| MAGI2 ameliorates podocyte apoptosis of diabetic kidney disease through communication with TGF-beta-Smad3/nephrin pathway. | MAGI2 ameliorates podocyte apoptosis of diabetic kidney disease through communication with TGF-β-Smad3/nephrin pathway.
Wang T, Li C, Wang X, Liu F. | 11/15/2023 |
| The TLR4/NF-kappaB/MAGI-2 signaling pathway mediates postoperative delirium. | The TLR4/NF-κB/MAGI-2 signaling pathway mediates postoperative delirium.
Zhang W, Wang R, Yuan J, Li B, Zhang L, Wang Y, Zhu R, Zhang J, Huyan T., Free PMC Article | 04/16/2022 |
| Comparative study of immunohistochemical expression of ERG and MAGI2 in prostatic carcinoma. | Comparative study of immunohistochemical expression of ERG and MAGI2 in prostatic carcinoma.
Dawoud MM, Aiad HA, Bahbah AMNH, Shaban MI. | 11/27/2021 |
| HIST1H2BB and MAGI2 Methylation and Somatic Mutations as Precision Medicine Biomarkers for Diagnosis and Prognosis of High-grade Serous Ovarian Cancer. | HIST1H2BB and MAGI2 Methylation and Somatic Mutations as Precision Medicine Biomarkers for Diagnosis and Prognosis of High-grade Serous Ovarian Cancer.
Valle BL, Rodriguez-Torres S, Kuhn E, Díaz-Montes T, Parrilla-Castellar E, Lawson FP, Folawiyo O, Ili-Gangas C, Brebi-Mieville P, Eshleman JR, Herman J, Shih IM, Sidransky D, Guerrero-Preston R., Free PMC Article | 11/6/2021 |
| Polymorphism in the MAGI2 Gene Modifies the Effect of Amyloid beta on Neurodegeneration. | Polymorphism in the MAGI2 Gene Modifies the Effect of Amyloid β on Neurodegeneration.
Kim HR, Lee T, Choi JK, Jeong Y, Alzheimer’s Disease Neuroimaging Initiative. | 10/23/2021 |
| GLIDR promotes the progression of glioma by regulating the miR-4677-3p/MAGI2 axis. | GLIDR promotes the progression of glioma by regulating the miR-4677-3p/MAGI2 axis.
Yu Q, Li X, Feng T. | 10/23/2021 |
| Genetic variants of SDCCAG8 and MAGI2 in mitosis-related pathway genes are independent predictors of cutaneous melanoma-specific survival. | Genetic variants of SDCCAG8 and MAGI2 in mitosis-related pathway genes are independent predictors of cutaneous melanoma-specific survival.
He Y, Liu H, Luo S, Amos CI, Lee JE, Li X, Nan H, Wei Q., Free PMC Article | 10/16/2021 |
| MAGI-2 downregulation: a potential predictor of tumor progression and early recurrence in Han Chinese patients with prostate cancer. | MAGI-2 downregulation: a potential predictor of tumor progression and early recurrence in Han Chinese patients with prostate cancer.
Cao Z, Ji J, Wang FB, Kong C, Xu H, Xu YL, Chen X, Yu YW, Sun YH., Free PMC Article | 09/25/2021 |
| MAGI2-AS3 inhibits breast cancer by downregulating DNA methylation of MAGI2. | MAGI2-AS3 inhibits breast cancer by downregulating DNA methylation of MAGI2.
Xu X, Yuan X, Ni J, Guo J, Gao Y, Yin W, Li F, Wei L, Zhang J. | 09/11/2021 |
| Novel insights for lncRNA MAGI2-AS3 in solid tumors. | Novel insights for lncRNA MAGI2-AS3 in solid tumors.
Xue C, Li G, Lu J, Luo J, Jia J. | 07/24/2021 |
| LncRNA MAGI2-AS3 is downregulated in non-small cell lung cancer and may be a sponge of miR-25. | LncRNA MAGI2-AS3 is downregulated in non-small cell lung cancer and may be a sponge of miR-25.
Sui Y, Chi W, Feng L, Jiang J., Free PMC Article | 01/23/2021 |
| Disruption of MAGI2-RapGEF2-Rap1 signaling contributes to podocyte dysfunction in congenital nephrotic syndrome caused by mutations in MAGI2. | Disruption of MAGI2-RapGEF2-Rap1 signaling contributes to podocyte dysfunction in congenital nephrotic syndrome caused by mutations in MAGI2.
Zhu B, Cao A, Li J, Young J, Wong J, Ashraf S, Bierzynska A, Menon MC, Hou S, Sawyers C, Campbell KN, Saleem MA, He JC, Hildebrandt F, D'Agati VD, Peng W, Kaufman L., Free PMC Article | 10/24/2020 |
| MAGI2 gene polymorphism rs2160322 is associated with Graves' disease and not with Hashimoto's thyroiditis. | The MAGI2 gene polymorphism rs2160322 is associated with Graves' disease but not with Hashimoto's thyroiditis.
Jia X, Zhai T, Wang B, Zhang J, Zhang F. | 12/14/2019 |
| MAGI2 expression is reduced during prostate cancer progression and that retention of MAGI2 signal reduces odds of biochemical recurrence. Decreased MAGI2 expression may help predict prostate cancer aggressiveness. | MAGI2 is an independent predictor of biochemical recurrence in prostate cancer.
