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    CD40 CD40 molecule [ Homo sapiens (human) ]

    Gene ID: 958, updated on 12-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Frequency of CD40-1C>T polymorphism (rs1883832) and association with response to treatment in children with primary immune thrombocytopenia.

    Frequency of CD40-1C>T polymorphism (rs1883832) and association with response to treatment in children with primary immune thrombocytopenia.
    Ahmed HA, Abdelkreem E, Hamed EO, Abo Elmahassen NM, Younis MAA.

    11/1/2024
    ZG16 enhances the maturation of dendritic cells via induction of CD40 and contributes to the antitumor immunity in pancreatic cancer.

    ZG16 enhances the maturation of dendritic cells via induction of CD40 and contributes to the antitumor immunity in pancreatic cancer.
    Meng H, Li L, Nan M, Ding Y, Li Y, Zhang M.

    10/30/2024
    A call for clinical trials in glioblastoma multiforme for interleukin 4, interleukin 6, interleukin 13 and CD40.

    A call for clinical trials in glioblastoma multiforme for interleukin 4, interleukin 6, interleukin 13 and CD40.
    Aydin S, Darko K, Detchou D, Barrie U.

    09/14/2024
    CD40 is expressed in the subsets of endothelial cells undergoing partial endothelial-mesenchymal transition in tumor microenvironment.

    CD40 is expressed in the subsets of endothelial cells undergoing partial endothelial-mesenchymal transition in tumor microenvironment.
    Takahashi K, Kobayashi M, Katsumata H, Tokizaki S, Anzai T, Ikeda Y, Alcaide DM, Maeda K, Ishihara M, Tahara K, Kubota Y, Itoh F, Park J, Takahashi K, Matsunaga YT, Yoshimatsu Y, Podyma-Inoue KA, Watabe T., Free PMC Article

    02/16/2024
    CD68 Antigen and Cerebral Aneurysms: A Case-Control Study.

    CD68 Antigen and Cerebral Aneurysms: A Case-Control Study.
    Rahmanian A, Salehi A, Kamali-Sarvestani E, Ahrari I, Mohamadhoseini E, Jamali M, Ghahramani S.

    02/2/2024
    A genetic variant in the CD40 gene is related to HBV infection in the Chinese Han population.

    A genetic variant in the CD40 gene is related to HBV infection in the Chinese Han population.
    Wu W, Xu S, Zeng Y, Yu L, Chen T, Shang H, Liu C, Yang B, Ou Q., Free PMC Article

    12/20/2023
    Allele-specific protein binding within the CD40 locus in human synovial fibroblasts and immune cells.

    Allele-specific protein binding within the CD40 locus in human synovial fibroblasts and immune cells.
    Moser L, Laskari K, Ospelt C, Houtman M., Free PMC Article

    11/13/2023
    Platelet factor 4 (PF4) induces cluster of differentiation 40 (CD40) expression in human aortic endothelial cells (HAECs) through the SIRT1/NF-kappaB/p65 signaling pathway.

    Platelet factor 4 (PF4) induces cluster of differentiation 40 (CD40) expression in human aortic endothelial cells (HAECs) through the SIRT1/NF-κB/p65 signaling pathway.
    Zhong M, Wang XH, Zhao Y.

    11/3/2023
    Impact of CD40 gene polymorphisms on the risk of cervical squamous cell carcinoma: a case-control study.

    Impact of CD40 gene polymorphisms on the risk of cervical squamous cell carcinoma: a case-control study.
    Zhu M, Li X, Feng Y, Jia T, Li S, Gong L, Dong S, Kong X, Sun L., Free PMC Article

    09/28/2023
    CD40 Upregulation in the Retina of Patients With Diabetic Retinopathy: Association With TRAF2/TRAF6 Upregulation and Inflammatory Molecule Expression.

    CD40 Upregulation in the Retina of Patients With Diabetic Retinopathy: Association With TRAF2/TRAF6 Upregulation and Inflammatory Molecule Expression.
    Vos S, Aaron R, Weng M, Daw J, Rodriguez-Rivera E, Subauste CS., Free PMC Article

    06/21/2023
    Boosting of tau protein aggregation by CD40 and CD48 gene expression in Alzheimer's disease.

    Boosting of tau protein aggregation by CD40 and CD48 gene expression in Alzheimer's disease.
    Kim SH, Lim KH, Yang S, Joo JY.

    12/31/2022
    The Role of CD40, CD86, and Glutathione S-Transferase Omega 1 in the Pathogenesis of Chronic Obstructive Pulmonary Disease.

    The Role of CD40, CD86, and Glutathione S-Transferase Omega 1 in the Pathogenesis of Chronic Obstructive Pulmonary Disease.
    Sun D, Lin R, Ouyang Y., Free PMC Article

    09/17/2022
    LTBP4, SPP1, and CD40 Variants: Genetic Modifiers of Duchenne Muscular Dystrophy Analyzed in Serbian Patients.

    LTBP4, SPP1, and CD40 Variants: Genetic Modifiers of Duchenne Muscular Dystrophy Analyzed in Serbian Patients.
    Kosac A, Pesovic J, Radenkovic L, Brkusanin M, Radovanovic N, Djurisic M, Radivojevic D, Mladenovic J, Ostojic S, Kovacevic G, Kravljanac R, Savic Pavicevic D, Milic Rasic V., Free PMC Article

    09/3/2022
    A CD40 variant is associated with systemic bone loss among patients with rheumatoid arthritis.

