| Decreased Serum Levels of Soluble Oncostatin M Receptor (sOSMR) and Glycoprotein 130 (sgp130) in Patients with Coronary Artery Disease. | Decreased Serum Levels of Soluble Oncostatin M Receptor (sOSMR) and Glycoprotein 130 (sgp130) in Patients with Coronary Artery Disease.
Carvalho VMF, Oliveira PSS, Albuquerque APB, Rêgo MJBM, Rosa MMD, Oliveira DC, Pereira MC, Pitta MGDR., Free PMC Article | 05/1/2023 |
| Oncostatin M receptor is overexpressed in oral squamous cell carcinoma and connected to poor prognosis. | Oncostatin M receptor is overexpressed in oral squamous cell carcinoma and connected to poor prognosis.
Geng Q, Wang J, Zhang W, Zhou W, Tang G, Gu M. | 02/24/2023 |
| Association of oncostatin M receptor polymorphisms with clinical recurrence of ovarian cancer in the Chinese Han population. | Association of oncostatin M receptor polymorphisms with clinical recurrence of ovarian cancer in the Chinese Han population.
Li Q, Wang Y, Li Z, Su M, Song Y, Hu Q, Zhou B, Zhang L. | 05/7/2022 |
| The Role of Oncostatin M and Its Receptor Complexes in Cardiomyocyte Protection, Regeneration, and Failure. | The Role of Oncostatin M and Its Receptor Complexes in Cardiomyocyte Protection, Regeneration, and Failure.
Kubin T, Gajawada P, Bramlage P, Hein S, Berge B, Cetinkaya A, Burger H, Schönburg M, Schaper W, Choi YH, Richter M., Free PMC Article | 04/16/2022 |
| OSMRbeta mutants enhance basal keratinocyte differentiation via inactivation of the STAT5/KLF7 axis in PLCA patients. | OSMRβ mutants enhance basal keratinocyte differentiation via inactivation of the STAT5/KLF7 axis in PLCA patients.
Liu J, Chen J, Zhong Y, Yu X, Lu P, Feng J, Zhang X, Ma S, Yang C, Yang B, Rong Z., Free PMC Article | 01/29/2022 |
| Heterocellular OSM-OSMR signalling reprograms fibroblasts to promote pancreatic cancer growth and metastasis. | Heterocellular OSM-OSMR signalling reprograms fibroblasts to promote pancreatic cancer growth and metastasis.
Lee BY, Hogg EKJ, Below CR, Kononov A, Blanco-Gomez A, Heider F, Xu J, Hutton C, Zhang X, Scheidt T, Beattie K, Lamarca A, McNamara M, Valle JW, Jørgensen C., Free PMC Article | 01/15/2022 |
| Oncostatin M Receptor-Targeted Antibodies Suppress STAT3 Signaling and Inhibit Ovarian Cancer Growth. | Oncostatin M Receptor-Targeted Antibodies Suppress STAT3 Signaling and Inhibit Ovarian Cancer Growth.
Geethadevi A, Nair A, Parashar D, Ku Z, Xiong W, Deng H, Li Y, George J, McAllister DM, Sun Y, Kadamberi IP, Gupta P, Dwinell MB, Bradley WH, Rader JS, Rui H, Schwabe RF, Zhang N, Pradeep S, An Z, Chaluvally-Raghavan P., Free PMC Article | 01/8/2022 |
| Oncostatin-M Does Not Predict Treatment Response in Inflammatory Bowel Disease in a Pediatric Cohort. | Oncostatin-M Does Not Predict Treatment Response in Inflammatory Bowel Disease in a Pediatric Cohort.
Ezirike Ladipo J, He Z, Chikwava K, Robbins K, Beri J, Molle-Rios Z. | 10/30/2021 |
| Whole-exome analysis of metaplastic breast carcinomas with extensive osseous differentiation. | Whole-exome analysis of metaplastic breast carcinomas with extensive osseous differentiation.
