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    SLIT2 slit guidance ligand 2 [ Homo sapiens (human) ]

    Gene ID: 9353, updated on 17-Jun-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    circVAPA-rich small extracellular vesicles derived from gastric cancer promote neural invasion by inhibiting SLIT2 expression in neuronal cells.

    circVAPA-rich small extracellular vesicles derived from gastric cancer promote neural invasion by inhibiting SLIT2 expression in neuronal cells.
    Xia Y, Jiang T, Li Y, Gu C, Lv J, Lu C, Xu P, Fang L, Chen Z, Liu H, Zhang D, Xu H, Yang L, Xu Z, Wang L.

    06/8/2024
    Recombinant Slit2 attenuates tracheal fibroblast activation in benign central airway obstruction by inhibiting the TGF-beta1/Smad3 signaling pathway.

    Recombinant Slit2 attenuates tracheal fibroblast activation in benign central airway obstruction by inhibiting the TGF-β1/Smad3 signaling pathway.
    He C, Gu L, Li A, Li Y, Xiao R, Liao J, Mu J, Gan Y, Peng M, Mohan G, Liu W, Xu L, Guo S.

    02/28/2024
    The chemorepellent, SLIT2, bolsters innate immunity against Staphylococcus aureus.

    The chemorepellent, SLIT2, bolsters innate immunity against Staphylococcus aureus.
    Bhosle VK, Sun C, Patel S, Ho TWW, Westman J, Ammendolia DA, Langari FM, Fine N, Toepfner N, Li Z, Sharma M, Glogauer J, Capurro MI, Jones NL, Maynes JT, Lee WL, Glogauer M, Grinstein S, Robinson LA., Free PMC Article

    10/10/2023
    Bone marrow mesenchymal stem cell-derived exosomal microRNA-382 promotes osteogenesis in osteoblast via regulation of SLIT2.

    Bone marrow mesenchymal stem cell-derived exosomal microRNA-382 promotes osteogenesis in osteoblast via regulation of SLIT2.
    Su H, Yang Y, Lv W, Li X, Zhao B., Free PMC Article

    03/17/2023
    SLIT2 promoter hypermethylation predicts disease progression in chronic myeloid leukemia.

    SLIT2 promoter hypermethylation predicts disease progression in chronic myeloid leukemia.
    Wu DL, Wang Y, Zhang TJ, Chu MQ, Xu ZJ, Yuan Q, Ma JC, Lin J, Qian J, Zhou JD., Free PMC Article

    12/3/2022
    RNA m6A reader IGF2BP3 promotes metastasis of triple-negative breast cancer via SLIT2 repression.

    RNA m6A reader IGF2BP3 promotes metastasis of triple-negative breast cancer via SLIT2 repression.
    Jiang T, He X, Zhao Z, Zhang X, Wang T, Jia L.

    10/22/2022
    Slit guidance ligand 2 promotes the inflammatory response of periodontitis through activation of the NF-kappaB signaling pathway.

    Slit guidance ligand 2 promotes the inflammatory response of periodontitis through activation of the NF-κB signaling pathway.
    Sun H, Li Z, Fan C, Liu S, Yan K, Huang G, Li S.

    07/30/2022
    The Role of Slit-2 in Gestational Diabetes Mellitus and Its Effect on Pregnancy Outcome.

    The Role of Slit-2 in Gestational Diabetes Mellitus and Its Effect on Pregnancy Outcome.
    Wang Y, Zhao S, Peng W, Chen Y, Chi J, Che K, Wang Y., Free PMC Article

    07/23/2022
    Genomic evolution and the impact of SLIT2 mutation in relapsed intrahepatic cholangiocarcinoma.

    Genomic evolution and the impact of SLIT2 mutation in relapsed intrahepatic cholangiocarcinoma.
    Zhou SL, Luo CB, Song CL, Zhou ZJ, Xin HY, Hu ZQ, Sun RQ, Fan J, Zhou J.

    05/14/2022
    Ductular reaction promotes intrahepatic angiogenesis through Slit2-Roundabout 1 signaling.

    Ductular reaction promotes intrahepatic angiogenesis through Slit2-Roundabout 1 signaling.
    Coll M, Ariño S, Martínez-Sánchez C, Garcia-Pras E, Gallego J, Moles A, Aguilar-Bravo B, Blaya D, Vallverdú J, Rubio-Tomás T, Lozano JJ, Pose E, Graupera I, Fernández-Vidal A, Pol A, Bataller R, Geng JG, Ginès P, Fernandez M, Sancho-Bru P., Free PMC Article

    03/5/2022
    Slit2-Mediated Metabolic Reprogramming in Bone Marrow-Derived Macrophages Enhances Antitumor Immunity.

    Slit2-Mediated Metabolic Reprogramming in Bone Marrow-Derived Macrophages Enhances Antitumor Immunity.
    Kaul K, Benej M, Mishra S, Ahirwar DK, Yadav M, Stanford KI, Jacob NK, Denko NC, Ganju RK., Free PMC Article

    02/26/2022
    Slit2 Inhibits Breast Cancer Metastasis by Activating M1-Like Phagocytic and Antifibrotic Macrophages.

