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    CD9 CD9 molecule [ Homo sapiens (human) ]

    Gene ID: 928, updated on 2-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    CD9 promotes TbetaR2-TbetaR1 association driving the transition of human dermal fibroblasts to myofibroblast under hypoxia.

    CD9 promotes TβR2-TβR1 association driving the transition of human dermal fibroblasts to myofibroblast under hypoxia.
    Huang W, Zhang Z, Li X, Zheng Q, Wu C, Liu L, Chen Y, Zhang J, Jiang X., Free PMC Article

    10/5/2024
    Immunohistochemical analysis of CD9, CD29 and epithelial to mesenchymal transition in triple-negative breast cancer.

    Immunohistochemical analysis of CD9, CD29 and epithelial to mesenchymal transition in triple-negative breast cancer.
    Ondruššek R, Brychtová S, Bezděková M, Bouchalova K, Vávrová Z, Souček K, Bouchal J.

    10/4/2024
    CD9 shapes glucocorticoid sensitivity in pediatric B-cell precursor acute lymphoblastic leukemia.

    CD9 shapes glucocorticoid sensitivity in pediatric B-cell precursor acute lymphoblastic leukemia.
    Zhang C, Chan KYY, Ng WH, Cheung JTK, Sun Q, Wang H, Chung PY, Cheng FWT, Leung AWK, Zhang XB, Lee PY, Fok SP, Lin G, Poon ENY, Feng JH, Tang YL, Luo XQ, Huang LB, Kang W, Tang PMK, Huang J, Chen C, Dong J, Mejstrikova E, Cai J, Liu Y, Shen S, Yang JJ, Yuen PMP, Li CK, Leung KT., Free PMC Article

    09/12/2024
    High expression of CD9 and Epidermal Growth Factor Receptor promotes the development of tongue cancer.

    High expression of CD9 and Epidermal Growth Factor Receptor promotes the development of tongue cancer.
    Suhasini PC, Bhat V, Shetty SS, Shetty PK, Roopashree PG, Kumari NS.

    03/14/2024
    CD9 co-operation with syndecan-1 is required for a major staphylococcal adhesion pathway.

    CD9 co-operation with syndecan-1 is required for a major staphylococcal adhesion pathway.
    Green LR, Issa R, Albaldi F, Urwin L, Thompson R, Khalid H, Turner CE, Ciani B, Partridge LJ, Monk PN., Free PMC Article

    02/16/2024
    Prognostic implications of CD9 in childhood acute lymphoblastic leukemia: insights from a nationwide multicenter study in China.

    Prognostic implications of CD9 in childhood acute lymphoblastic leukemia: insights from a nationwide multicenter study in China.
    Leung KT, Cai J, Liu Y, Chan KYY, Shao J, Yang H, Hu Q, Xue Y, Wu X, Guo X, Zhai X, Wang N, Li X, Tian X, Li Z, Xue N, Guo Y, Wang L, Zou Y, Xiao P, He Y, Jin R, Tang J, Yang JJ, Shen S, Pui CH, Li CK., Free PMC Article

    02/13/2024
    Differential proteomics argues against a general role for CD9, CD81 or CD63 in the sorting of proteins into extracellular vesicles.

    Differential proteomics argues against a general role for CD9, CD81 or CD63 in the sorting of proteins into extracellular vesicles.
    Fan Y, Pionneau C, Cocozza F, Boëlle PY, Chardonnet S, Charrin S, Théry C, Zimmermann P, Rubinstein E., Free PMC Article

    10/20/2023
    Small extracellular vesicles have distinct CD81 and CD9 tetraspanin expression profiles in plasma from rheumatoid arthritis patients.

    Small extracellular vesicles have distinct CD81 and CD9 tetraspanin expression profiles in plasma from rheumatoid arthritis patients.
    Rydland A, Heinicke F, Flåm ST, Mjaavatten MD, Lie BA., Free PMC Article

    10/5/2023
    Prognostic significance of tetraspanin CD9 and oncogenic epidermal growth factor receptor in tongue squamous cell carcinoma survival.

    Prognostic significance of tetraspanin CD9 and oncogenic epidermal growth factor receptor in tongue squamous cell carcinoma survival.
    P C S, Shetty SS, Kumari N S, Shetty VV, Shetty P, Rao C, Shetty PK.

    08/19/2023
    Lack of involvement of CD63 and CD9 tetraspanins in the extracellular vesicle content delivery process.

    Lack of involvement of CD63 and CD9 tetraspanins in the extracellular vesicle content delivery process.
    Tognoli ML, Dancourt J, Bonsergent E, Palmulli R, de Jong OG, Van Niel G, Rubinstein E, Vader P, Lavieu G., Free PMC Article

    06/7/2023
    Mouse Spinal Cord Vascular Transcriptome Analysis Identifies CD9 and MYLIP as Injury-Induced Players.

    Mouse Spinal Cord Vascular Transcriptome Analysis Identifies CD9 and MYLIP as Injury-Induced Players.
    Martins I, Neves-Silva D, Ascensão-Ferreira M, Dias AF, Ribeiro D, Isidro AF, Quitéria R, Paramos-de-Carvalho D, Barbosa-Morais NL, Saúde L., Free PMC Article

    04/14/2023
    Neoadjuvant chemotherapy endows CD9 with prognostic value that differs between tumor and stromal areas in patients with pancreatic cancer.

