| Keratin-Positive Giant Cell-Rich Tumor of Bone Harboring an HMGA2::NCOR2 Fusion: Two Cases, Including a Patient With Metastatic Disease, and Review of the Literature. | Keratin-Positive Giant Cell-Rich Tumor of Bone Harboring an HMGA2::NCOR2 Fusion: Two Cases, Including a Patient With Metastatic Disease, and Review of the Literature.
Patton A, Ilaslan H, Armstrong SM, Bakhshwin A, Cheng YW, Minhas F, Fritchie KJ. | 04/23/2024 |
| Nuclear corepressors NCOR1/NCOR2 regulate B cell development, maintain genomic integrity and prevent transformation. | Nuclear corepressors NCOR1/NCOR2 regulate B cell development, maintain genomic integrity and prevent transformation.
Lee RD, Knutson TP, Munro SA, Miller JT, Heltemes-Harris LM, Mullighan CG, Jepsen K, Farrar MA., Free PMC Article | 12/24/2022 |
| Screening of organoids derived from patients with breast cancer implicates the repressor NCOR2 in cytotoxic stress response and antitumor immunity. | Screening of organoids derived from patients with breast cancer implicates the repressor NCOR2 in cytotoxic stress response and antitumor immunity.
Tsai KK, Huang SS, Northey JJ, Liao WY, Hsu CC, Cheng LH, Werner ME, Chuu CP, Chatterjee C, Lakins JN, Weaver VM., Free PMC Article | 07/9/2022 |
| NCOR2 is a novel candidate gene for migraine-epilepsy phenotype. | NCOR2 is a novel candidate gene for migraine-epilepsy phenotype.
Nuottamo ME, Häppölä P, Artto V, Hautakangas H, Pirinen M, Hiekkalinna T, Ellonen P, Lepistö M, Hämäläinen E, International Headache Genetics Consortium (IHGC), FinnGenConsortium, Siren A, Lehesjoki AE, Kallela M, Palotie A, Kaunisto MA, Wessman M. | 05/21/2022 |
| Recurrent Fusion of the Genes for High-mobility Group AT-hook 2 (HMGA2) and Nuclear Receptor Co-repressor 2 (NCOR2) in Osteoclastic Giant Cell-rich Tumors of Bone. | Recurrent Fusion of the Genes for High-mobility Group AT-hook 2 (HMGA2) and Nuclear Receptor Co-repressor 2 (NCOR2) in Osteoclastic Giant Cell-rich Tumors of Bone.
Panagopoulos I, Andersen K, Gorunova L, Lund-Iversen M, Lobmaier I, Heim S., Free PMC Article | 03/19/2022 |
| Methylation statuses of NCOR2, PARK2, and ZSCAN12 signify densities of tumor-infiltrating lymphocytes in gastric carcinoma. | Methylation statuses of NCOR2, PARK2, and ZSCAN12 signify densities of tumor-infiltrating lymphocytes in gastric carcinoma.
Wen X, Jin HY, Li M, Kim Y, Cho NY, Kwak Y, Bae JM, Lee HS, Kang GH., Free PMC Article | 03/5/2022 |
| KPNA1 regulates nuclear import of NCOR2 splice variant BQ323636.1 to confer tamoxifen resistance in breast cancer. | KPNA1 regulates nuclear import of NCOR2 splice variant BQ323636.1 to confer tamoxifen resistance in breast cancer.
Tsoi H, Man EP, Leung MH, Mok KC, Chau KM, Wong LS, Chan WL, Chan SY, Luk MY, Cheng CN, Khoo US., Free PMC Article | 02/26/2022 |
| Reduced NCOR2 expression accelerates androgen deprivation therapy failure in prostate cancer. | Reduced NCOR2 expression accelerates androgen deprivation therapy failure in prostate cancer.
Long MD, Jacobi JJ, Singh PK, Llimos G, Wani SA, Rowsam AM, Rosario SR, Hoogstraat M, Linder S, Kirk J, Affronti HC, Bergman A, Zwart W, Campbell MJ, Smiraglia DJ., Free PMC Article | 02/19/2022 |
| Low NCOR2 levels in multiple myeloma patients drive multidrug resistance via MYC upregulation. | Low NCOR2 levels in multiple myeloma patients drive multidrug resistance via MYC upregulation.