    Slit2 Inhibits Breast Cancer Metastasis by Activating M1-Like Phagocytic and Antifibrotic Macrophages.
    Ahirwar DK, Charan M, Mishra S, Verma AK, Shilo K, Ramaswamy B, Ganju RK., Free PMC Article

    01/8/2022
    Role of Slit2 upregulation in recurrent miscarriage through regulation of stromal decidualization.

    Role of Slit2 upregulation in recurrent miscarriage through regulation of stromal decidualization.
    Chen J, Liu J, Gao S, Qiu Y, Wang Y, Zhang Y, Gao L, Qi G, Wu Y, Lash GE, Li P.

    12/11/2021
    A Study Based on the Correlation Between Slit2/Robo1 Signaling Pathway Proteins and Polymyositis/Dermatomyositis.

    A Study Based on the Correlation Between Slit2/Robo1 Signaling Pathway Proteins and Polymyositis/Dermatomyositis.
    Chai KX, Chen YQ, Kong LS, Fan PL, Yuan X, Yang J.

    11/27/2021
    Placental multipotent mesenchymal stromal cell-derived Slit2 may regulate macrophage motility during placental infection.

    Placental multipotent mesenchymal stromal cell-derived Slit2 may regulate macrophage motility during placental infection.
    Chen CP, Wang LK, Chen CY, Chen CY, Wu YH.

    11/22/2021
    The neurorepellent, Slit2, prevents macrophage lipid loading by inhibiting CD36-dependent binding and internalization of oxidized low-density lipoprotein.

    The neurorepellent, Slit2, prevents macrophage lipid loading by inhibiting CD36-dependent binding and internalization of oxidized low-density lipoprotein.
    Yusuf B, Mukovozov I, Patel S, Huang YW, Liu GY, Reddy EC, Skrtic M, Glogauer M, Robinson LA., Free PMC Article

    11/13/2021
    Slit2 is a potential biomarker for renal impairment in systemic lupus erythematosus.

    Slit2 is a potential biomarker for renal impairment in systemic lupus erythematosus.
    Zhang Y, Hu L, Li X, Chen L, Yang X.

    10/23/2021
    Exome sequencing identifies SLIT2 variants in primary CNS lymphoma.

    Exome sequencing identifies SLIT2 variants in primary CNS lymphoma.
    Kaulen LD, Erson-Omay EZ, Henegariu O, Karschnia P, Huttner A, Günel M, Baehring JM.

    09/25/2021
    Expression of the axon guidance factor Slit2 and its receptor Robo1 in patients with Hirschsprung disease: An observational study.

    Expression of the axon guidance factor Slit2 and its receptor Robo1 in patients with Hirschsprung disease: An observational study.
    Kong M, Zhou T, Xiang B., Free PMC Article

    09/4/2021
    Crosstalk between the activated Slit2-Robo1 pathway and TGF-beta1 signalling promotes cardiac fibrosis.

    Crosstalk between the activated Slit2-Robo1 pathway and TGF-β1 signalling promotes cardiac fibrosis.
    Liu Y, Yin Z, Xu X, Liu C, Duan X, Song Q, Tuo Y, Wang C, Yang J, Yin S., Free PMC Article

    07/24/2021
    Overexpression of Slit2 decreases neuronal excitotoxicity, accelerates glymphatic clearance, and improves cognition in a multiple microinfarcts model.

    Overexpression of Slit2 decreases neuronal excitotoxicity, accelerates glymphatic clearance, and improves cognition in a multiple microinfarcts model.
    He XF, Li G, Li LL, Li MY, Liang FY, Chen X, Hu XQ., Free PMC Article

    07/10/2021
    Structural insights and evaluation of the potential impact of missense variants on the interactions of SLIT2 with ROBO1/4 in cancer progression.

    Structural insights and evaluation of the potential impact of missense variants on the interactions of SLIT2 with ROBO1/4 in cancer progression.
    Sengupta D, Bhattacharya G, Ganguli S, Sengupta M., Free PMC Article

    05/1/2021
    TUG1 Represses Apoptosis, Autophagy, and Inflammatory Response by Regulating miR-27a-3p/SLIT2 in Lipopolysaccharide-Treated Vascular Endothelial Cells.

    TUG1 Represses Apoptosis, Autophagy, and Inflammatory Response by Regulating miR-27a-3p/SLIT2 in Lipopolysaccharide-Treated Vascular Endothelial Cells.
    Dong Y, Fan G, Li Y, Zhou Q.

    03/13/2021
    Tumoural activation of TLR3-SLIT2 axis in endothelium drives metastasis.

    Tumoural activation of TLR3-SLIT2 axis in endothelium drives metastasis.
    Tavora B, Mederer T, Wessel KJ, Ruffing S, Sadjadi M, Missmahl M, Ostendorf BN, Liu X, Kim JY, Olsen O, Welm AL, Goodarzi H, Tavazoie SF., Free PMC Article

    12/19/2020
    Slit2 May Underlie Divergent Induction by Thyrotropin of IL-23 and IL-12 in Human Fibrocytes.

    Slit2 May Underlie Divergent Induction by Thyrotropin of IL-23 and IL-12 in Human Fibrocytes.
    Fernando R, Atkins SJ, Smith TJ., Free PMC Article

    10/24/2020
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