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    CD63 CD63 molecule [ Homo sapiens (human) ]

    Gene ID: 967, updated on 3-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Arf GTPase-Activating proteins ADAP1 and ARAP1 regulate incorporation of CD63 in multivesicular bodies.

    Arf GTPase-Activating proteins ADAP1 and ARAP1 regulate incorporation of CD63 in multivesicular bodies.
    Suzuki K, Okawa Y, Akter S, Ito H, Shiba Y., Free PMC Article

    06/27/2024
    The subtilisin-like protease furin regulates hemin-induced CD63 surface expression on platelets.

    The subtilisin-like protease furin regulates hemin-induced CD63 surface expression on platelets.
    Dicenta V, Pelzer A, Laspa Z, Castor T, Gawaz MP, Rohlfing AK.

    02/23/2024
    Differential proteomics argues against a general role for CD9, CD81 or CD63 in the sorting of proteins into extracellular vesicles.

    Differential proteomics argues against a general role for CD9, CD81 or CD63 in the sorting of proteins into extracellular vesicles.
    Fan Y, Pionneau C, Cocozza F, Boëlle PY, Chardonnet S, Charrin S, Théry C, Zimmermann P, Rubinstein E., Free PMC Article

    10/20/2023
    Lack of involvement of CD63 and CD9 tetraspanins in the extracellular vesicle content delivery process.

    Lack of involvement of CD63 and CD9 tetraspanins in the extracellular vesicle content delivery process.
    Tognoli ML, Dancourt J, Bonsergent E, Palmulli R, de Jong OG, Van Niel G, Rubinstein E, Vader P, Lavieu G., Free PMC Article

    06/7/2023
    LAMP3/CD63 Expression in Early and Late Endosomes in Human Vaginal Epithelial Cells Is Associated with Enhancement of HSV-2 Infection.

    LAMP3/CD63 Expression in Early and Late Endosomes in Human Vaginal Epithelial Cells Is Associated with Enhancement of HSV-2 Infection.
    Nazli A, Chow R, Zahoor MA, Workenhe ST, Dhawan T, Verschoor C, Kaushic C., Free PMC Article

    12/24/2022
    Aberrant TIMP-1 overexpression in tumor-associated fibroblasts drives tumor progression through CD63 in lung adenocarcinoma.

    Aberrant TIMP-1 overexpression in tumor-associated fibroblasts drives tumor progression through CD63 in lung adenocarcinoma.
    Duch P, Díaz-Valdivia N, Ikemori R, Gabasa M, Radisky ES, Arshakyan M, Gea-Sorlí S, Mateu-Bosch A, Bragado P, Carrasco JL, Mori H, Ramírez J, Teixidó C, Reguart N, Fillat C, Radisky DC, Alcaraz J., Free PMC Article

    09/17/2022
    CD63-positive extracellular vesicles are potential diagnostic biomarkers of pancreatic ductal adenocarcinoma.

    CD63-positive extracellular vesicles are potential diagnostic biomarkers of pancreatic ductal adenocarcinoma.
    Odaka H, Hiemori K, Shimoda A, Akiyoshi K, Tateno H., Free PMC Article

    04/9/2022
    A potential target gene CD63 for different degrees of intervertebral disc degeneration.

    A potential target gene CD63 for different degrees of intervertebral disc degeneration.
    Gao S, Jia S, Fan X, Gao C, Li Q, Wu Y, Meng C., Free PMC Article

    03/5/2022
    CD63-mediated cloaking of VEGF in small extracellular vesicles contributes to anti-VEGF therapy resistance.

    CD63-mediated cloaking of VEGF in small extracellular vesicles contributes to anti-VEGF therapy resistance.
    Ma S, Mangala LS, Hu W, Bayaktar E, Yokoi A, Hu W, Pradeep S, Lee S, Piehowski PD, Villar-Prados A, Wu SY, McGuire MH, Lara OD, Rodriguez-Aguayo C, LaFargue CJ, Jennings NB, Rodland KD, Liu T, Kundra V, Ram PT, Ramakrishnan S, Lopez-Berestein G, Coleman RL, Sood AK., Free PMC Article

    02/12/2022
    Activated steady status and distinctive FcepsilonRI-mediated responsiveness in basophils of atopic dermatitis.

    Activated steady status and distinctive FcεRI-mediated responsiveness in basophils of atopic dermatitis.
    Imamura S, Washio K, Mizuno M, Oda Y, Fukunaga A, Nishigori C.

    01/1/2022
    Platelet-derived extracellular vesicles are increased in sera of Alzheimer's disease patients, as revealed by Tim4-based assays.

    Platelet-derived extracellular vesicles are increased in sera of Alzheimer's disease patients, as revealed by Tim4-based assays.
    Odaka H, Hiemori K, Shimoda A, Akiyoshi K, Tateno H., Free PMC Article

    01/1/2022
    CD63 expression in metastatic melanoma and melanocytic nevi in lymph nodes.

