| MATR3 pathogenic variants differentially impair its cryptic splicing repression function. | MATR3 pathogenic variants differentially impair its cryptic splicing repression function.
Khan M, Chen XXL, Dias M, Santos JR, Kour S, You J, van Bruggen R, Youssef MMM, Wan YW, Liu Z, Rosenfeld JA, Tan Q, Pandey UB, Yalamanchili HK, Park J. | 05/24/2024 |
| Matrin-3 acts as a potential biomarker and promotes hepatocellular carcinoma progression by interacting with cell cycle-regulating genes. | Matrin-3 acts as a potential biomarker and promotes hepatocellular carcinoma progression by interacting with cell cycle-regulating genes.
He H, Jamal M, Zeng X, Lei Y, Xiao D, Wei Z, Zhang C, Zhang X, Pan S, Ding Q, Tan H, Xie S, Zhang Q., | 04/17/2024 |
| Matrin3 mediates differentiation through stabilizing chromatin loop-domain interactions and YY1 mediated enhancer-promoter interactions. | Matrin3 mediates differentiation through stabilizing chromatin loop-domain interactions and YY1 mediated enhancer-promoter interactions.
Liu T, Zhu Q, Kai Y, Bingham T, Wang S, Cha HJ, Mehta S, Schlaeger TM, Yuan GC, Orkin SH., Free PMC Article | 02/16/2024 |
| The effect on m[6]A methylation writer complex by the reduced MATR3 in pterygium. | The effect on m(6)A methylation writer complex by the reduced MATR3 in pterygium.
Guo Q, Han S. | 12/4/2023 |
| MATR3 is an endogenous inhibitor of DUX4 in FSHD muscular dystrophy. | MATR3 is an endogenous inhibitor of DUX4 in FSHD muscular dystrophy.
Runfola V, Giambruno R, Caronni C, Pannese M, Andolfo A, Gabellini D., Free PMC Article | 10/11/2023 |
| Neuronal activity regulates Matrin 3 abundance and function in a calcium-dependent manner through calpain-mediated cleavage and calmodulin binding. | Neuronal activity regulates Matrin 3 abundance and function in a calcium-dependent manner through calpain-mediated cleavage and calmodulin binding.
Malik AM, Wu JJ, Gillies CA, Doctrove QA, Li X, Huang H, Tank EHM, Shakkottai VG, Barmada S., Free PMC Article | 04/10/2023 |
| LncRNA15691 promotes T-ALL infiltration by upregulating CCR9 via increased MATR3 stability. | LncRNA15691 promotes T-ALL infiltration by upregulating CCR9 via increased MATR3 stability.
Zeng X, Lei Y, Pan S, Sun J, He H, Xiao D, Jamal M, Shen H, Zhou F, Shao L, Zhang Q. | 02/27/2023 |
| Matr3 reshapes m6A modification complex to alleviate macrophage inflammation during atherosclerosis. | Matr3 reshapes m6A modification complex to alleviate macrophage inflammation during atherosclerosis.
Sun Z, Chen W, Wang Z, Wang S, Zan J, Zheng L, Zhao W. | 12/3/2022 |
| Prognostic significance of MATR3 in stage I and II non-small cell lung cancer patients. | Prognostic significance of MATR3 in stage I and II non-small cell lung cancer patients.
Durślewicz J, Klimaszewska-Wiśniewska A, Jóźwicki J, Antosik P, Kozerawski K, Grzanka D, Braun M. | 10/29/2022 |
| Intronic Determinants Coordinate Charme lncRNA Nuclear Activity through the Interaction with MATR3 and PTBP1. | Intronic Determinants Coordinate Charme lncRNA Nuclear Activity through the Interaction with MATR3 and PTBP1.
Desideri F, Cipriano A, Petrezselyova S, Buonaiuto G, Santini T, Kasparek P, Prochazka J, Janson G, Paiardini A, Calicchio A, Colantoni A, Sedlacek R, Bozzoni I, Ballarino M., Free PMC Article | 12/25/2021 |
| MATR3 haploinsufficiency and early-onset neurodegeneration. | MATR3 haploinsufficiency and early-onset neurodegeneration.
Zech M, Seibt A, Zumbaum B, Klee D, Meitinger T, Winkelmann J, Mayatepek E, Wagner M, Distelmaier F. | 12/18/2021 |
| RNA dependent suppression of C9orf72 ALS/FTD associated neurodegeneration by Matrin-3. | RNA dependent suppression of C9orf72 ALS/FTD associated neurodegeneration by Matrin-3.
Ramesh N, Daley EL, Gleixner AM, Mann JR, Kour S, Mawrie D, Anderson EN, Kofler J, Donnelly CJ, Kiskinis E, Pandey UB., Free PMC Article | 11/13/2021 |
| Whole-body muscle MRI of patients with MATR3-associated distal myopathy reveals a distinct pattern of muscular involvement and highlights the value of whole-body examination. | Whole-body muscle MRI of patients with MATR3-associated distal myopathy reveals a distinct pattern of muscular involvement and highlights the value of whole-body examination.
