| SPOCK: Master regulator of malignant tumors (Review). | SPOCK: Master regulator of malignant tumors (Review).
Xiao M, Xue J, Jin E., Free PMC Article | 10/22/2024 |
| The novel prognostic marker SPOCK2 regulates tumour progression in melanoma. | The novel prognostic marker SPOCK2 regulates tumour progression in melanoma.
Kang JY, Cho H, Gil M, Lee H, Park S, Kim KE. | 06/28/2024 |
| SPOCK2 gene expression is downregulated in pancreatic ductal adenocarcinoma cells and correlates with prognosis of patients with pancreatic cancer. | SPOCK2 gene expression is downregulated in pancreatic ductal adenocarcinoma cells and correlates with prognosis of patients with pancreatic cancer.
Aghamaliyev U, Su K, Weniger M, Koch D, D'Haese JG, Werner J, Bazhin AV., Free PMC Article | 08/1/2023 |
| Integrated bulk and single-cell RNA-sequencing reveals SPOCK2 as a novel biomarker gene in the development of congenital pulmonary airway malformation. | Integrated bulk and single-cell RNA-sequencing reveals SPOCK2 as a novel biomarker gene in the development of congenital pulmonary airway malformation.
Tan Z, Li F, Chen Q, Chen H, Xue Z, Zhang J, Gao Y, Liang L, Huang T, Zhang S, Li J, Shu Q, Yu L., Free PMC Article | 05/17/2023 |
| SPOCK2 and SPRED1 function downstream of EZH2 to impede the malignant progression of lung adenocarcinoma in vitro and in vivo. | SPOCK2 and SPRED1 function downstream of EZH2 to impede the malignant progression of lung adenocarcinoma in vitro and in vivo.
Liu Y, Fan X, Jiang C, Xu S., Free PMC Article | 03/16/2023 |
| Testican-2 Is Associated with Reduced Risk of Incident ESKD. | Testican-2 Is Associated with Reduced Risk of Incident ESKD.
Wen D, Zhou L, Zheng Z, Surapaneni A, Ballantyne CM, Hoogeveen RC, Shlipak MG, Waikar SS, Vasan RS, Kimmel PL, Dubin RF, Deo R, Feldman HI, Ganz P, Coresh J, Grams ME, Rhee EP, CKD Biomarkers Consortium., Free PMC Article | 02/4/2023 |
| Downregulation of SPOCK2 promotes the proliferation, adhesion, and invasion of endometrial epithelial cells. | Downregulation of SPOCK2 promotes the proliferation, adhesion, and invasion of endometrial epithelial cells.
Ren F, Wang Y, Chen P, Guo C. | 11/22/2021 |
| SPOCK2 Affects the Biological Behavior of Endometrial Cancer Cells by Regulation of MT1-MMP and MMP2. | SPOCK2 Affects the Biological Behavior of Endometrial Cancer Cells by Regulation of MT1-MMP and MMP2.
Ren F, Wang D, Wang Y, Chen P, Guo C. | 12/19/2020 |
| Circulating testican-2 is a podocyte-derived marker of kidney health. | Circulating testican-2 is a podocyte-derived marker of kidney health.
Ngo D, Wen D, Gao Y, Keyes MJ, Drury ER, Katz DH, Benson MD, Sinha S, Shen D, Farrell LA, Peterson BD, Friedman DJ, Elmariah S, Young BA, Smith JG, Yang Q, Vasan RS, Larson MG, Correa A, Humphreys BD, Wang TJ, Pollak MR, Wilson JG, Gerszten RE, Rhee EP., Free PMC Article | 11/28/2020 |
| Dysregulation of pseudogene/lncRNA-hsa-miR-363-3p-SPOCK2 pathway fuels stage progression of ovarian cancer. | Dysregulation of pseudogene/lncRNA-hsa-miR-363-3p-SPOCK2 pathway fuels stage progression of ovarian cancer.
Lou W, Ding B, Zhong G, Du C, Fan W, Fu P., Free PMC Article | 10/24/2020 |
| The upregulation of SPOCK2-encoded Testican2 proteoglycan and of ectodysplasin (EDA) protein was coupled with a down-regulation of EDA2 receptor (EDA2R). | Studies on sporadic non-syndromic thoracic aortic aneurysms: II. Alterations of extra-cellular matrix components and focal adhesion proteins.
Chiarini A, Onorati F, Marconi M, Pasquali A, Patuzzo C, Malashicheva A, Irtyega O, Faggian G, Pignatti PF, Trabetti E, Armato U, Dal Pra I. | 06/15/2019 |
| candidate susceptibility gene for bronchopulmonary dysplasia; lung expression pattern indicates potential role in alveolarization | Identification of SPOCK2 as a susceptibility gene for bronchopulmonary dysplasia.
Hadchouel A, Durrmeyer X, Bouzigon E, Incitti R, Huusko J, Jarreau PH, Lenclen R, Demenais F, Franco-Montoya ML, Layouni I, Patkai J, Bourbon J, Hallman M, Danan C, Delacourt C., Free PMC Article | 01/7/2012 |
| purification and characterization of a recombinant testican-2 expressed in insect cells; the C1q subcomponent of complement component C1 was identified as a potential interacting partner of testican-2 | Purification and characterization of a recombinant human testican-2 expressed in baculovirus-infected Sf9 insect cells.
Pavsic M, Vito T, Lenarcic B. | 01/21/2010 |
| Observational study of gene-disease association. (HuGE Navigator) | See all PubMed (2) articlesGenome-wide analysis identifies 16q deletion associated with survival, molecular subtypes, mRNA expression, and germline haplotypes in breast cancer patients.
Nordgard SH, Johansen FE, Alnaes GI, Bucher E, Syvänen AC, Naume B, Børresen-Dale AL, Kristensen VN. A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.
Grupe A, Li Y, Rowland C, Nowotny P, Hinrichs AL, Smemo S, Kauwe JS, Maxwell TJ, Cherny S, Doil L, Tacey K, van Luchene R, Myers A, Wavrant-De Vrièze F, Kaleem M, Hollingworth P, Jehu L, Foy C, Archer N, Hamilton G, Holmans P, Morris CM, Catanese J, Sninsky J, White TJ, Powell J, Hardy J, O'Donovan M, Lovestone S, Jones L, Morris JC, Thal L, Owen M, Williams J, Goate A. | 04/23/2008 |
| Neurons are a major source of all of the testican family members in the normal brain. Abundant distribution of testican 2 may contribute to glioma invasion by inactivating other testican family members including N-Tes, which all inhibit MT-MMPs. | Testican 2 abrogates inhibition of membrane-type matrix metalloproteinases by other testican family proteins.
Nakada M, Miyamori H, Yamashita J, Sato H. | 01/21/2010 |