| Secreted aminoacyl-tRNA synthetase-interacting multifunctional protein-1 (AIMP1) is a promising predictor for the severity of acute AQP4-IgG positive neuromyelitis optica spectrum disorder. | Secreted aminoacyl-tRNA synthetase-interacting multifunctional protein-1 (AIMP1) is a promising predictor for the severity of acute AQP4-IgG positive neuromyelitis optica spectrum disorder.
Yuan C, Liu X, Cai S, Zhang L, Guo R, Jia Z, Sun Y, Li B. | 03/15/2023 |
| Endothelin-1 gene polymorphism (G8002A) and endothelial monocyte-activating polypeptide II: Role in vascular dysfunction in pediatric patients with beta-thalassemia major. | Endothelin-1 gene polymorphism (G8002A) and endothelial monocyte-activating polypeptide II: Role in vascular dysfunction in pediatric patients with β-thalassemia major.
Tantawy AAG, Tadros MAR, Adly AAM, Ismail EAR, Ibrahim FA, Salah Eldin NM, Hussein MM, Alfeky MA, Ibrahim SM, Hashem MA, Ebeid FSE. | 12/3/2022 |
| AIMP1 promotes multiple myeloma malignancy through interacting with ANP32A to mediate histone H3 acetylation. | AIMP1 promotes multiple myeloma malignancy through interacting with ANP32A to mediate histone H3 acetylation.
Wei R, Zhu Y, Zhang Y, Zhao W, Yu X, Wang L, Gu C, Gu X, Yang Y., Free PMC Article | 11/19/2022 |
| EMAP II Expression Is Increased on Peripheral Blood Cells from Non-Hodgkin Lymphoma. | EMAP II Expression Is Increased on Peripheral Blood Cells from Non-Hodgkin Lymphoma.
Saber MM., Free PMC Article | 10/1/2022 |
| Discovery of two distinct aminoacyl-tRNA synthetase complexes anchored to the Plasmodium surface tRNA import protein. | Discovery of two distinct aminoacyl-tRNA synthetase complexes anchored to the Plasmodium surface tRNA import protein.
Jaramillo Ponce JR, Kapps D, Paulus C, Chicher J, Frugier M., Free PMC Article | 07/2/2022 |
| Clinical powers of Aminoacyl tRNA Synthetase Complex Interacting Multifunctional Protein 1 (AIMP1) for head-neck squamous cell carcinoma. | Clinical powers of Aminoacyl tRNA Synthetase Complex Interacting Multifunctional Protein 1 (AIMP1) for head-neck squamous cell carcinoma.
Li Y, Liu H. | 05/28/2022 |
| the identification of FSCN1-binding partners enhances understanding of the mechanism of FSCN1-mediated malignant phenotypes, and these findings indicate that FSCN1 binds to AIMP1 and LTA4H might promote the progression of laryngeal squamous cell carcinoma . | Mass Spectrometric Analysis Identifies AIMP1 and LTA4H as FSCN1-Binding Proteins in Laryngeal Squamous Cell Carcinoma.
Gao W, An C, Xue X, Zheng X, Niu M, Zhang Y, Liu H, Zhang C, Lu Y, Cui J, Zhao Q, Wen S, Thorne RF, Zhang X, Wu Y, Wang B. | 06/27/2020 |
| This novel homozygous mutation of the AIMP1 gene is characterized by preserved development of the periventricular and deep white matter structures as demonstrated by MRI and MR spectroscopy correlation. | Novel Homozygous Mutation of the AIMP1 Gene: A Milder Neuroimaging Phenotype With Preservation of the Deep White Matter.
BoAli A, Tlili-Graiess K, AlHashem A, AlShahwan S, Zuccoli G, Tabarki B. | 03/28/2020 |
| The results from our study suggest that serum AIMP1 can be used to estimate the cross-sectional severe antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) population based on the Birmingham vasculitis activity score. | Serum Aminoacyl-tRNA Synthetase-Interacting Multifunctional Protein-1 Can Predict Severe Antineutrophil Cytoplasmic Antibody-Associated Vasculitis: A Pilot Monocentric Study.
Ahn SS, Kim JO, Yoon T, Song JJ, Park YB, Lee SW, Park SG., Free PMC Article | 12/14/2019 |
| The increase of EMAP-II serum level reflects an endothelial dysfunction in type 1 diabetes, alteration of carbohydrate and lipid metabolism could influence of this pathway. | SERUM LEVELS OF ENDOTHELIAL MONOCYTE ACTIVATING PEPTIDE II IN TYPE 1 DIABETES.
Mogylnytska LA, Mogylnytska OE. | 03/31/2018 |
| This study showed the potential of the anti-AIMP1 antibody as a therapeutic option for AD treatment. Also, the finding of an association of blood AIMP1 levels with the MMSE score. | Suppression of AIMP1 protects cognition in Alzheimer's disease model mice 3xTg-AD.
Jang S, Lee JH, Sohn BK, Kim E, Park SG, Yoon KJ, Park M, Kim EW, Jeong J, Lee JY, Kim CH, Namkoong K. | 01/13/2018 |
| systemic mRNA expression of AIMP1 strongly differentiated children who failed to achieve asthma control with triamcinolone administration | Systemic Corticosteroid Responses in Children with Severe Asthma: Phenotypic and Endotypic Features.
Fitzpatrick AM, Stephenson ST, Brown MR, Nguyen K, Douglas S, Brown LAS., Free PMC Article | 11/11/2017 |
| p43 induces both the mRNA and protein expression of IP-10. | p43 induces IP-10 expression through the JAK-STAT signaling pathway in HMEC-1 cells.