    Neoadjuvant chemotherapy endows CD9 with prognostic value that differs between tumor and stromal areas in patients with pancreatic cancer.
    Han X, Zhang WH, Gao HL, Li TJ, Xu HX, Li H, Li PC, Wang X, Yu XJ, Wang WQ, Liu L., Free PMC Article

    07/23/2022
    Tetraspanin CD9 Expression Predicts Sentinel Node Status in Patients with Cutaneous Melanoma.

    Tetraspanin CD9 Expression Predicts Sentinel Node Status in Patients with Cutaneous Melanoma.
    Lucarini G, Molinelli E, Licini C, Rizzetto G, Radi G, Goteri G, Mattioli-Belmonte M, Offidani A, Simonetti O., Free PMC Article

    05/21/2022
    How tetraspanin-mediated cell entry of SARS-CoV-2 can dysregulate the shedding of the ACE2 receptor by ADAM17.

    How tetraspanin-mediated cell entry of SARS-CoV-2 can dysregulate the shedding of the ACE2 receptor by ADAM17.
    Healy EF., Free PMC Article

    02/19/2022
    CD9 inhibition reveals a functional connection of extracellular vesicle secretion with mitophagy in melanoma cells.

    CD9 inhibition reveals a functional connection of extracellular vesicle secretion with mitophagy in melanoma cells.
    Suárez H, Andreu Z, Mazzeo C, Toribio V, Pérez-Rivera AE, López-Martín S, García-Silva S, Hurtado B, Morato E, Peláez L, Arribas EA, Tolentino-Cortez T, Barreda-Gómez G, Marina AI, Peinado H, Yáñez-Mó M., Free PMC Article

    01/22/2022
    CD9 and ITGA3 are regulated during HIV-1 infection in macrophages to support viral replication.

    CD9 and ITGA3 are regulated during HIV-1 infection in macrophages to support viral replication.
    Kruize Z, Cobos Jiménez V, Martinez FO, Di Vincenzo R, van Dort KA, van Nuenen AC, Booiman T, Kootstra NA.

    01/8/2022
    gammaENaC/CD9 in urinary extracellular vesicles as a potential biomarker of MR activity.

    γENaC/CD9 in urinary extracellular vesicles as a potential biomarker of MR activity.
    Hayakawa T, Fukuhara A, Saiki A, Otsuki M, Shimomura I.

    12/25/2021
    Interaction between CD9 and PI3Kp85 activates the PI3K/AKT signaling pathway in Blineage acute lymphoblastic leukemia.

    Interaction between CD9 and PI3K‑p85 activates the PI3K/AKT signaling pathway in B‑lineage acute lymphoblastic leukemia.
    Shi YF, Huang ZY, Huang YS, Dong RJ, Xing CY, Yu K, Leung KT, Feng JH.

    12/4/2021
    CD9 expression in vascular aging and atherosclerosis.

    CD9 expression in vascular aging and atherosclerosis.
    Kim JR, Choi JH.

    11/6/2021
    CD9 induces cellular senescence and aggravates atherosclerotic plaque formation.

    CD9 induces cellular senescence and aggravates atherosclerotic plaque formation.
    Cho JH, Kim EC, Son Y, Lee DW, Park YS, Choi JH, Cho KH, Kwon KS, Kim JR., Free PMC Article

    09/25/2021
    CD9 Upregulation-Decreased CCL21 Secretion in Mesenchymal Stem Cells Reduces Cancer Cell Migration.

    CD9 Upregulation-Decreased CCL21 Secretion in Mesenchymal Stem Cells Reduces Cancer Cell Migration.
    Hsieh CC, Hsu SC, Yao M, Huang DM., Free PMC Article

    09/11/2021
    Specificities of exosome versus small ectosome secretion revealed by live intracellular tracking of CD63 and CD9.

    Specificities of exosome versus small ectosome secretion revealed by live intracellular tracking of CD63 and CD9.
    Mathieu M, Névo N, Jouve M, Valenzuela JI, Maurin M, Verweij FJ, Palmulli R, Lankar D, Dingli F, Loew D, Rubinstein E, Boncompain G, Perez F, Théry C., Free PMC Article

    08/7/2021
    Implications for tetraspanin-enriched microdomain assembly based on structures of CD9 with EWI-F.

    Implications for tetraspanin-enriched microdomain assembly based on structures of CD9 with EWI-F.
    Oosterheert W, Xenaki KT, Neviani V, Pos W, Doulkeridou S, Manshande J, Pearce NM, Kroon-Batenburg LM, Lutz M, van Bergen En Henegouwen PM, Gros P., Free PMC Article

    07/17/2021
    CD9, a potential leukemia stem cell marker, regulates drug resistance and leukemia development in acute myeloid leukemia.

    CD9, a potential leukemia stem cell marker, regulates drug resistance and leukemia development in acute myeloid leukemia.
    Liu Y, Wang G, Zhang J, Chen X, Xu H, Heng G, Chen J, Zhao Y, Li J, Ni Y, Zhang Y, Shan J, Qian C., Free PMC Article

    07/17/2021
    Genetic Predisposition to Colon and Rectal Adenocarcinoma Is Mediated by a Super-enhancer Polymorphism Coactivating CD9 and PLEKHG6.

    Genetic Predisposition to Colon and Rectal Adenocarcinoma Is Mediated by a Super-enhancer Polymorphism Coactivating CD9 and PLEKHG6.
    Ke J, Tian J, Mei S, Ying P, Yang N, Wang X, Zou D, Peng X, Yang Y, Zhu Y, Gong Y, Wang Z, Gong J, Zhong R, Chang J, Miao X.

    07/10/2021
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