| METTL3 suppresses invasion of lung cancer via SH3BP5 m6A modification. | METTL3 suppresses invasion of lung cancer via SH3BP5 m6A modification.
Zhang B, Qian R, Li X. | 02/1/2024 |
| Novel blood-based hypomethylation of SH3BP5 is associated with very early-stage lung adenocarcinoma. | Novel blood-based hypomethylation of SH3BP5 is associated with very early-stage lung adenocarcinoma.
Qiao R, Zhong R, Liu C, Di F, Zhang Z, Wang L, Xu T, Wang Y, Dai L, Gu W, Han B, Yang R. | 05/14/2022 |
| Tankyrase regulates epithelial lumen formation via suppression of Rab11 GEFs. | Tankyrase regulates epithelial lumen formation via suppression of Rab11 GEFs.
Chandrakumar AA, Coyaud É, Marshall CB, Ikura M, Raught B, Rottapel R., Free PMC Article | 10/9/2021 |
| trans-Fatty acids facilitate DNA damage-induced apoptosis through the mitochondrial JNK-Sab-ROS positive feedback loop. | trans-Fatty acids facilitate DNA damage-induced apoptosis through the mitochondrial JNK-Sab-ROS positive feedback loop.
Hirata Y, Inoue A, Suzuki S, Takahashi M, Matsui R, Kono N, Noguchi T, Matsuzawa A., Free PMC Article | 11/21/2020 |
| Study found that expression of SH3BP5 was enhanced in acute myeloid leukemia (AML) cells and was negatively correlated with patients survival. Elevated expression of SH3BP5 was an independent prognostic factor for AML patients. Furthermore, SH3BP5-mediated activation of JNK-BAD signaling contributes to the survival of AML cells. | Elevated SH3BP5 Correlates with Poor Outcome and Contributes to the Growth of Acute Myeloid Leukemia Cells.
Li M, Hao S, Li C, Xiao H, Sun L, Yu Z, Zhang N, Xiong Y, Zhao D, Yin Y., Free PMC Article | 07/18/2020 |
| SH3 domain binding protein 5 (Sab) expression is reduced in ovarian cancer (OC), suggesting that Sab may be a prognostic biomarker to discern personalized treatments for OC patients. | Sab concentrations indicate chemotherapeutic susceptibility in ovarian cancer cell lines.
Paudel I, Hernandez SM, Portalatin GM, Chambers TP, Chambers JW. | 06/8/2019 |
| SH3BP5, LMO3, and SNAP25 were expressed in diffuse large B-cell lymphoma cells and associated with clinical features. | Expressions of SH3BP5, LMO3, and SNAP25 in diffuse large B-cell lymphoma cells and their association with clinical features.
Kobayashi K, Yamaguchi M, Miyazaki K, Imai H, Yokoe K, Ono R, Nosaka T, Katayama N., Free PMC Article | 11/11/2017 |
| REI/SH3BP5 protein family is conserved in evolution and is a group of new guanine nucleotide exchange factors for Rab11. | REI/SH3BP5 protein family: New GEFs for Rab11.
Sato K, Sakaguchi A, Sato M., Free PMC Article | 12/17/2016 |
| The interplay of p-JNK with mitochondrial Sab leads to impaired respiration, ROS production, sustained JNK activation, and apoptosis. | Sab (Sh3bp5) dependence of JNK mediated inhibition of mitochondrial respiration in palmitic acid induced hepatocyte lipotoxicity.
Win S, Than TA, Le BH, García-Ruiz C, Fernandez-Checa JC, Kaplowitz N., Free PMC Article | 04/23/2016 |
| SH3BP5 binds to JNK and directly inhibits JNK through its two putative mitogen-activated protein kinase interaction motifs (KIMs). | SH3-binding protein 5 mediates the neuroprotective effect of the secreted bioactive peptide humanin by inhibiting c-Jun NH2-terminal kinase.
Takeshita Y, Hashimoto Y, Nawa M, Uchino H, Matsuoka M., Free PMC Article | 11/16/2013 |
| mitochondrial protein Sab is phosphorylated by stress-activated protein kinase 3 | Phosphorylation of the mitochondrial protein Sab by stress-activated protein kinase 3.
Court NW, Kuo I, Quigley O, Bogoyevitch MA. | 01/21/2010 |