| Icb-1 expression inhibits growth and fulvestrant response of breast cancer cells and affects survival of breast cancer patients. | Icb-1 expression inhibits growth and fulvestrant response of breast cancer cells and affects survival of breast cancer patients.
Riedmeier M, Skrzypczak M, Schüler-Toprak S, Ortmann O, Treeck O. | 11/13/2021 |
| SNP rs1467465 of the human gene icb-1 might affect susceptibility to ovarian cancer. | Icb-1 gene polymorphism rs1467465 is associated with susceptibility to ovarian cancer.
Schüler S, Lattrich C, Skrzypczak M, Fehm T, Ortmann O, Treeck O., Free PMC Article | 10/24/2015 |
| Loss of icb-1 expression accelerated proliferation of SK-OV-3, OVCAR-3 and OAW-42 cells and led to upregulation of ovarian cancer biomarkers like KLK10 and CLDN16. | icb-1 Gene counteracts growth of ovarian cancer cell lines.
Treeck O, Schüler S, Häring J, Skrzypczak M, Lattrich C, Ortmann O. | 08/3/2013 |
| Data of this study suggest that icb-1 might exert a tumor-suppressor function in breast cancer and that its loss might confer relative resistance of breast cancer cells to apoptotic drugs. | Network analysis of icb-1 gene function in human breast cancer cells.
Treeck O, Belgutay D, Häring J, Schüler S, Lattrich C, Ortmann O. | 11/17/2012 |
| Themis2 and Themis1 exhibit the same potential to restore T cell development and T cell receptor-mediated signaling in Themis1-deficient mice. | Interchangeability of Themis1 and Themis2 in thymocyte development reveals two related proteins with conserved molecular function.
Lesourne R, Zvezdova E, Song KD, El-Khoury D, Uehara S, Barr VA, Samelson LE, Love PE., Free PMC Article | 10/20/2012 |
| These findings together with the observed co-expression of icb-1 with E-cadherin in breast cancer samples support an important role of the icb-1 gene in cancer cell differentiation. | Silencing of the icb-1 gene inhibits the induction of differentiation-associated genes by vitamin D3 and all-trans retinoic acid in gynecological cancer cells.
Haselberger M, Springwald A, Konwisorz A, Lattrich C, Goerse R, Ortmann O, Treeck O. | 08/20/2011 |
| Data show that a highly significant positive correlation of icb-1 transcript levels with c-erbB2 (HER2) expression (p <.0001). | Icb-1 Gene expression is elevated in human endometrial adenocarcinoma and is closely associated with HER2 expression.
Springwald A, Lattrich C, Skrzypczak M, Goerse R, Ortmann O, Treeck O. | 10/30/2010 |
| Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR., Free PMC Article | 06/30/2010 |
| Identification of ICB-1 as a new player in endocrine-related cancer. | Knockdown of ICB-1 gene enhanced estrogen responsiveness of ovarian and breast cancer cells.
Konwisorz A, Springwald A, Haselberger M, Goerse R, Ortmann O, Treeck O. | 06/28/2010 |
| Data suggest that SNP rs1467465 of human gene icb-1 might affect breast cancer susceptibility. | Single nucleotide polymorphisms in human gene icb-1 and breast cancer susceptibility.
Springwald A, Lattrich C, Seitz S, Ortmann O, Treeck O, Springwald A, Lattrich C, Seitz S, Ortmann O, Treeck O. | 01/21/2010 |
| Observational study of gene-disease association. (HuGE Navigator) | Single nucleotide polymorphisms in human gene icb-1 and breast cancer susceptibility.
Springwald A, Lattrich C, Seitz S, Ortmann O, Treeck O, Springwald A, Lattrich C, Seitz S, Ortmann O, Treeck O. | 04/8/2009 |
| The novel interferon-gamma inducible gene icb-1 is identified and its effects on the response of ovarian cancer cells to interferon-gamma are described | Expression of icb-1 gene is interferon-gamma inducible in breast and ovarian cancer cell lines and affects the IFN gamma-response of SK-OV-3 ovarian cancer cells.
Treeck O, Kindzorra I, Pauser K, Treeck L, Ortmann O. | 01/21/2010 |
| Increased icb-1 mRNA levels could be observed both in monocytic and granulocytic differentiation in maturing HL-60 cells. | Detection of increased icb-1 transcript levels in maturing HL-60 cells: a novel marker for granulocytic and monocytic in vitro differentiation.
Treeck O, Odani T, Itoh N, Imai H, Fujita S, Kohroki J, Nakanishi T, Diedrich K, Ortmann O, Tanaka K, Vollmer G. | 01/21/2010 |