, Dalmau J, Ganoza C, Sanchez J, Calle ML, Clotet B, Martinez-Picado J, Negredo E, Blanco J, Hartigan-O'Connor D, Brander C, Ruiz-Riol M., Free PMC Article

    04/17/2021
    A TRAIL-TL1A Paracrine Network Involving Adipocytes, Macrophages, and Lymphocytes Induces Adipose Tissue Dysfunction Downstream of E2F1 in Human Obesity.

    A TRAIL-TL1A Paracrine Network Involving Adipocytes, Macrophages, and Lymphocytes Induces Adipose Tissue Dysfunction Downstream of E2F1 in Human Obesity.
    Maixner N, Pecht T, Haim Y, Chalifa-Caspi V, Goldstein N, Tarnovscki T, Liberty IF, Kirshtein B, Golan R, Berner O, Monsonego A, Bashan N, Blüher M, Rudich A., Free PMC Article

    02/2/2021
    Pathologic up-regulation of TNFSF15-TNFRSF25 axis sustains endothelial dysfunction in unprovoked venous thromboembolism.

    Pathologic up-regulation of TNFSF15-TNFRSF25 axis sustains endothelial dysfunction in unprovoked venous thromboembolism.
    Della Bella S, Calcaterra F, Bacci M, Carenza C, Pandolfo C, Ferrazzi P, Uva P, Pagani M, Lodigiani C, Mavilio D.

    10/24/2020
    TNFSF/TNFRSF cytokine gene expression in sickle cell anemia: Up-regulated TNF-like cytokine 1A (TL1A) and its decoy receptor (DcR3) in peripheral blood mononuclear cells and plasma.

    TNFSF/TNFRSF cytokine gene expression in sickle cell anemia: Up-regulated TNF-like cytokine 1A (TL1A) and its decoy receptor (DcR3) in peripheral blood mononuclear cells and plasma.
    Safaya S, Alfarhan M, Sulaiman A, Alsulaiman A, Al-Ali A.

    09/12/2020
    These findings indicate that gene polymorphisms (rs3810936, rs7848647) of TL1A might correlate with lupus.

    Association between TL1A gene polymorphisms and systemic lupus erythematosus in a Chinese Han population.
    Xu WD, Fu L, Liu XY, Wang JM, Yuan ZC, Su LC, Huang AF.

    06/27/2020
    The identifies a new inflammatory mechanism in Mucosal-associated invariant T cells linking the DR3/TL1A axis with amplification of TCR-dependent and -independent effector functions, particularly inducing excessive innate TNF-alpha production.

    The TL1A-DR3 Axis Selectively Drives Effector Functions in Human MAIT Cells.
    Sattler A, Thiel LG, Ruhm AH, Souidi N, Seifert M, Herberth G, Kotsch K.

    05/30/2020
    firstprevious page of 6 nextlast