Beca F, Sebastiao APM, Pareja F, Dessources K, Lozada JR, Geyer F, Selenica P, Zeizafoun N, Wen HY, Norton L, Brogi E, Weigelt B, Reis-Filho JS., Free PMC Article | 08/21/2021 |
| The OSMR Gene Is Involved in Hirschsprung Associated Enterocolitis Susceptibility through an Altered Downstream Signaling. | The OSMR Gene Is Involved in Hirschsprung Associated Enterocolitis Susceptibility through an Altered Downstream Signaling.
Bachetti T, Rosamilia F, Bartolucci M, Santamaria G, Mosconi M, Sartori S, De Filippo MR, Di Duca M, Obino V, Avanzini S, Mavilio D, Candiani S, Petretto A, Pini Prato A, Ceccherini I, Lantieri F., Free PMC Article | 05/22/2021 |
| Feline Interleukin-31 Shares Overlapping Epitopes with the Oncostatin M Receptor and IL-31RA. | Feline Interleukin-31 Shares Overlapping Epitopes with the Oncostatin M Receptor and IL-31RA.
Medina-Cucurella AV, Bammert GF, Dunkle W, Javens C, Zhu Y, Mutchler VT, Teel JT, Stein CA, Dunham SA, Whitehead TA., Free PMC Article | 02/27/2021 |
| Annexin A2-STAT3-Oncostatin M receptor axis drives phenotypic and mesenchymal changes in glioblastoma. | Annexin A2-STAT3-Oncostatin M receptor axis drives phenotypic and mesenchymal changes in glioblastoma.
Matsumoto Y, Ichikawa T, Kurozumi K, Otani Y, Fujimura A, Fujii K, Tomita Y, Hattori Y, Uneda A, Tsuboi N, Kaneda K, Makino K, Date I., Free PMC Article | 01/16/2021 |
| Oncostatin M, A Profibrogenic Mediator Overexpressed in Non-Alcoholic Fatty Liver Disease, Stimulates Migration of Hepatic Myofibroblasts. | Oncostatin M, A Profibrogenic Mediator Overexpressed in Non-Alcoholic Fatty Liver Disease, Stimulates Migration of Hepatic Myofibroblasts.
Foglia B, Sutti S, Pedicini D, Cannito S, Bocca C, Maggiora M, Bevacqua MR, Rosso C, Bugianesi E, Albano E, Novo E, Parola M., Free PMC Article | 08/29/2020 |
| Overexpression of LINC00520 contributes to the aggravation of Acute kidney injury by targeting miR-27b-3p/ OSMR. | LINC00520 targeting miR-27b-3p regulates OSMR expression level to promote acute kidney injury development through the PI3K/AKT signaling pathway.
Tian X, Ji Y, Liang Y, Zhang J, Guan L, Wang C. | 05/30/2020 |
| High OSMR expression is associated with metastasis in gastric cancer. | Oncostatin M receptor, positively regulated by SP1, promotes gastric cancer growth and metastasis upon treatment with Oncostatin M.
Yu Z, Li Z, Wang C, Pan T, Chang X, Wang X, Zhou Q, Wu X, Li J, Zhang J, Liu B, Zhu Z, Su L. | 02/15/2020 |
| The present data indicate OSMR mutations as not only the main cause of fPLCA, but also the potential source of the pathogenesis of sPLCA, although the exact molecular mechanism remains unknown. | Clinical and genetic features of Chinese patients with lichen and macular primary localized cutaneous amyloidosis.
Lu P, Wu FF, Rong ZL, Fang C, Deng CC, Bin LH, Yang B. | 01/11/2020 |
| OSMR genotype frequencies were found to be associated with higher recurrence in bladder cancer, and it may serve as a biomarker candidate gene to predict prognosis of this disease. | The role of oncostatin M receptor gene polymorphisms in bladder cancer.
Deng S, He SY, Zhao P, Zhang P., Free PMC Article | 03/23/2019 |
| substitution of the AB loop and D-helix in LIF with their OSM counterparts was sufficient for OSMR activation | The AB loop and D-helix in binding site III of human Oncostatin M (OSM) are required for OSM receptor activation.
