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    CD40LG CD40 ligand [ Homo sapiens (human) ]

    Gene ID: 959, updated on 6-Oct-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    A novel hemizygous CD40L mutation of X-linked hyper IgM syndromes and compound heterozygous DOCK8 mutations of hyper IgE syndromes in two Chinese families.

    A novel hemizygous CD40L mutation of X-linked hyper IgM syndromes and compound heterozygous DOCK8 mutations of hyper IgE syndromes in two Chinese families.
    Guo M, Ma Y, Cai K, Liu X, Liu W, Wang F, Qu N, Liu S.

    08/28/2024
    Advanced computational analysis of CD40LG variants in atypical X-linked hyper-IgM syndrome.

    Advanced computational analysis of CD40LG variants in atypical X-linked hyper-IgM syndrome.
    Pazhanisamy A, Jorge SD, Zimmermann MT, Kitcharoensakkul M, Abdalgani M, Khojah A, Victor C, Rueda C, Urrutia R, Abraham RS.

    10/25/2023
    Disseminated cryptococcosis in two boys with novel mutation of CD40 Ligand-Associated X-linked hyper-IgM syndrome.

    Disseminated cryptococcosis in two boys with novel mutation of CD40 Ligand-Associated X-linked hyper-IgM syndrome.
    Pacharn P, Phongsamart W, Boonyawat B, Jirapongsananuruk O, Visitsunthorn N, Chokephaibulkit K.

    06/15/2023
    Two novel CD40LG gene mutations causing X-linked hyper IgM syndrome in Vietnamese patients.

    Two novel CD40LG gene mutations causing X-linked hyper IgM syndrome in Vietnamese patients.
    Lien NTK, Van Anh NT, Chi LQ, Le NNQ, Huyen TT, Mai NTP, Van Tung N, Hoang NH.

    02/24/2023
    Respiratory infections in X-linked hyper-IgM syndrome with CD40LG mutation: a case series of seven children in China.

    Respiratory infections in X-linked hyper-IgM syndrome with CD40LG mutation: a case series of seven children in China.
    Fan H, Huang L, Yang D, Zhang C, Zeng Q, Yin G, Lu G, Shen K., Free PMC Article

    12/3/2022
    Termination of CD40L co-stimulation promotes human B cell differentiation into antibody-secreting cells.

    Termination of CD40L co-stimulation promotes human B cell differentiation into antibody-secreting cells.
    Marsman C, Verstegen NJ, Streutker M, Jorritsma T, Boon L, Ten Brinke A, van Ham SM., Free PMC Article

    10/22/2022
    RANTES and CD40L under Conditions of Long-Term Physical Exercise: A Potential Link to Adaptive Immunity.

    RANTES and CD40L under Conditions of Long-Term Physical Exercise: A Potential Link to Adaptive Immunity.
    Lenz M, Schönbauer R, Stojkovic S, Lee J, Gatterer C, Lichtenauer M, Paar V, Emich M, Fritzer-Szekeres M, Strametz-Juranek J, Graf S, Sponder M., Free PMC Article

    08/6/2022
    Novel Functions of Integrins as Receptors of CD154: Their Role in Inflammation and Apoptosis.

    Novel Functions of Integrins as Receptors of CD154: Their Role in Inflammation and Apoptosis.
    Hassan GS, Salti S, Mourad W., Free PMC Article

    06/18/2022
    Methyl donor micronutrients, CD40-ligand methylation and disease activity in systemic lupus erythematosus: A cross-sectional association study.

    Methyl donor micronutrients, CD40-ligand methylation and disease activity in systemic lupus erythematosus: A cross-sectional association study.
    Vordenbäumen S, Sokolowski A, Rosenbaum A, Gebhard C, Raithel J, Düsing C, Chehab G, Richter JG, Brinks R, Rehli M, Schneider M., Free PMC Article

    04/30/2022
    Analysis of physical activity and plasma levels of soluble CD40 and CD40L in older people with gastrointestinal tract cancer.

    Analysis of physical activity and plasma levels of soluble CD40 and CD40L in older people with gastrointestinal tract cancer.
    Silva RVDC, Torres LC, da Fonte EJA, Mello MJG, Lima JTO, da Matta MC.

    03/12/2022
    CD40LG mutations in Vietnamese patients with X-linked hyper-IgM syndrome; catastrophic anti-phospholipid syndrome as a new complication.

    CD40LG mutations in Vietnamese patients with X-linked hyper-IgM syndrome; catastrophic anti-phospholipid syndrome as a new complication.
    Phan ANL, Pham TTT, Phan XT, Huynh N, Nguyen TM, Cao CTT, Nguyen DT, Luong KTX, Nguyen TTM, Tran ANK, Pham LTT, Nguyen VVT, Swagemakers S, Bui CB, Van Hagen PM., Free PMC Article

    03/5/2022
    Infectious Complications Predict Premature CD8(+) T-cell Senescence in CD40 Ligand-Deficient Patients.

    Infectious Complications Predict Premature CD8(+) T-cell Senescence in CD40 Ligand-Deficient Patients.
    Shin JJ, Catanzaro J, Yonkof JR, Delmonte O, Sacco K, Shin MS, Reddy S, Whittington PJ, Soffer G, Mustillo PJ, Sullivan KE, Notarangelo LD, Abraham RS, Romberg N, Kang I., Free PMC Article

    01/22/2022
    Simultaneous Inhibition of PD-1 and Stimulation of CD40 Signaling Pathways by Anti-PD-L1/CD40L Bispecific Fusion Protein Synergistically Activate Target and Effector Cells.