    A CD40 variant is associated with systemic bone loss among patients with rheumatoid arthritis.
    Sghiri R, Benhassine H, Baccouche K, Ghozzi M, Jriri S, Shakoor Z, Almogren A, Slama F, Idriss N, Benlamine Z, Bouajina E, Zemni R.

    05/28/2022
    Genetic polymorphisms of FCGR2A, ORAI1 and CD40 are associated with risk of lung cancer.

    Genetic polymorphisms of FCGR2A, ORAI1 and CD40 are associated with risk of lung cancer.
    He J, Yu L, Qiao Z, Yu B, Liu Y, Ren H.

    04/30/2022
    Analysis of physical activity and plasma levels of soluble CD40 and CD40L in older people with gastrointestinal tract cancer.

    Analysis of physical activity and plasma levels of soluble CD40 and CD40L in older people with gastrointestinal tract cancer.
    Silva RVDC, Torres LC, da Fonte EJA, Mello MJG, Lima JTO, da Matta MC.

    03/12/2022
    Compelling Evidence Linking CD40 Gene With Graves' Disease in the Chinese Han Population.

    Compelling Evidence Linking CD40 Gene With Graves' Disease in the Chinese Han Population.
    Jiang H, Yuan FF, Wang HN, Liu W, Ye XP, Yang SY, Xie HJ, Yu SS, Ma YR, Zhang LL, Zhao SX, Song HD, China Consortium for the Genetics of Autoimmune Thyroid Disease., Free PMC Article

    02/19/2022
    Interleukin-7-dependent nonclassical monocytes and CD40 expression are affected in children with type 1 diabetes.

    Interleukin-7-dependent nonclassical monocytes and CD40 expression are affected in children with type 1 diabetes.
    Hehenkamp P, Hoffmann M, Kummer S, Reinauer C, Döing C, Förtsch K, Enczmann J, Balz V, Mayatepek E, Meissner T, Jacobsen M, Seyfarth J.

    02/12/2022
    Identification of differentially expressed genes and signaling pathways in human conjunctiva and reproductive tract infected with Chlamydia trachomatis.

    Identification of differentially expressed genes and signaling pathways in human conjunctiva and reproductive tract infected with Chlamydia trachomatis.
    Zhu GD, Cao XJ, Li YP, Li JX, Leng ZJ, Xie LM, Guo XG., Free PMC Article

    02/5/2022
    The Intracellular Domain of CD40 is a Potent Costimulatory Element in Chimeric Antigen Receptors.

    The Intracellular Domain of CD40 is a Potent Costimulatory Element in Chimeric Antigen Receptors.
    Levin-Piaeda O, Levin N, Pozner S, Danieli A, Weinstein-Marom H, Gross G.

    01/22/2022
    Role of miR-145-5p/ CD40 in the inflammation and apoptosis of HUVECs induced by PM2.5.

    Role of miR-145-5p/ CD40 in the inflammation and apoptosis of HUVECs induced by PM(2.5).
    Zhang X, Qi W, Shi Y, Li X, Yin J, Huo C, Zhang R, Zhao W, Ye J, Zhou L, Ye L.

    01/1/2022
    CD40 up-regulation on dendritic cells correlates with Th17/Treg imbalance in chronic periodontitis in young population.

    CD40 up-regulation on dendritic cells correlates with Th17/Treg imbalance in chronic periodontitis in young population.
    Su X, Zhang J, Qin X., Free PMC Article

    12/18/2021
    CD40 Pathway and IL-2 Expression Mediate the Differential Outcome of Colorectal Cancer Patients with Different CSF1R c.1085 Genotypes.

    CD40 Pathway and IL-2 Expression Mediate the Differential Outcome of Colorectal Cancer Patients with Different CSF1R c.1085 Genotypes.
    Yeh YM, Lin PC, Su WC, Shen MR., Free PMC Article

    12/18/2021
    The circulating soluble form of the CD40 costimulatory immune checkpoint receptor and liver metastasis risk in rectal cancer.

    The circulating soluble form of the CD40 costimulatory immune checkpoint receptor and liver metastasis risk in rectal cancer.
    Meltzer S, Torgunrud A, Abrahamsson H, Solbakken AM, Flatmark K, Dueland S, Bakke KM, Bousquet PA, Negård A, Johansen C, Lyckander LG, Larsen FO, Schou JV, Redalen KR, Ree AH., Free PMC Article

    12/11/2021
    C4b-binding protein alpha-chain enhances antitumor immunity by facilitating the accumulation of tumor-infiltrating lymphocytes in the tumor microenvironment in pancreatic cancer.

    C4b-binding protein α-chain enhances antitumor immunity by facilitating the accumulation of tumor-infiltrating lymphocytes in the tumor microenvironment in pancreatic cancer.
    Sasaki K, Takano S, Tomizawa S, Miyahara Y, Furukawa K, Takayashiki T, Kuboki S, Takada M, Ohtsuka M., Free PMC Article

    12/11/2021
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