| Structure and mechanisms of transport of human Asc1/CD98hc amino acid transporter. | Structure and mechanisms of transport of human Asc1/CD98hc amino acid transporter.
Rullo-Tubau J, Martinez-Molledo M, Bartoccioni P, Puch-Giner I, Arias Á, Saen-Oon S, Stephan-Otto Attolini C, Artuch R, Díaz L, Guallar V, Errasti-Murugarren E, Palacín M, Llorca O., Free PMC Article | 04/10/2024 |
| LINC00668 promoted non-small lung cancer progression by miR-518c-3p/TRIP4 axis. | LINC00668 promoted non-small lung cancer progression by miR-518c-3p/TRIP4 axis.
Lu Z, Xiao Z, Wang Q, Pan C, Xia Y, Wu W, Chen L. | 12/18/2023 |
| ASC1 complex related conditions: Two novel paediatric patients with TRIP4 pathogenic variants and review of literature. | ASC1 complex related conditions: Two novel paediatric patients with TRIP4 pathogenic variants and review of literature.
Dembour A, Destrée A, Deprez M, Kadhim H, Karadurmus D, Froment O, Deconinck N, Lederer D. | 04/16/2022 |
| Inherited Defects of the ASC-1 Complex in Congenital Neuromuscular Diseases. | Inherited Defects of the ASC-1 Complex in Congenital Neuromuscular Diseases.
Meunier J, Villar-Quiles RN, Duband-Goulet I, Ferreiro A., Free PMC Article | 07/17/2021 |
| MicroRNA-518-3p suppresses cell proliferation, invasiveness, and migration in colorectal cancer via targeting TRIP4. | MicroRNA-518-3p suppresses cell proliferation, invasiveness, and migration in colorectal cancer via targeting TRIP4.
Yang H, Ren J, Bai Y, Jiang J, Xiao S. | 05/22/2021 |
| results expand the spectrum of TRIP4-associated disease to include mild adult forms, associate ASC-1 depletion with isolated primary muscle involvement, and establish TRIP4 as a causative gene for several congenital muscle diseases, including nemaline, core, centronuclear, and cytoplasmic-body myopathies. They also identify ASC-1 as a novel cell cycle regulator with a key role in cell proliferation. | ASC-1 Is a Cell Cycle Regulator Associated with Severe and Mild Forms of Myopathy.
Villar-Quiles RN, Catervi F, Cabet E, Juntas-Morales R, Genetti CA, Gidaro T, Koparir A, Yüksel A, Coppens S, Deconinck N, Pierce-Hoffman E, Lornage X, Durigneux J, Laporte J, Rendu J, Romero NB, Beggs AH, Servais L, Cossée M, Olivé M, Böhm J, Duband-Goulet I, Ferreiro A., Free PMC Article | 05/23/2020 |
| TRIP4 promotes tumor growth and metastasis and regulates radiosensitivity of cervical cancer by activating MAPK, PI3K/AKT, and hTERT signaling. | TRIP4 promotes tumor growth and metastasis and regulates radiosensitivity of cervical cancer by activating MAPK, PI3K/AKT, and hTERT signaling.
Che Y, Li Y, Zheng F, Zou K, Li Z, Chen M, Hu S, Tian C, Yu W, Guo W, Luo M, Deng W, Zou L. | 02/29/2020 |
| Study showed that TRIP4 promoted melanoma growth through modulation of COX-2 and iNOS expression partially by activating NF-kappaB signaling indirectly and partially by the direct anchoring of itself at COX-2 and iNOS promoter via synergy with p300. Clinical data showed that high expression of TRIP4 was positively correlated with increased expression of COX-2 and iNOS and predicted poor prognosis in melanoma patients. | The Tumor-Promoting Role of TRIP4 in Melanoma Progression and its Involvement in Response to BRAF-Targeted Therapy.
Hao J, Xu H, Luo M, Yu W, Chen M, Liao Y, Zhang C, Zhao X, Jiang W, Hou S, Feng X, Zou K, Chen Y, Huang W, Guo W, Kang L, Deng W. | 03/30/2019 |
| Reports reveal the first TRIP4 mutation defining a novel form of congenital muscle disease and establish the importance of ASC-1 in human skeletal muscle, identify transcriptional co-regulation as novel pathophysiological pathway, define ASC-1 as a regulator of late myogenic differentiation and suggest defects in myotube growth as a novel myopathic mechanism. | The transcription coactivator ASC-1 is a regulator of skeletal myogenesis, and its deficiency causes a novel form of congenital muscle disease.
Davignon L, Chauveau C, Julien C, Dill C, Duband-Goulet I, Cabet E, Buendia B, Lilienbaum A, Rendu J, Minot MC, Guichet A, Allamand V, Vadrot N, Fauré J, Odent S, Lazaro L, Leroy JP, Marcorelles P, Dubourg O, Ferreiro A. | 12/17/2016 |
| GWAS in a large Spanish sample identifies TRIP4 (rs74615166) as a significant locus for Alzheimer's disease risk. | Follow-up of loci from the International Genomics of Alzheimer's Disease Project identifies TRIP4 as a novel susceptibility gene.
Ruiz A, Heilmann S, Becker T, Hernández I, Wagner H, Thelen M, Mauleón A, Rosende-Roca M, Bellenguez C, Bis JC, Harold D, Gerrish A, Sims R, Sotolongo-Grau O, Espinosa A, Alegret M, Arrieta JL, Lacour A, Leber M, Becker J, Lafuente A, Ruiz S, Vargas L, Rodríguez O, Ortega G, Dominguez MA, IGAP, Mayeux R, Haines JL, Pericak-Vance MA, Farrer LA, Schellenberg GD, Chouraki V, Launer LJ, van Duijn C, Seshadri S, Antúnez C, Breteler MM, Serrano-Ríos M, Jessen F, Tárraga L, Nöthen MM, Maier W, Boada M, Ramírez A., Free PMC Article | 03/7/2015 |
| Gastrin activates paracrine networks leading to induction of PAI-2 via MAZ and ASC-1. | Gastrin activates paracrine networks leading to induction of PAI-2 via MAZ and ASC-1.
Almeida-Vega S, Catlow K, Kenny S, Dimaline R, Varro A., Free PMC Article | 01/21/2010 |