    Simultaneous Inhibition of PD-1 and Stimulation of CD40 Signaling Pathways by Anti-PD-L1/CD40L Bispecific Fusion Protein Synergistically Activate Target and Effector Cells.
    Pandey MS, Wang C, Umlauf S, Lin S., Free PMC Article

    01/15/2022
    CD40L-Stimulated B Lymphocytes Are Polarized toward APC Functions after Exposure to IL-4 and IL-21.

    CD40L-Stimulated B Lymphocytes Are Polarized toward APC Functions after Exposure to IL-4 and IL-21.
    Possamaï D, Pagé G, Panès R, Gagnon É, Lapointe R.

    01/8/2022
    [The CD40-CD40L axis: Current and future implications in clinical immunology].", trans "L'axe CD40-CD40L : implications actuelles et futures en immunologie clinique.

    [The CD40-CD40L axis: Current and future implications in clinical immunology].
    Vial G, Gensous N, Duffau P.

    12/4/2021
    Associations of site-specific CD4(+)-T-cell hypomethylation within CD40-ligand promotor and enhancer regions with disease activity of women with systemic lupus erythematosus.

    Associations of site-specific CD4(+)-T-cell hypomethylation within CD40-ligand promotor and enhancer regions with disease activity of women with systemic lupus erythematosus.
    Vordenbäumen S, Rosenbaum A, Gebhard C, Raithel J, Sokolowski A, Düsing C, Chehab G, Richter JG, Brinks R, Rehli M, Schneider M.

    09/4/2021
    The Proinflammatory Soluble CD40 Ligand Is Associated with the Systemic Extent of Stable Atherosclerosis.

    The Proinflammatory Soluble CD40 Ligand Is Associated with the Systemic Extent of Stable Atherosclerosis.
    Pereira-da-Silva T, Napoleão P, Pinheiro T, Selas M, Silva F, Ferreira RC, Carmo MM., Free PMC Article

    08/28/2021
    Expression of CD40 Ligand on T Cells and Soluble CD40 Ligand in Children With Kawasaki Disease: A Single-Center Preliminary Study From North India.

    Expression of CD40 Ligand on T Cells and Soluble CD40 Ligand in Children With Kawasaki Disease: A Single-Center Preliminary Study From North India.
    Jindal AK, Rawat A, Goel S, Shandilya J, Saikia B, Minz RW, Singh S.

    08/21/2021
    CD40L from platelet, endothelial cell, and smooth muscle cell may contribute to the proliferation of tumor cell in intravascular large B cell lymphoma.

    CD40L from platelet, endothelial cell, and smooth muscle cell may contribute to the proliferation of tumor cell in intravascular large B cell lymphoma.
    Kasuya A, Tokura Y, Honda T.

    07/10/2021
    Differential Responsiveness of the Platelet Biomarkers, Systemic CD40 Ligand, CD62P, and Platelet-Derived Growth Factor-BB, to Virally-Suppressive Antiretroviral Therapy.

    Differential Responsiveness of the Platelet Biomarkers, Systemic CD40 Ligand, CD62P, and Platelet-Derived Growth Factor-BB, to Virally-Suppressive Antiretroviral Therapy.
    Steel HC, Venter WDF, Theron AJ, Anderson R, Feldman C, Arulappan N, Rossouw TM., Free PMC Article

    06/26/2021
    Complex preimplantation genetic tests for Robertsonian translocation, HLA, and X-linked hyper IgM syndrome caused by a novel mutation of CD40LG gene.

    Complex preimplantation genetic tests for Robertsonian translocation, HLA, and X-linked hyper IgM syndrome caused by a novel mutation of CD40LG gene.
    Huang S, Niu Y, Li J, Gao M, Zhang Y, Yan J, Ma S, Gao X, Gao Y., Free PMC Article

    05/8/2021
    CD154-expressing CMV-specific T cells associate with freedom from DNAemia and may be protective in seronegative recipients after liver or intestine transplantation.

    CD154-expressing CMV-specific T cells associate with freedom from DNAemia and may be protective in seronegative recipients after liver or intestine transplantation.
    Ashokkumar C, Green M, Soltys K, Michaels M, Mazariegos G, Reyes-Mugica M, Higgs BW, Spishock B, Zaccagnini M, Sethi P, Rzempoluch A, Kepler A, Kachmar P, Remaley L, Winnier J, Jones K, Moir K, Fazzolare T, Jenkins K, Hartle T, Falik R, Ningappa M, Bond G, Khanna A, Ganoza A, Sun Q, Sindhi R.

    02/2/2021
    Decreased mRNA Expressions of CD40L in Patients with Neuromyelitis Optica Spectrum Disorder.

    Decreased mRNA Expressions of CD40L in Patients with Neuromyelitis Optica Spectrum Disorder.
    Shi Z, Feng L, Lian Z, Liu J, Chen H, Du Q, Zhang Y, Zhang Q, Yang M, Zhou H.

    12/5/2020
    Inverse relationship between CD40L expression and cytolytic molecule expression by CD8(+)CXCR5(+) T follicular cytotoxic cells in colorectal cancer.

    Inverse relationship between CD40L expression and cytolytic molecule expression by CD8(+)CXCR5(+) T follicular cytotoxic cells in colorectal cancer.
    Xing J, Li X, E J, Wang C, Wang H.

    11/21/2020
    CD154 inhibits death of T cells via a Cis interaction with the alpha5beta1 integrin.

    CD154 inhibits death of T cells via a Cis interaction with the α5β1 integrin.
    Bachsais M, Salti S, Zaoui K, Hassan GS, Aoudjit F, Mourad W., Free PMC Article

    10/3/2020
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