Wang W, Tan J, Xing Y, Kan N, Ling J, Dong G, Liu G, Chen H. | 03/11/2017 |
| Data indicate that AIMP1 downregulation using siRNA is a novel tool to restore TGF-beta signaling and thereby increases the chondrogenic potential of dedifferentiated/degenerated chondrocytes. | AIMP1 downregulation restores chondrogenic characteristics of dedifferentiated/degenerated chondrocytes by enhancing TGF-β signal.
Ahn J, Kumar H, Cha BH, Park S, Arai Y, Han I, Park SG, Lee SH., Free PMC Article | 12/17/2016 |
| two homozygous missense variants, p.(Gly299Arg) and p.(Val176Gly), in the gene AIMP1 that co-segregated with the phenotype, are reported. | Missense variants in AIMP1 gene are implicated in autosomal recessive intellectual disability without neurodegeneration.
Iqbal Z, Püttmann L, Musante L, Razzaq A, Zahoor MY, Hu H, Wienker TF, Garshasbi M, Fattahi Z, Gilissen C, Vissers LE, de Brouwer AP, Veltman JA, Pfundt R, Najmabadi H, Ropers HH, Riazuddin S, Kahrizi K, van Bokhoven H., Free PMC Article | 11/5/2016 |
| findings suggest EMAP II is elevated in type 1 diabetic patients, particularly those with micro-vascular complications; EMAP II levels are related to inflammation, glycemic control, albuminuria level of patients and the risk of micro-vascular complications | Endothelial monocyte activating polypeptide II in children and adolescents with type 1 diabetes mellitus: Relation to micro-vascular complications.
Adly AAM, Ismail EA, Tawfik LM, Ebeid FSE, Hassan AAS. | 08/27/2016 |
| AIMp1 promotes the proliferation and migration of fibroblasts/endothelial cells and importantly, pro-inflammatory gene expression in monocytes/macrophages and dendritic cells. | Stepping Out of the Cytosol: AIMp1/p43 Potentiates the Link Between Innate and Adaptive Immunity.
Liang D, Halpert MM, Konduri V, Decker WK. | 07/2/2016 |
| Increased serum level of EMAP-II may be one of the pathways of endothelial dysfunction in type 1 diabetes. | [SERUM LEVEL OF ENDOTHELIAL MONOCYTE ACTIVATING POLYPEPTIDE-II IN CHILDHOOD-ONSET TYPE 1 DIABETIC PATIENTS AND OBESE ADOLESCENTS].
Mogylnytska LA. | 05/7/2016 |
| AIMP1 appears to function as a novel inhibitor of PPARgamma that regulates adipocyte differentiation by preventing the transcriptional activation of PPARgamma. | AIMP1 negatively regulates adipogenesis by inhibiting PPARγ.
Kim JH, Lee JH, Park MC, Yoon I, Kim K, Lee M, Choi HS, Han JM, Kim S. | 11/14/2015 |
| Data indicate that HCV E2 glycoprotein interacts with cellular AIMP1/p43 protein and promotes cell surface expression of membrane glycoproteins gp96 and transforming growth factor beta TGF-beta signaling. | Degradation of AIMP1/p43 induced by hepatitis C virus E2 leads to upregulation of TGF-β signaling and increase in surface expression of gp96.
Kim MS, Kim S, Myung H., Free PMC Article | 10/24/2015 |
| Data indicate that the N terminus of Pro-EMAP II binds to its C terminus, arginyl-tRNA synthetase, and the neurofilament light subunit. | The N terminus of pro-endothelial monocyte-activating polypeptide II (EMAP II) regulates its binding with the C terminus, arginyl-tRNA synthetase, and neurofilament light protein.
Xu H, Malinin NL, Awasthi N, Schwarz RE, Schwarz MA., Free PMC Article | 06/27/2015 |
| EMAP2 is a multifunctional polypeptide with proinflammatory and antiangiogenic activity. (Review) | [Endothelial monocyte-activating polypeptide-II: properties, functions, and pathogenetic significance].
Mogylnytska LA. | 06/20/2015 |
| Kisspeptin effect on endothelial monocyte activating polypeptide II (EMAP-II)-associated lymphocyte cell death and metastases in colorectal cancer patients | Kisspeptin effect on endothelial monocyte activating polypeptide II (EMAP-II)-associated lymphocyte cell death and metastases in colorectal cancer patients.
Stathaki M, Armakolas A, Dimakakos A, Kaklamanis L, Vlachos I, Konstantoulakis MM, Zografos G, Koutsilieris M., Free PMC Article | 05/16/2015 |
| interactions between the N-terminal domains of ArgRS and AIMP1 are important for the catalytic and noncatalytic activities of ArgRS and for the assembly of the higher-order MSC protein complex with ArgRS-GlnRS-AIMP1 | Structure of the ArgRS-GlnRS-AIMP1 complex and its implications for mammalian translation.
Fu Y, Kim Y, Jin KS, Kim HS, Kim JH, Wang D, Park M, Jo CH, Kwon NH, Kim D, Kim MH, Jeon YH, Hwang KY, Kim S, Cho Y., Free PMC Article | 04/25/2015 |
| vascular contribution to lung development and the implications that vascular mediators such as EMAP II have in distal lung formation during the vulnerable stage of alveolar genesis. | Vascular mediators in chronic lung disease of infancy: role of endothelial monocyte activating polypeptide II (EMAP II).
Lal CV, Schwarz MA., Free PMC Article | 11/22/2014 |