Adrian-Segarra JM, Schindler N, Gajawada P, Lörchner H, Braun T, Pöling J., Free PMC Article | 02/2/2019 |
| The current study suggested that the OSMR gene is highly expressed in human chronic autoimmune urticaria (CAU) skin tissues, and cause the up-regulation of the JAK/STAT3 signaling pathway-related genes. OSMR gene silencing in mice inhibits the activation of the JAK/STAT3 signaling pathway, thereby suppressing the development of CAU. | OSMR gene effect on the pathogenesis of chronic autoimmune Urticaria via the JAK/STAT3 pathway.
Luo XY, Liu Q, Yang H, Tan Q, Gan LQ, Ren FL, Wang H., Free PMC Article | 01/19/2019 |
| Polymorphisms of the OSMR rs2292016 locus are related to the development and outcome of DCM. | [Association of OSMR gene polymorphisms with dilated cardiomyopathy in a Han Chinese population].
Dai X, Peng Y, Zhou B, Li C, Song H, Dou Q, Xie X, Rao L. | 08/25/2018 |
| Missense mutatios were found in exon 10 of the oncostatin-M specific receptor beta subunit (OSMR) gene in all of the six patients from family 1, and in exon 14 of the OSMR gene in all of the four patients from family 2. | [Identification of pathogenic mutations in two Chinese families affected with primary localized cutaneous amyloidosis].
Mao B, Yao X, Wang Z, Zhao X. | 06/9/2018 |
| The PLAC1 expression has been demonstrated for the first time in cervical cancers. This preliminary study has further revealed a complex relationship between PLAC1 expression, cervical cancer histologic type, p53, and HPV type that requires further investigation. | Placenta-Specific Protein 1 Expression in Human Papillomavirus 16/18-Positive Cervical Cancers Is Associated With Tumor Histology.
Devor EJ, Reyes HD, Gonzalez-Bosquet J, Warrier A, Kenzie SA, Ibik NV, Miller MD, Schickling BM, Goodheart MJ, Thiel KW, Leslie KK., Free PMC Article | 01/13/2018 |
| OSMR-beta deficiency in macrophages improved high-fat diet-induced atherogenesis and plaque vulnerability | Oncostatin M receptor β deficiency attenuates atherogenesis by inhibiting JAK2/STAT3 signaling in macrophages.
Zhang X, Li J, Qin JJ, Cheng WL, Zhu X, Gong FH, She Z, Huang Z, Xia H, Li H., Free PMC Article | 12/23/2017 |
| OSM and OSMR are highly expressed in inflammatory bowel disease intestinal mucosa compared to control mucosa. Intestinal stromal cells express abundant OSMR. | Oncostatin M drives intestinal inflammation and predicts response to tumor necrosis factor-neutralizing therapy in patients with inflammatory bowel disease.
West NR, Hegazy AN, Owens BMJ, Bullers SJ, Linggi B, Buonocore S, Coccia M, Görtz D, This S, Stockenhuber K, Pott J, Friedrich M, Ryzhakov G, Baribaud F, Brodmerkel C, Cieluch C, Rahman N, Müller-Newen G, Owens RJ, Kühl AA, Maloy KJ, Plevy SE, Oxford IBD Cohort Investigators, Keshav S, Travis SPL, Powrie F., Free PMC Article | 08/19/2017 |
| OSM:OSMR interactions are able to induce EMT, increased cancer stem cell-like properties and enhanced lung colonisation in SCC cells | Overexpression of the oncostatin-M receptor in cervical squamous cell carcinoma is associated with epithelial-mesenchymal transition and poor overall survival.
Kucia-Tran JA, Tulkki V, Smith S, Scarpini CG, Hughes K, Araujo AM, Yan KY, Botthof J, Pérez-Gómez E, Quintanilla M, Cuschieri K, Caffarel MM, Coleman N., Free PMC Article | 05/20/2017 |