Mori T, Verma R, Nakamoto-Matsubara R, Siu KT, Panaroni C, Fulzele KS, Mukaihara K, Onyewadume C, Maebius A, Kato H, Wong LP, Sadreyev RI, Scadden DT, Raje NS., Free PMC Article | 02/5/2022 |
| Recurrent novel HMGA2-NCOR2 fusions characterize a subset of keratin-positive giant cell-rich soft tissue tumors. | Recurrent novel HMGA2-NCOR2 fusions characterize a subset of keratin-positive giant cell-rich soft tissue tumors.
Agaimy A, Michal M, Stoehr R, Ferrazzi F, Fabian P, Michal M, Franchi A, Haller F, Folpe AL, Kösemehmetoğlu K., Free PMC Article | 01/29/2022 |
| Circular RNA circ-NCOR2 accelerates papillary thyroid cancer progression by sponging miR-516a-5p to upregulate metastasis-associated protein 2 expression. | Circular RNA circ-NCOR2 accelerates papillary thyroid cancer progression by sponging miR-516a-5p to upregulate metastasis-associated protein 2 expression.
Luan S, Fu P, Wang X, Gao Y, Shi K, Guo Y., Free PMC Article | 05/8/2021 |
| Thyroid Hormones, Silencing Mediator for Retinoid and Thyroid Receptors and Prognosis in Primary Breast Cancer. | Thyroid Hormones, Silencing Mediator for Retinoid and Thyroid Receptors and Prognosis in Primary Breast Cancer.
Nisman B, Allweis TM, Carmon E, Kadouri L, Maly B, Maimon O, Meierovich A, Peretz T. | 11/21/2020 |
| These findings demonstrate that BQ323636.1(Splice Variant to NCOR2) can be a reliable biomarker to predict tamoxifen resistance in patients with ER-positive breast cancer | BQ323636.1, a Novel Splice Variant to NCOR2, as a Predictor for Tamoxifen-Resistant Breast Cancer.
Gong C, Man EPS, Tsoi H, Lee TKW, Lee P, Ma ST, Wong LS, Luk MY, Rakha EA, Green AR, Ellis IO, Lam EW, Cheung KL, Khoo US., Free PMC Article | 12/21/2019 |
| Data suggest that the nuclear receptor co-repressor 1/2 protein NCoR-1/NCoR-2 paralogs have been subject to a mix of shared and distinct selective pressures, resulting in the pattern of divergent and convergent alternative-splicing observed in extant species. | Evolution of NCoR-1 and NCoR-2 corepressor alternative mRNA splicing in placental mammals.
Privalsky ML, Goodson ML., Free PMC Article | 12/21/2019 |
| Direct epigenetic repression of the transcription-repressive regulators NCOR2 and ZBTB7A by the histone reader protein HP1gamma leads to activation of protumorigenic genes in lung adenocarcinoma. | HP1γ Promotes Lung Adenocarcinoma by Downregulating the Transcription-Repressive Regulators NCOR2 and ZBTB7A.
Alam H, Li N, Dhar SS, Wu SJ, Lv J, Chen K, Flores ER, Baseler L, Lee MG., Free PMC Article | 08/31/2019 |
| SMRT binding does not activate the cryptic deacetylase activity of HDAC4; class IIa HDACs and the SMRT-HDAC3 complex are coordinated during gene regulation | Structural basis of the specific interaction of SMRT corepressor with histone deacetylase 4.
Park SY, Kim GS, Hwang HJ, Nam TH, Park HS, Song J, Jang TH, Lee YC, Kim JS., Free PMC Article | 07/20/2019 |
| MIR22HG inhibited HCC progression in part through the miR-10a-5p/NCOR2 signaling. | LncRNA MIR22HG inhibits growth, migration and invasion through regulating the miR-10a-5p/NCOR2 axis in hepatocellular carcinoma cells.
Wu Y, Zhou Y, Huan L, Xu L, Shen M, Huang S, Liang L., Free PMC Article | 03/9/2019 |
| this report tried to address the molecular basis for the direct interaction between CSL and SMRT. | OPTHiS Identifies the Molecular Basis of the Direct Interaction between CSL and SMRT Corepressor.