David SN, Arnold Egloff SA, Goyal R, Clark PE, Phillips S, Gellert LL, Hameed O, Giannico GA. | 03/9/2019 |
| MAGI2-AS3 plays an important role as a tumour suppressor by targeting Fas and FasL signalling. | Long non-coding RNA (lncRNA) MAGI2-AS3 inhibits breast cancer cell growth by targeting the Fas/FasL signalling pathway.
Yang Y, Yang H, Xu M, Zhang H, Sun M, Mu P, Dong T, Du S, Liu K. | 08/11/2018 |
| MAGI-2 immunoreactivity is elevated in prostate cancer and high-grade prostatic intraepithelial neoplasia compared with normal tissue, suggesting that MAGI-2 may contribute to prostate carcinogenesis. | MAGI-2 in prostate cancer: an immunohistochemical study.
Goldstein J, Borowsky AD, Goyal R, Roland JT, Arnold SA, Gellert LL, Clark PE, Hameed O, Giannico GA. | 08/19/2017 |
| Immunohistochemistry in kidney sections from these patients revealed that mutations resulted in lack of or diminished podocyte MAGI2 expression. Our data support the finding that mutations in the MAGI2 gene are causal for congenital steroid-resistant nephrotic syndrome | MAGI2 Mutations Cause Congenital Nephrotic Syndrome.
Bierzynska A, Soderquest K, Dean P, Colby E, Rollason R, Jones C, Inward CD, McCarthy HJ, Simpson MA, Lord GM, Williams M, Welsh GI, Koziell AB, Saleem MA, NephroS, UK study of Nephrotic Syndrome., Free PMC Article | 06/3/2017 |
| MAGI-2 could represent a useful adjunct for diagnosis of prostatic adenocarcinoma | MAGI-2 Is a Sensitive and Specific Marker of Prostatic Adenocarcinoma: A Comparison With AMACR.
Goldstein J, Goyal R, Roland JT, Gellert LL, Clark PE, Hameed O, Giannico GA. | 03/11/2017 |
| The expression of MAGI2 mRNA was significantly down-regulated in PC3, LNCaP and DU-145 PCa cell lines. | Expression profile of MAGI2 gene as a novel biomarker in combination with major deregulated genes in prostate cancer.
Mahdian R, Nodouzi V, Asgari M, Rezaie M, Alizadeh J, Yousefi B, Shahrokh H, Abolhasani M, Nowroozi M. | 12/12/2015 |
| MAGI2, SERPINE2, and NT5C3B expression levels are associated with airway wall thickening and additionally with bronchial inflammation, emphysema, and lung function, respectively, all features of chronic obstructive pulmonary disease. | Novel genes for airway wall thickness identified with combined genome-wide association and expression analyses.
Dijkstra AE, Postma DS, van Ginneken B, Wielpütz MO, Schmidt M, Becker N, Owsijewitsch M, Kauczor HU, de Koning HJ, Lammers JW, Oudkerk M, Brandsma CA, Bossé Y, Nickle DC, Sin DD, Hiemstra PS, Wijmenga C, Smolonska J, Zanen P, Vonk JM, van den Berge M, Boezen HM, Groen HJ. | 05/9/2015 |
| Data show that the miR-134/487b/655 cluster regulates TGF-beta1-induced epithelial-mesenchymal transition and affected the resistance to gefitinib by directly targeting membrane-associated guanylate kinase, WW, and PDZ domain-containing protein 2 (MAGI2). | MiR-134/487b/655 cluster regulates TGF-β-induced epithelial-mesenchymal transition and drug resistance to gefitinib by targeting MAGI2 in lung adenocarcinoma cells.
Kitamura K, Seike M, Okano T, Matsuda K, Miyanaga A, Mizutani H, Noro R, Minegishi Y, Kubota K, Gemma A. | 02/21/2015 |
| In Usher syndrome 1G, mutations in SANS eliminate Magi2 binding and thereby deregulate endocytosis, lead to defective ciliary transport modules and ultimately disrupt photoreceptor cell function inducing retinal degeneration. | Phosphorylation of the Usher syndrome 1G protein SANS controls Magi2-mediated endocytosis.
Bauß K, Knapp B, Jores P, Roepman R, Kremer H, Wijk EV, Märker T, Wolfrum U. | 02/21/2015 |
| MAGI2 enhances the sensitivity of BEL-7404 human hepatocellular carcinoma cells to staurosporine-induced apoptosis by increasing PTEN stability. | MAGI2 enhances the sensitivity of BEL-7404 human hepatocellular carcinoma cells to staurosporine-induced apoptosis by increasing PTEN stability.
Li X, Li Z, Li N, Qi J, Fan K, Yin P, Zhao C, Liu Y, Yao W, Cai X, Wang L, Zha X. | 06/14/2014 |
| Common variants in MAGI2 gene are associated with increased risk for cognitive impairment in schizophrenic patients. | Common variants in MAGI2 gene are associated with increased risk for cognitive impairment in schizophrenic patients.
Koide T, Banno M, Aleksic B, Yamashita S, Kikuchi T, Kohmura K, Adachi Y, Kawano N, Kushima I, Nakamura Y, Okada T, Ikeda M, Ohi K, Yasuda Y, Hashimoto R, Inada T, Ujike H, Iidaka T, Suzuki M, Takeda M, Iwata N, Ozaki N., Free PMC Article | 10/13/2012 |
| Results presented herein provide further evidence for a role of MAGI2 in bipolar affective disorder and schizophrenia etiology. | MAGI1 copy number variation in bipolar affective disorder and schizophrenia.
Karlsson R, Graae L, Lekman M, Wang D, Favis R, Axelsson T, Galter D, Belin AC, Paddock S. | 09/1/2012 |