    CD63 expression in metastatic melanoma and melanocytic nevi in lymph nodes.
    Mejia O, Vazquez T, Alexis J.

    12/11/2021
    CD63 is regulated by iron via the IRE-IRP system and is important for ferritin secretion by extracellular vesicles.

    CD63 is regulated by iron via the IRE-IRP system and is important for ferritin secretion by extracellular vesicles.
    Yanatori I, Richardson DR, Dhekne HS, Toyokuni S, Kishi F., Free PMC Article

    12/11/2021
    Regulation of Tumor Metabolism and Extracellular Acidosis by the TIMP-10-CD63 Axis in Breast Carcinoma.

    Regulation of Tumor Metabolism and Extracellular Acidosis by the TIMP-10-CD63 Axis in Breast Carcinoma.
    Najy AJ, Jung YS, Kim S, Fridman R, Kim HC., Free PMC Article

    12/4/2021
    The large extracellular loop of CD63 interacts with gp41 of HIV-1 and is essential for establishing the virological synapse.

    The large extracellular loop of CD63 interacts with gp41 of HIV-1 and is essential for establishing the virological synapse.
    Ivanusic D, Madela K, Bannert N, Denner J., Free PMC Article

    11/6/2021
    CD63 negatively regulates hepatocellular carcinoma development through suppression of inflammatory cytokine-induced STAT3 activation.

    CD63 negatively regulates hepatocellular carcinoma development through suppression of inflammatory cytokine-induced STAT3 activation.
    Yu S, Chen J, Quan M, Li L, Li Y, Gao Y., Free PMC Article

    09/18/2021
    Epstein-Barr Virus LMP1 Modulates the CD63 Interactome.

    Epstein-Barr Virus LMP1 Modulates the CD63 Interactome.
    Cheerathodi M, Nkosi D, Cone AS, York SB, Meckes DG Jr., Free PMC Article

    08/14/2021
    Specificities of exosome versus small ectosome secretion revealed by live intracellular tracking of CD63 and CD9.

    Specificities of exosome versus small ectosome secretion revealed by live intracellular tracking of CD63 and CD9.
    Mathieu M, Névo N, Jouve M, Valenzuela JI, Maurin M, Verweij FJ, Palmulli R, Lankar D, Dingli F, Loew D, Rubinstein E, Boncompain G, Perez F, Théry C., Free PMC Article

    08/7/2021
    Prognostic Value of CD63 Expression in Solid Tumors: A Meta-analysis of the Literature.

    Prognostic Value of CD63 Expression in Solid Tumors: A Meta-analysis of the Literature.
    Koh HM, Jang BG, Kim DC., Free PMC Article

    07/10/2021
    Tetraspanin CD63 independently predicts poor prognosis in colorectal cancer.

    Tetraspanin CD63 independently predicts poor prognosis in colorectal cancer.
    Kaprio T, Hagström J, Andersson LC, Haglund C.

    07/10/2021
    Sequential deletion of CD63 identifies topologically distinct scaffolds for surface engineering of exosomes in living human cells.

    Sequential deletion of CD63 identifies topologically distinct scaffolds for surface engineering of exosomes in living human cells.
    Curley N, Levy D, Do MA, Brown A, Stickney Z, Marriott G, Lu B., Free PMC Article

    06/19/2021
    Resistance Training Diminishes the Expression of Exosome CD63 Protein without Modification of Plasma miR-146a-5p and cfDNA in the Elderly.

    Resistance Training Diminishes the Expression of Exosome CD63 Protein without Modification of Plasma miR-146a-5p and cfDNA in the Elderly.
    Estébanez B, Visavadiya NP, de Paz JA, Whitehurst M, Cuevas MJ, González-Gallego J, Huang CJ., Free PMC Article

    05/8/2021
    A fusion of CD63-BCAR4 identified in lung adenocarcinoma promotes tumorigenicity and metastasis.

    A fusion of CD63-BCAR4 identified in lung adenocarcinoma promotes tumorigenicity and metastasis.
    Bae K, Kim JH, Jung H, Kong SY, Kim YH, Kim S, Lee GK, Lee JS, Lee JJ, Ju YS, Choi YK, Yoon KA., Free PMC Article

    04/24/2021
    Generation of the Rat Monoclonal Antibody Against the Extracellular Domain of Human CD63 by DNA Immunization.

    Generation of the Rat Monoclonal Antibody Against the Extracellular Domain of Human CD63 by DNA Immunization.
    Xu L, Ihara KI, Yoshimura S, Konno D, Tachibana A, Nakanishi T, Tachibana T.

    04/24/2021
    HPV caught in the tetraspanin web?

    HPV caught in the tetraspanin web?
    Finke J, Hitschler L, Boller K, Florin L, Lang T., Free PMC Article

    02/2/2021
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