| High expression of TBRG4 in relation to unfavorable outcome and cell ferroptosis in hepatocellular carcinoma. | High expression of TBRG4 in relation to unfavorable outcome and cell ferroptosis in hepatocellular carcinoma.
Tao S, Cui D, Cheng H, Liu X, Jiang Z, Chen H, Gao Y., Free PMC Article | 02/17/2024 |
| Mitochondrial protein, TBRG4, modulates KSHV and EBV reactivation from latency. | Mitochondrial protein, TBRG4, modulates KSHV and EBV reactivation from latency.
Zhang H, Wong JP, Ni G, Cano P, Dittmer DP, Damania B., Free PMC Article | 12/3/2022 |
| The FASTK family proteins fine-tune mitochondrial RNA processing. | The FASTK family proteins fine-tune mitochondrial RNA processing.
Ohkubo A, Van Haute L, Rudler DL, Stentenbach M, Steiner FA, Rackham O, Minczuk M, Filipovska A, Martinou JC., Free PMC Article | 01/8/2022 |
| Expression quantitative trait loci of genes predicting outcome are associated with survival of multiple myeloma patients. | Expression quantitative trait loci of genes predicting outcome are associated with survival of multiple myeloma patients.
Macauda A, Piredda C, Clay-Gilmour AI, Sainz J, Buda G, Markiewicz M, Barington T, Ziv E, Hildebrandt MAT, Belachew AA, Varkonyi J, Prejzner W, Druzd-Sitek A, Spinelli J, Andersen NF, Hofmann JN, Dudziński M, Martinez-Lopez J, Iskierka-Jazdzewska E, Milne RL, Mazur G, Giles GG, Ebbesen LH, Rymko M, Jamroziak K, Subocz E, Reis RM, Garcia-Sanz R, Suska A, Haastrup EK, Zawirska D, Grzasko N, Vangsted AJ, Dumontet C, Kruszewski M, Dutka M, Camp NJ, Waller RG, Tomczak W, Pelosini M, Raźny M, Marques H, Abildgaard N, Wątek M, Jurczyszyn A, Brown EE, Berndt S, Butrym A, Vachon CM, Norman AD, Slager SL, Gemignani F, Canzian F, Campa D., Free PMC Article | 09/11/2021 |
| TBRG4 silencing promotes progression of squamous cell carcinoma via regulation of CAV-1 expression and ROS formation. | TBRG4 silencing promotes progression of squamous cell carcinoma via regulation of CAV-1 expression and ROS formation.
Wang J, Luo Q, Liu M, Zhang C, Jia Y, Tong R, Yang L, Fu X. | 01/2/2021 |
| Despite the fact that proteins of the FASTK family FASTKD1-5 share the same domains, they exhibit various-sometimes opposing-functions in almost all steps of mitochondrial RNA metabolism. | The FASTK family of proteins: emerging regulators of mitochondrial RNA biology.
Jourdain AA, Popow J, de la Fuente MA, Martinou JC, Anderson P, Simarro M., Free PMC Article | 12/2/2017 |
| Disruption of FASTKD4 reduces the level of ND3 and of other mature mRNAs including ND5 and CYB, and causes accumulation of ND5-CYB precursor RNA. Disrupting FASTKD1 and FASTKD4 decreases ND3 mRNA like depleting FASTKD4 alone, indicating that FASTKD4 loss is epistatic. RAP domain of FASTKD4 has a nuclease fold with a conserved aspartate at the putative active site, mutation of which abolishes its function. | FASTKD1 and FASTKD4 have opposite effects on expression of specific mitochondrial RNAs, depending upon their endonuclease-like RAP domain.
Boehm E, Zaganelli S, Maundrell K, Jourdain AA, Thore S, Martinou JC., Free PMC Article | 10/7/2017 |
| SLERT is 694 nucleotides & contains SNORA5A & SNORA5C at its ends; it is produced from the human TBRG4 locus via skipping of exons 4 and 5 that leads to both SNORA5A & SNORA5C embedded within one intron, thereby producing SLERT from this alternatively spliced intron; results reveal an important control of ribosome biogenesis by SLERT lncRNA & its regulatory role in DDX21 ring-shaped arrangements acting on Pol I complexes. | SLERT Regulates DDX21 Rings Associated with Pol I Transcription.
Xing YH, Yao RW, Zhang Y, Guo CJ, Jiang S, Xu G, Dong R, Yang L, Chen LL. | 07/8/2017 |
| Observational study of gene-disease association. (HuGE Navigator) | Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.
Hendrickson SL, Lautenberger JA, Chinn LW, Malasky M, Sezgin E, Kingsley LA, Goedert JJ, Kirk GD, Gomperts ED, Buchbinder SP, Troyer JL, O'Brien SJ., Free PMC Article | 12/5/2010 |
| Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR., Free PMC Article | 06/30/2010 |
| 13 human CPR (cell cycle progression restoration) genes and 11 yeast OPY (overproduction-induced pheromone-resistant yeast) genes that specifically block the G1 arrest by mating pheromone. | Human CPR (cell cycle progression restoration) genes impart a Far- phenotype on yeast cells.
Edwards MC, Liegeois N, Horecka J, DePinho RA, Sprague GF Jr, Tyers M, Elledge SJ., Free PMC Article | 11/10/2005 |