Mensch A, Kraya T, Koester F, Müller T, Stoevesandt D, Zierz S., Free PMC Article | 07/31/2021 |
| Matrin-3 plays an important role in cell cycle and apoptosis for survival in malignant melanoma. | Matrin-3 plays an important role in cell cycle and apoptosis for survival in malignant melanoma.
Kuriyama H, Fukushima S, Kimura T, Okada E, Ishibashi T, Mizuhashi S, Kanemaru H, Kajihara I, Makino K, Miyashita A, Aoi J, Okada S, Ihn H, Kita K. | 06/26/2021 |
| Matrin 3 in neuromuscular disease: physiology and pathophysiology. | Matrin 3 in neuromuscular disease: physiology and pathophysiology.
Malik AM, Barmada SJ., Free PMC Article | 05/29/2021 |
| Knockdown of genes involved in axonal transport enhances the toxicity of human neuromuscular disease-linked MATR3 mutations in Drosophila. | Knockdown of genes involved in axonal transport enhances the toxicity of human neuromuscular disease-linked MATR3 mutations in Drosophila.
Zhao M, Kao CS, Arndt C, Tran DD, Cho WI, Maksimovic K, Chen XXL, Khan M, Zhu H, Qiao J, Peng K, Hong J, Xu J, Kim D, Kim JR, Lee J, van Bruggen R, Yoon WH, Park J. | 05/15/2021 |
| Effect of up-regulation of circMATR3 on the proliferation, metastasis, progression and survival of hypopharyngeal carcinoma. | Effect of up-regulation of circMATR3 on the proliferation, metastasis, progression and survival of hypopharyngeal carcinoma.
Wang Z, Wei P, Wei D, Cao S, Liu H, Chen L, Han X, Zhao X, Liu C, Li G, Yang J, Pan X, Lei D., Free PMC Article | 05/1/2021 |
| Data shows the expression profile of Gle1, MATR3 and FUS genes in Spinal muscular atrophy (SMA), and suggest a critical role of FUS protein in SMA pathogenesis. Note that the authors appear to erroneously refer to the human MATR3 gene (GeneID: 9782) as MART3 (GeneID: 203430) in this publication. | The expression of SMN1, MART3, GLE1 and FUS genes in spinal muscular atrophy.
Alrafiah A, Alghanmi M, Almashhadi S, Aqeel A, Awaji A. | 12/31/2020 |
| N-terminal sequences in MATR3 can mediate phase separation into intranuclear droplet-like structures that can recruit TDP43 under conditions of low RNA binding. | N-terminal sequences in matrin 3 mediate phase separation into droplet-like structures that recruit TDP43 variants lacking RNA binding elements.
Gallego-Iradi MC, Strunk H, Crown AM, Davila R, Brown H, Rodriguez-Lebron E, Borchelt DR., Free PMC Article | 06/27/2020 |
| MATR3 is a splicing activator during PDCD1 exon 3 splicing that operates through binding to enhancer elements ESE3a and ESE3b. | Modulation of PDCD1 exon 3 splicing.
Sun J, Bai J, Jiang T, Gao Y, Hua Y., Free PMC Article | 05/2/2020 |
| Mutant MATR3 causes multisystem proteinopathy in mice. | A mutant MATR3 mouse model to explain multisystem proteinopathy.
Zhang X, Yamashita S, Hara K, Doki T, Tawara N, Ikeda T, Misumi Y, Zhang Z, Matsuo Y, Nagai M, Kurashige T, Maruyama H, Ando Y. | 04/18/2020 |
| identified MATR3 as binding to SNHG1 and the interaction might be involved in splicing events that enhance neuroblastoma progression. | RNA-Binding Proteomics Reveals MATR3 Interacting with lncRNA SNHG1 To Enhance Neuroblastoma Progression.
Yang TW, Sahu D, Chang YW, Hsu CL, Hsieh CH, Huang HC, Juan HF. | 03/14/2020 |
| MATR3 regulates miR-138 in neurons, with important implications for miR-138 regulation during neuronal development, synaptic plasticity and memory-related processes. | The nuclear matrix protein Matr3 regulates processing of the synaptic microRNA-138-5p.
Weiss K, Treiber T, Meister G, Schratt G. | 12/14/2019 |
| The intra-nuclear localization and interaction network of MATR3 is strongly modulated by its RRM2 domain. | Characterization of gene regulation and protein interaction networks for Matrin 3 encoding mutations linked to amyotrophic lateral sclerosis and myopathy.
Iradi MCG, Triplett JC, Thomas JD, Davila R, Crown AM, Brown H, Lewis J, Swanson MS, Xu G, Rodriguez-Lebron E, Borchelt DR., Free PMC Article | 09/21/2019 |
| FUS, EWSR1, TAF15 and MATR3 within the RNAP II/U1 snRNP machinery play distinct roles in the development of amyotrophic lateral sclerosis and spinal muscular atrophy that are more intimately tied to one another than previously thought. | The neurodegenerative diseases ALS and SMA are linked at the molecular level via the ASC-1 complex.
Chi B, O'Connell JD, Iocolano AD, Coady JA, Yu Y, Gangopadhyay J, Gygi SP, Reed R., Free PMC Article | 06/29/2019 |