Kim GS, Park HS, Lee YC., Free PMC Article | 12/22/2018 |
| The pregnane X receptor (PXR) and the nuclear receptor corepressor 2 (NCoR2) modulate cell growth in head and neck squamous cell carcinoma | The pregnane X receptor (PXR) and the nuclear receptor corepressor 2 (NCoR2) modulate cell growth in head and neck squamous cell carcinoma.
Rigalli JP, Reichel M, Reuter T, Tocchetti GN, Dyckhoff G, Herold-Mende C, Theile D, Weiss J., Free PMC Article | 05/26/2018 |
| Cellular Differentiation of Human Monocytes Is Regulated by Time-Dependent Interleukin-4 Signaling and the Transcriptional Regulator NCOR2. | Cellular Differentiation of Human Monocytes Is Regulated by Time-Dependent Interleukin-4 Signaling and the Transcriptional Regulator NCOR2.
Sander J, Schmidt SV, Cirovic B, McGovern N, Papantonopoulou O, Hardt AL, Aschenbrenner AC, Kreer C, Quast T, Xu AM, Schmidleithner LM, Theis H, Thi Huong LD, Sumatoh HRB, Lauterbach MAR, Schulte-Schrepping J, Günther P, Xue J, Baßler K, Ulas T, Klee K, Katzmarski N, Herresthal S, Krebs W, Martin B, Latz E, Händler K, Kraut M, Kolanus W, Beyer M, Falk CS, Wiegmann B, Burgdorf S, Melosh NA, Newell EW, Ginhoux F, Schlitzer A, Schultze JL., Free PMC Article | 12/30/2017 |
| The mechanism of IL-6-induced AR activation is mediated through enhancing AR-SRC-1 interaction and inhibiting AR-SMRT interaction. | The co-regulators SRC-1 and SMRT are involved in interleukin-6-induced androgen receptor activation.
Wang Q, Wang H, Ju Q, Ding Z, Ge X, Shi QM, Zhou JL, Zhou XL, Zhang JP, Zhang MR, Yu HM, Xu LC. | 06/10/2017 |
| IL-6-mediated AR antagonism induced by cypermethrin is related to repress the recruitment of co-regulators SRC-1 and SMRT to the AR in a ligand-independent manner | Inhibition effect of cypermethrin mediated by co-regulators SRC-1 and SMRT in interleukin-6-induced androgen receptor activation.
Wang Q, Zhou JL, Wang H, Ju Q, Ding Z, Zhou XL, Ge X, Shi QM, Pan C, Zhang JP, Zhang MR, Yu HM, Xu LC. | 03/25/2017 |
| this study identifies NCOR2 as a new gene for FVC, indicating the importance of further research into the role of vitamin A intake/supplementation and its interactions with related genes in the regulation of FVC. | Association of Forced Vital Capacity with the Developmental Gene NCOR2.
Minelli C, Dean CH, Hind M, Alves AC, Amaral AF, Siroux V, Huikari V, Soler Artigas M, Evans DM, Loth DW, Bossé Y, Postma DS, Sin D, Thompson J, Demenais F, Henderson J, SpiroMeta consortium, CHARGE consortium, Bouzigon E, Jarvis D, Järvelin MR, Burney P., Free PMC Article | 07/16/2016 |
| Molecular basis for the specific interactions between HDAC4 and the SMRT corepressor. | Mutagenesis Study Reveals the Rim of Catalytic Entry Site of HDAC4 and -5 as the Major Binding Surface of SMRT Corepressor.
Kim GS, Jung HE, Kim JS, Lee YC., Free PMC Article | 04/9/2016 |
| SNPs in Notch pathway genes may be predictors of cutaneous melanoma disease-specific survival. | Functional Variants in Notch Pathway Genes NCOR2, NCSTN, and MAML2 Predict Survival of Patients with Cutaneous Melanoma.
Zhang W, Liu H, Liu Z, Zhu D, Amos CI, Fang S, Lee JE, Wei Q., Free PMC Article | 04/2/2016 |